The pig as a model in liver xenotransplantation

Veterinary Research

Volumn 28, Issue 3, 1997, Pages 217-222

  Wolf, P ^a   Meyer, C ^a   Boudjema, K ^a   Kieny, R ^a   Cinqualbre, J ^a   Jaeck, D ^a   Andre E ^b   Herrenschmidt, N ^b   Azimzadeh, A ^a  

^a Fondation Transplantation   (France)

^b Fort Foch   (France)

Author keywords

Complement; Endothelial cell; Heterologous transplantation; Hyperacute rejection; Natural antibody

Indexed keywords

SUS SCROFA;

COMPLEMENT;

ANIMAL; GRAFT REJECTION; HUMAN; IMMUNOLOGY; LIVER TRANSPLANTATION; PRIMATE; REVIEW; SWINE; XENOGRAFT;

ANIMALS; COMPLEMENT SYSTEM PROTEINS; GRAFT REJECTION; HUMANS; LIVER TRANSPLANTATION; PRIMATES; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 0031137879     PISSN: 09284249     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Auchincloss H (1994) Cell-mediated xenoresponses: strong or weak? Clin Transplantation 8, 155-159
2. Bach FH, Robson SC, Ferran C, Winkler H, Millan MT, Stuhlmeier KM, Vanhove B, Blakely ML, van der Werf WJ, Hofer E, de Martin R, Hancock WW (1994) Endothelial cell activation and thromboregulation during xenoaraft rejection. Immunol Rev 141, 5-30
3. Calne RY (1970) Organ transplantation between widely disparate species. Transplant Proc 2, 550
4. Chari RS, Collins BH, Magee JC, DiMaio JM, Kirk AD, Harland RC, Mc Cann RL, Platt JL, Meyers WC (1994) Treatment of hepatic failure with ex-vivo pig-liver perfusion followed by liver transplantation. N Engl J Med 331, 234-237
5. Cooper DKC (1993) Xenografting: how great is the clinical need? Xeno 1, 25-26
6. Cozzi E, White DJG (1995) The generation of transgenic pigs as potential human donors for humans. Nature Med 1, 964-966
7. Galili U (1994) Significance of the natural human anti-Gal antibody in xenotransplantation. Xeno 2, 84-87
8. Makowka L, Cramer DV, Hoffman A, Breda M, Eiras-Hreba G, Tuso PJ, Vasunaga C, Cosenza CA, Wu GD, Chapman FA, Sher L, Podesta L (1995) The use of a pig liver xenograft for temporary support of a patient with fulminant hepatic failure. Transplantation 59, 1654-1659
9. Meyer C, Azimzadeh A, Beller JP, Kieny R, Lucchiari N, Ducros X, Boudjema K, Jaeck D, Cinqualbre J, Wolf P (1996) Extracorporal immunoadsorption of xenoreactive natural antibodies in the pig to primate model: comparison of three methods. Transplant Proc 28, 799-800
10. Platt JL, Lindman BJ, Chen H, Spitalnik SL, Bach FH (1990) Endothelial cell antigens recognized by xenoreactive natural antibodies. Transplantation 50, 817-822
11. Rieben R, Von Allmen E, Korchagina EY, Nydegger UE, Neethling FA, Kujundzic M, Koren E, Bovin NV, Cooper DKC (1995) Detection, immunoabsorption and inhibition of cytotoxic activity of anti-αGal antibodies using newly developed substances with synthetic Galα1-3Gal disaccharide epitopes. Xeno 2, 98-106
12. Sandrin MS, Fodor WL, Mouhtouris E, Osman N, Cohney S, Rollins SA, Guimette ER, Setter E, Squinto SP, McKenzie IFC (1995) Enzymatic remodelling of the carbohydrate surface of a xenogenic cell substantially reduces human antibody binding and complement-mediated cytolysis Nature Med 1, 1261-1267
13. Starzl TE, Fung J, Tzakis A, Todo S, Demetris AJ, Marino IR, Doyle H, Zeevi A, Warty V, Michaels M, Kusne S, Rudert WA, Trucco M (1993) Baboon-to-human liver transplantation. Lancet 341, 65-71
14. Taylor R (1995) A pig in a poke? Xenotransplants and infectious disease. Nature Med 1, 728-729