Nifedipine protects small intestine from cyclosporine-induced hemodynamic and functional impairment

Journal of Surgical Research

Volumn 69, Issue 2, 1997, Pages 295-299

  Sun, Shuching ^a,b   Greenstein, Stuart M ^a,b   Kim, Dean Y ^a   Schreiber, Thomas C ^a   Schechner, Richard S ^a   Tellis, Vivian A ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b MONTEFIORE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; NIFEDIPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFICACY; GASTROINTESTINAL TOXICITY; INTESTINE BLOOD FLOW; INTESTINE INJURY; INTRAMUSCULAR DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; VASODILATATION;

EID: 0031147771     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1997.5035     Document Type: Conference Paper

References (33)

1. 1. Murray, B. M., Paller, M. S., and Ferris, T. F. Effect of cyclosporine administration on renal hemodynamics in conscious rats. Kidney Int. 28: 76, 1985.
2. 2. Barros, E. J. G., Boim, M. A., Aizen, H., Ramoz, O. L., and Schor, N. Glomerular hemodynamics and hormonal participation on cyclosporine nephrotoxicity. Kidney Int. 32: 19, 1987.
3. 3. Dieperink, H., Leyssac, P.P., Starklint, H., Jørgensen, K. A., and Kemp, E. Antagonist capacities of nifedipine, captopril, phenoxybenzamine, prostacyclin and indomethacin on cyclosporine A induced impairment of rat renal function. Eur. J. Clin. Invest. 16: 540, 1986.
4. 4. Rooth, P., Dawidson, I., Diller, K., and Täljedal, I. B. Protection against cyclosporine-induced impairment of renal microcirculation by verapamil in mice. Transplantation 45: 433, 1988.
5. 5. Kiberd, B. A. Cyclosporine-induced renal dysfunction in human renal allografted recipients. Transplantation 48: 965, 1989.
6. 6. Greenstein, S. M., Sun, S. C., Schechner, R. S., Senitzer, D., Katz, S. M., and Tellis, V. A. Prolonged use of cyclosporine produces reversible hemodynamic and absorptive alteration in the transplanted rat small intestine. J. Surg. Res. 56: 518, 1994.
7. 7. Soward, A. L., Vanhaleweyk, G. L. J., and Serruys, P. W. The hemodynamic effects of nifedipine, verapamil and diltiazem in patients with coronary artery disease: A review. Drugs 32: 66, 1986.
8. 8. Kart, W. J., Westbroeck, D. L., MacDicken, I., and Lameizer, L. D. F. Orthotopic total small bowel transplantation in the rat. Eur. Surg. Res. 5: 81, 1973.
9. 9. Billiar, T. R., Garberoglio, C., and Schraut, W. H. Maltose absorption as an indicator of small intestinal allograft rejection. J. Surg. Res. 37: 75, 1984.
10. 10. Monaco, D. O., Wait, R. B., Friedman, A. L., and Kahng, K. U. Effects of chronic cyclosporine therapy on renal vascular reactivity in the isolated perfused rabbit kidney. Transplant. Proc. 20(Suppl. 3): 578, 1988.
11. 11. Klintmalm, G. B. G., Iwatsuki, S., and Starzl, T. E. Cyclosporine A hepatic toxicity in 66 renal allograft recipients. Transplantation 32: 488, 1981.
12. 12. Youngelman, D. F., Kahng, K. U., Dresnar, L. S., Munshi, I. A., and Wait, R. B. Cyclosporine induced alterations in renal, intrarenal, and pancreatic blood flow. Transplant. Proc. 23: 718, 1991.
13. 13. Paul, L. C., Kingma, I., ter Keurs, M. H. C., and ter Keurs, H. E. D. J. Cyclosporine impairs cardiac function in the rat. Transplant. Proc. 23: 475, 1991.
14. 14. Dawidson, I., Rooth, P., Fry, W. R., Sandor, Z., Willms, C., Coopender, L., Alway, C., and Reisch, J. Prevention of acute cyclosporine-induced renal blood flow inhibition and improved immunosuppression with verapamil. Transplantation 48: 575, 1989.
