Effects of a novel perfluorocarbon emulsion on neutrophil chemiluminescence in human whole blood in vitro

Artificial Cells, Blood Substitutes, and Immobilization Biotechnology

Volumn 25, Issue 3, 1997, Pages 255-260

  Edwards, C M ^a   Lowe, K C ^a   Rohlke W ^b   Geister, U ^b   Reuter, P ^b   Meinert, H ^b  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CELLS; CHEMILUMINESCENCE; COMPOSITION EFFECTS; EMULSIONS;

INCUBATION; LECITHIN; NEUTROPHILS; PERFLUOROCARBON (PFC) EMULSION;

FLUOROCARBONS;

FLUOROCARBON; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLCHOLINE; POLOXAMER;

ARTICLE; CELL STIMULATION; CHEMOLUMINESCENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMULSION; HUMAN; HUMAN CELL; NEUTROPHIL;

EID: 0031149718     PISSN: 10731199     EISSN: None     Source Type: Journal    
DOI: 10.3109/10731199709118915     Document Type: Article

References (11)

1. Biro, G.P. Perfluorocarbon-based red blood cell substitutes. Trans. Med. Rev 7, 84-95 (1993).
2. Lowe, K.C Perfluorochemicals in vascular medicine. Vasc. Med. Rev. 5, 15-32 (1994)
3. Zuck, T.F. and Riess, J.G. Current status of injectable oxygen carriers. Crit. Rev. Clin. Lab. Sci. 31, 295-324 (1994).
4. Forman, M.B., Ingram, D.A. and Murray, J.J. Attenuation of myocardial reperfusion injury by perfluorochemical emulsions. Clin. Hemorheol. 12, 121-140 (1992a).
5. Forman, M.B., Pitarys, C.J., Vildibill, H.D., Lambert, T.L., Ingram, D.A., Virmani, R. and Murray, J.J. Pharmacologic perturbation of neutrophils by Fluosol results in a sustained reduction in infarct size in the canine model of reperfusion. J. Am. Coll. Cardiol. 19, 205-216 (1992b).
6. Schaer, G.L., Hursey, T.L., Abrahams, S.L., Buddemeier, K., Ennis, B., Rodriguez, R., Hubbell, J.P., Moy, J. and Parrillo, J E. Reduction in reperfusion-induced myocardial injury in dogs by RheothRx® Injection (Poloxamer 188 N.F.), a hemorheological agent that alters neutrophil function. Circulation 90, 2964-2975 (1994).
7. Neilson, C.P., Crowley, J.J., Vestal, R.E. and Connolly, M.J. Impaired beta-adrenoceptor function, increased leukocyte respiratory burst, and bronchial hyperresponsiveness. J. Allergy Clin. Immunol. 90, 825-832 (1992).
8. Snedecor, G.W. and Cochran, W.G. Statistical Methods, 8th Edn., Ames, Iowa State College Press, 1989.
9. Castagna, M., Takai, Y., Kaibuchi, K., Sano, K., Kikkawa, U. and Nishizuka, Y. Direct activation of calcium activated, phospholipid-dependent protein kinases by tumour-promoting phorbol esters. J. Biol. Chem. 257, 7847-7851 (1982).
10. Smith, T.M., Steinhorn, D.M., Thusu, K., Fuhrman B.P. and Dandona, P. A liquid perfluorochemical decreases the in vitro production of reactive oxygen species by alveolar macrophages. Crit. Care Med. 23, 1533-1539 (1995).
11. Lowe, K.C. Emulsified perfluorochemicals for oxygen transport to tissues: effects on lymphoid system and immunological competence. In Oxygen Transport to Tissue, Vol. 10, Mochizuki, M , Honig, C.R., Koyama, T., Goldstick, T.K., Bruley, D.F. (Eds.), pp. 655-663. New York, Plenum, 1988.