Reduced dopamine levels in PC12 cells exposed to low frequency electromagnetic fields

Bioelectrochemistry and Bioenergetics

Volumn 42, Issue 2, 1997, Pages 235-239

  Opler, Mark ^a   Rukenstein, Adriana ^a   Coté, Lucien ^a   Goodman, Reba ^a  

^a NewYork Presbyterian Hospital   (United States)

Author keywords

(elf EM) fields; Catecholamine metabolism; Coherence; Dopac; Dopamine; Electrochemical detection (ED); Extremely low electromagnetic; High pressure liquid chromatography (HPLC); Magnetic noise (N) fields; PC12 neuronal pheochromocytoma cells

Indexed keywords

AMINES; ELECTROMAGNETIC FIELD EFFECTS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HORMONES; METABOLISM;

DOPAMINE; NEURONAL CELLS;

ANIMAL CELL CULTURE;

3,4 DIHYDROXYPHENYLACETIC ACID; CATECHOLAMINE DERIVATIVE; DOPAMINE;

CATECHOLAMINE METABOLISM; CONFERENCE PAPER; ELECTROMAGNETIC FIELD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; PHEOCHROMOCYTOMA CELL;

EID: 0031148674     PISSN: 03024598     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0302-4598(96)05115-X     Document Type: Conference Paper

References (20)

1. E.M. Goodman, B. Greenebaum and M.T. Marron, Effects of electromagnetic fields on molecules and cells, Int. Rev. Cytol., 158 (1995) 279-338.
2. L.A. Greene and A.S. Tischler, Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor, Proc. Natl. Acad. Sci. USA, 73 (1976) 2424-2428.
3. 3H-noradrenaline release potentiated in a clonal nerve cell line by low-intensity pulsed magnetic fields, Nature, 296 (1982) 253-256.
4. L.A. Greene and G. Rein, Release, storage and uptake of catecholamines by a clonal cell line of nerve growth factor (NGF) responsive pheochromocytoma cells, Brain Res., 129 (1977) 247-263.
5. L.A. Greene and G. Rein, Synthesis, storage and release of acetylcholine by a noradrenergic pheochromocytoma cell line, Nature, 268 (1977) 349-351
6. M.A. Dichter, A.S. Tischler and L.A. Greene, Nerve growth factor-induced increase in electrical excitability and acetylcholine sensitivity of a rat pheochromocytoma cell line, Nature, 268 (1977) 501-504.
7. H. Nakae, Morphological differentiation of rat pheochromocytoma cells (PC12 cells) by electric stimulation, Brain Res., 558 (1991) 348-352.
8. R.J. Cork, M.E. McGinnis, J. Tsai and K.R. Robinson, The growth of PC12 neuntes is biased towards the anode of an applied electrical field, J. Neurobiol., 225 (1994) 1509-1515.
9. C.F. Blackman, S.G. Benane, D.E. House and D.E. House, Evidence for direct effect of magnetic fields on neunte outgrowth, FASEB J., 7 (1993) 801-806.
10. S. Ohtsu, J. Miyakoshi, T. Tsukada, M. Hiraoka, M. Abe and H. Takebe, Enhancement of beta-galactosidase gene expression in rat pheochromocytoma cells by exposure to extremely low frequency magnetic fields, Biochem. Biophys. Res. Commun., 212 (1) (1995) 104-109.
11. T.A. Litovitz, J.M. Mullins and D. Krause, Effect of coherence time of the applied magnetic field on omithine decarboxylase activity, Biochem. Biophys. Res. Commun., 178 (1991) 862-865.
12. T.A. Litovitz, D. Krause, C.J. Montrose and J.M. Mullins, Temporally incoherent magnetic fields mitigate the response of biological systems to temporally coherent magnetic fields, Bioelectromagnetics, 15 (1994) 399-409.
13. H. Lin and R. Goodman, EM noise blocks the 60Hz magnetic field enhancement of c-myc in human leukemia cells, Bioelectrochem. Bioenerg., 36 (1995) 33-37.
14. J.M. Mullins, D. Krause and T.A. Litovitz, Simultaneous application of a spatially coherent noise field blocks the response of cell cultures to a 60 Hz electromagnetic field, in Blank M (ed.), Electricity and Magnetism in Biology and Medicine, San Francisco Press, San Francisco, CA, 1993.
15. C. Sommer, P. Gass and M. Kiessling, Selective c-jun expression in CAl neurons of the gerbil hippocampus during and after acquisition of an ischemia-tolerant state, Brain Pathol., 5 (1995) 1135-1144.
16. A. Bukh, H. Martinez-Valdez, S.J. Freedman, M.H. Freedman and A. Cohen, The expression of c-fos, c-jun and c-myc genes is regulated by heat shock in human lymphoid cells, Am. J. Immunol., 144 (1990) 4835-4840.
17. S. Lindquist and E.A. Craig, The heat shock proteins, Ann. Rev. Genet., 22 (1988) 631-677.
18. R.I. Morimoto, Heat Shock: The role of transient inducible responses in cell damage, transformation and differentiation, Cancer Cells, 3 (1991) 295-301.
19. J.C.L. Plumier and R.W. Currie, Heat shock-induced myocardial protection against ischemic injury: a role for Hsp70? Cell Stress and Chaperones, 1 (1996) 13-17.
20. W. van Eden and D.B. Young, Stress Proteins in Medicine, Marcel Dekker, New York, 1996.