15. 15. Benigni, A., Morigi, M., Perico, N., Zoja, C., Amuchastequi, C. S., Piccinelli, A., Donadelli, R., and Remuzzi, G. The acute effect of FK 506 and cyclosporine on endothelial cell function and renal vascular resistance. Transplantation 54: 775, 1992.
16. 16. Petric, R., Freeman, D., Wallace, C., McDonald, J., Stiller, C., and Keown, P. Amelioration of experimental cyclosporine nephrotoxicity by calcium channel inhibition. Transplantation 54: 1103, 1992.
17. 17. Dieperink, H., Hansen, H. V., Kemp, M., Leyssac, P. P., Starklint, H., and Kemp, E. Antagonist capacity of felodipine on cyclosporin A nephrotoxicity in the rat. Nephrol. Dial. Transplant. 7: 1124, 1992.
18. 18. Feehally, J., Walls, J., Mistry, N., Horsburgh, T., Taylor, J., Veitch, P. S., and Bell, P. R. Dose nifedipine ameliorate cyclosporine toxicity? Br. Med. J. 295: 310, 1987.
19. 19. Carmellini, M., Salvadori, M., Di Stefano, R., Bertoni, E., Nicita, G., Rosati, A., Taddei, G., Rindi, P., Rizzo, G., and Mosca, F. Delayed graft function of cadaveric renal transplants is prevented by diltiazem. Transplant. Proc. 28: 80, 1996.
20. 20. Kazda, S. Future prospects for calcium antagonists. Drugs 48(Suppl. 1): 32, 1994.
21. 21. Van Nueten, J. M., and Vanhoutte, P. M. Improvement of tissue perfusion with inhibitors of calcium ion influx. Biochem. Pharmacol. 29: 479, 1980.
22. 22. Loutzenhiser, R., and Epstein, M. Effects of calcium antagonists on renal hemodynamics. Am. J. Physiol. 249: F619, 1985.
23. 23. Criscione, L., Nellis, P., Riniker, B., Thomann, H., and Burdet, R. Reactivity and sensitivity of mesenteric vascular beds and aortic rings of spontaneously hypertensive rats to endothelin: Effects of calcium entry blockers. Br. J. Pharmacol. 100: 31, 1990.
24. 24. Yanagisawa, M., Kurihara, H., Kimura, S., Tomobe, Y., Kobayashi, M., Ashi, M., Mitsui, Y., Yazaki, Y., Goto, K., and Masaki, T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332: 411, 1988.
25. 25. Neumayer, H., Schreiber, M., and Wagner, K. Prevention of delayed graft function by diltiazem and iloprost. Transplant. Proc. 21: 1221, 1989.
26. 26. Wagner, K., Albrecht, S., and Neumayer, H. Prevention of posttransplant acute tubular necrosis by the calcium antagonist diltiazem: A prospective randomized study. Am. J. Nephrol. 7: 287, 1987.
27. 27. Traube, M., and McCallum, R. W. Calcium-channel blockers and the gastrointestinal tract. Am. J. Gastroenterol. 79: 892, 1984.
28. 28. Jennings, W. C., and Corry, R. J. Vascular response to cyclosporine and verapamil in the rat pancreas. J. Surg. Res. 49: 341, 1990.
29. 29. Gallavan, R. H., Jr., Schwartz, A., Tabata, M., and Jacobson, E. D. A comparison of the effects of nifedipine and nitrendipine on intestinal vascular smooth muscle and intestinal blood flow (abstract). Gastroenterology 84(Part 2): 1161, 1983.
30. 30. Loutzenhiser, R., and Epstein, M. Renal hemodynamic effects of calcium antagonists. Am. J. Med. 82: 23, 1987.
31. 31. Loutzenhiser, R., and Epstein, M. Calcium antagonists and the kidney. Hosp. Pract. 15: 63, 1987.
32. 32. Sun, S. C., Greenstein, S. M., Schechner, R. S., and Tellis, V. A. Native and graft intestinal blood flow and its intramural distribution in iso-and allografted rats. Transplant. Proc. 28: 2573, 1996.
33. 2. Ann. Surg. 206: 655, 1987.