Molecular characterization of human neogenin, a DCC-related protein, and the mapping of its gene (NEO1) to chromosomal position 15q22.3-q23

Genomics

Volumn 41, Issue 3, 1997, Pages 414-421

  Vielmetter, Jost ^a,c   Chen, Xiao Ning ^b   Miskevich, Frank ^a   Lane, Robert P ^a   Yamakawa, Kazuhiro ^b   Korenberg, Julie R ^b   Dreyer, William J ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

^c Clinical Micro Sensors   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; NEOGENIN; NERVE CELL ADHESION MOLECULE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHICK EMBRYO; CHROMOSOME 15Q; EMBRYO; EMBRYO DEVELOPMENT; FETUS; GENE MAPPING; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOLECULAR GENETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

EID: 0031149451     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1997.4688     Document Type: Article

References (26)

1. Carmi, R., Elbedour, K., and Stone, E. M. (1995a). Phenotypic differences among patients with Bardet-Biedl syndrome linked to 3 different chromosome loci. Am. J. Med. Genet. 59: 199-203.
2. Carmi, R., Rokhlina, T., Kwitekblack, A. E., Elbedour, K., Nishimura, D., Stone, E. M., and Sheffield, V. C. (1995b). Use of a DNA pooling strategy to identify a human obesity syndrome locus on chromosome 15. Hum. Mol. Genet. 4: 9-13.
3. Chin, J. E., Dickens, M., Tavare, J. M., and Roth, R. A. (1993). Overexpression of protein-kinase-C isoenzymes-alpha, beta-I, gamma and epsilon in cells overexpressing the insulin-receptor - Effects on receptor, phosphorylation and signaling. J. Biol. Chem. 268: 6338-6347.
4. Cho, K. R., and Fearon, E. R. (1995). DCC - Linking tumor suppressor genes and altered cell-surface interactions in cancer. Eur. J. Cancer 31: 1055-1060.
5. Christianson, D. W. (1991). Structural biology of zinc. Adv. Protein Chem. 42: 281-355.
6. Chuong, C. M., Jiang, T. X., Yin, E., and Widelitz, R. B. (1994). CDCC (Chicken homolog to a gene deleted in colorectal carcinoma) is an epithelial adhesion molecule expressed in the basal cells and involved in epithelial-mesenchymal interaction. Dev. Biol. 164: 383-397.
7. Cooper, H. M., Armes, P., Britto, J., Gad, J., and Wilks, A. F. (1995). Cloning of the mouse homolog of the deleted in colorectal-cancer gene (MDCC) and its expression in the developing mouse embryo. Oncogene 11: 2243-2254.
8. Fearon, E. R., Cho, K. R., Nigro, J. M., Kern, S. E., Simons, J. W., Ruppert, J. M., Hamilton, S. R., Preisinger, A. C., Thomas, G., Kinzler, K. W., and Vogelstein, B. (1990). Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 247: 49-56.
9. Hedrick, L., Cho, K. R., Fearon, E. R., Wu, T., Kinzler, K. W., and Vogelstein, B. (1994). The DCC gene product in cellular differentiation and colorectal tumorigenesis. Genes Dev. 8: 1174-1183.
10. Jouet, M., Rosenthal, A., Armstrong, G., MacFarlane, J., Stevenson, R., Paterson, J., Metzenberg, A., Ionasescu, V., Temple, K., and Kenwrick, S. (1994). X-linked spastic paraplegia (SPG1), MASA syndrome and X-linked hydrocephalus result from mutations in the L1 gene. Nature Genet. 7: 402-407.
11. Korenberg, J. R., and Chen, X.-N. (1995). Human cDNA mapping using a high resolution R-banding technique and fluorescence in situ hybridization. Cytogenet. Cell Genet. 69: 196-200.
12. Kozak, M. (1989). The scanning model for translation. J. Cell Biol. 108: 229-241.
13. Kyte, J., and Doolittle, R. F. (1982). A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157: 105-132.
14. Lawlor, K. G., and Narayanan, R. (1992). Persistent expression of the tumor suppressor gene DCC is essential for neuronal differentiation. Cell Growth Differ. 3: 609-616.
15. Ledouarin, N. M. (1993). Embryonic neural chimaeras in the study of brain development. Trends Neurosci. 16: 64-72.
16. Marshal, R. D. (1972). Glycoproteins. Annu. Rev. Biochem. 41: 673-707.
17. Mayer, B. J., and Eck, M. J. (1995). SH3 domains - Minding your Ps and Qs. Curr. Biol. 5: 364-367.
18. Needleman, S. B., and Wunsch, C. D. (1970). A general method applicable to the search for similarities in the amino acid sequence of two proteins. J. Mol. Biol. 48: 443-453.
19. Pierceall, W. E., Cho, K. R., Getzenberg, R. H., Reale, M. A., Hedrick, L., and Fearon, E. R. (1994a). NIH3T3 cells expressing the deleted in colorectal cancer tumor suppressor gene product stimulate neurite outgrowth in rat PC12 pheochromocytoma cells. J. Cell Biol. 124: 1017-1027.
20. Pierceall, W. E., Reale, M. A., Candia, A. F., Wright, C. V. E., Cho, K. R., and Fearon, E. R. (1994b). Expression of a homologue of the deleted in colorectal cancer (DCC) gene in the nervous system of developing Xenopus embryos. Dev. Biol. 166: 654-665.
21. Vaughn, D. E., and Bjorkman, P. J. (1996). The (Greek) key to structures of neural adhesion molecules. Neuron 16: 261-273.
22. Vielmetter, J., Kayyem, J. F., Roman, J. M., and Dreyer, W. J. (1994). Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation, is closely related to the human tumor suppressor molecule deleted in colorectal cancer. J. Cell Biol. 127: 2009-2020.
23. Vonheijne, G. (1990). The signal peptide. J. Membrane Biol. 115: 195-201.
24. Williams, A. F., and Barclay, A. N. (1988). The immunoglobulin superfamily - Domains for cell surface recognition. Annu. Rev. Immunol. 6: 381-405.
25. Woodgett, J. R., Gould, K. L., and Hunter, T. (1986). Substrate-specificity of protein kinase C: Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements. Eur. J. Biochem. 161: 177-184.
26. Yamakawa, K., Mitchell, S., Hubert, R., Chen, X-N., Colbern, S., Huo, Y-K., Gadomski, C., Kim, U-J., and Korenberg, J. R. (1995). Isolation and characterization of a candidate gene for progressive myoclonus epilepsy on 21q22.3. Hum. Mol. Genet. 4: 709-716.