Exogenous fatty acids modulate the functional and cytotoxic responses of cultured pulmonary artery endothelial cells to oxidant stress

Journal of Laboratory and Clinical Medicine

Volumn 129, Issue 5, 1997, Pages 548-556

  Karman, Robert J ^a   Gupta, Mahesh P ^a   Garcia, Joe G N ^a   Hart, C Michael ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b Div Pulmon and Critical Care Med   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031148296     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2143(97)90009-3     Document Type: Article

References (35)

1. Cross CE. Oxygen radicals and human disease. Ann Intern Med 1987;107:526-45.
2. Horton AA, Fairhurst S. Lipid peroxidation and mechanisms of toxicity. Crit Rev Toxicol 1987;18:27-79.
3. Hart CM, Tolson JK, Block ER. Fatty acid supplementation protects pulmonary artery endothelial cells from oxidant injury. Am J Respir Cell Mol Biol 1990;3:479-89.
4. Hart CM, Toison JK, Block ER. Supplemental fatty acids alter lipid peroxidation and oxidant injury in endothelial cells. Am J Physiol 1991;260:L481-8.
5. Hart CM, Tolson JK, Block ER. Quantitative fatty acid analyses in cultured porcine pulmonary artery endothelial cells: the combined effects of fatty acid supplementation and oxidant exposure. J Cell Physiol 1992;153:76-87.
6. Hart CM, Andreoli SP, Patterson CE, Garcia JGN. Oleic acid supplementation reduces oxidant-mediated dysfunction of cultured porcine pulmonary artery endothelial cells. J Cell Physiol 1993;156:24-34.
7. Spector A. Metabolism of free fatty acids. Prog Biochem Pharmacol 1971;6:130-76.
8. Folch J, Lees M, Sloane-Stanley GH. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957;226:497-509.
9. Morrison WR, Smith LM. Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron flouride-methanol. J Lipid Res 1964;5:600-8.
10. Patterson CE, Rhoades RA, Garcia JGN. Evans blue dye as a marker of albumin clearance in cultured endothelial monolayer and isolated lung. J Appl Physiol 1992;72:865-73.
11. Moldow CF, Jacob HS. Endothelial culture, neutrophil or enzymatic generation of free radicals: in vitro methods for the study of endothelial cell injury. Methods Enzymol 1984; 105:378-85.
12. Dito WR. Lactate dehydrogenase: a brief review. In: Griffith JC, editor. Clinical enzymology. New York: Masson Press, 1979:1-16.
13. Winer BJ, editor. Statistical principles in experimental design. New York: McGraw-Hill, 1962.
14. Kinsella JE, Broughton KS, Whelan JW. Dietary unsaturated fatty acids: interactions and possible needs in relation to eicosanoid synthesis. J Nutr Biochem 1990;1:123-41.
15. Hennig B, Shasby DM, Fulton AB, Spector AA. Exposure to free fatty acid increases the transfer of albumin across cultured endothelial monolayers. Arteriosclerosis 1984;4:489-97.
16. Balasubramanian KA, Nalini S, Cheeseman KH, Slater TF. Nonesterified fatty acids inhibit iron-dependent lipid peroxidation. Biochim Biophys Acta 1989;1003:232-7.
17. Ruch R J, Crist KA, Klaunig JE. Effects of culture duration on hydrogen peroxide-induced hepatocyte toxicity. Toxicol Appl Pharmacol 1989;100:451-64.
18. Freeman BA, Young SL, Crapo JD. Liposome-mediated augmentation of Superoxide dismutase in endothelial cells prevents oxygen injury. J Biol Chem 1983;258:12534-42.
19. Schatte CL, Mathias MM. Effect of dietary fat on pulmonary enzymes and toxicity during normobaric hyperoxia. Aviat Space Environ Med 1982;53:629-32.
20. Spitz DR, Kinter MT, Kehrer JP, Roberts RJ. The effects of monounsaturated and polyunsaturated fatty acids on oxygen toxicity in cultured cells. Pediatr Res 1992;32:366-72.
21. Wagner BA, Buettner GR, Burns CP. Free radical-mediated lipid peroxidation products in cells: Oxidizability is a function of cell lipid bisallylic hydrogen content. Biochemistry 1994; 33:4449-53.
22. Wagner BA, Buettner GR, Burns CP. Membrane peroxidative damage enhancement by the ether lipid class of antineoplastic agents. Cancer Res 1992;52:6045-51.
23. Shasby DM, Lind SE, Shasby SS, Goldsmith JC, Hunninghake GW. Reversible oxidant-mediated increases in albumin transfer across cultured endothelium: alterations in cell shape and calcium homeostasis. Blood 1985;65:605-14.
24. Gottlieb AI, Lowell B, Wong KKK, and Kim DW. Structure and function of the endothelial cytoskeleton. Lab Invest 1991;65:123-37.
25. Hinshaw DB, Burger JM, Armstrong BC, Hyslop PA. Mechanism of endothelial shape change in oxidant injury. J Surg Res 1989;46:339-49.
26. Hart CM, Dominguez JH, Garcia JGN. Fatty acids modulate oxidant stress and intracellular calcium in pulmonary artery endothelial cells [abstract]. Clin Res 1993;41:281.
27. Garcia JGN, Schaphorst KL. Regulation of endothelial cell gap formation and paracellular permeability. J Investig Med 1995;43:117-26.
28. Conforti G, Zanetti A, Pasquali-Ronchetti I, Quaglino Q, Neyroz P, Dejana E. Modulation of vitronectin receptor binding by membrane lipid composition. J Biol Chem 1990;265:4011-9.
29. DeCaterina R, Cybulsky MI, Clinton SK, Gimbrone MA, Libby P. The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proin-flammatory proteins in human endothelial cells. Arterioscler Thromb Vase Biol 1994;14:1829-36.
30. Bradley JR, Thiru S, Pober JS. Hydrogen peroxide-induced endothelial cell retraction is accompanied by loss of the normal spatial organization of endothelial cell adhesion molecules. Am J Pathol 1995;147:627-41.
31. Palladini G, Finardi G, Bellomo G. Disruption of actin microfilament organization by cholesterol oxides in 73/73 endothelial cells. Exp Cell Res 1996;223:72-82.
32. Parthasarathy S, Khoo JC, Miller E, Barnett J, Witzum JL, Steinberg D. Low density lipoprotein rich in oleic acid is protected against oxidative modification: implications for dietary prevention of atherosclerosis. Proc Natl Acad Sci U S A 1990;87:3894-8.
33. Reaven PS, Parthasarathy S, Grasse B, Miller E, Steinberg D, Witztum J. Effects of oleate-rich and linoleate-rich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects. J Clin Invest 1993;91:668-76.
34. Reaven PD, Grasse B J, Tribble DL. Effects of linoleateenriched and oleate enriched diets in combination with a-to-copherol on the susceptibility of LDL and LDL subfractions to oxidative modifications in humans. Arterioscler Thromb Vase Biol 1994;14:557-66.
35. Karman RJ, Garcia JGN, Hart CM. Endothelial monolayer dysfunction caused by oxidized low density lipoprotein: attenuation by oleic acid. Prostaglandins, Leukot Essen Fatty Acids (in press).