Molecular modelling studies of substrate binding to the lipase from Rhizomucor miehei

Journal of Computer-Aided Molecular Design

Volumn 11, Issue 3, 1997, Pages 256-264

  Yagnik, Asutosh T ^a   Littlechild, Jennifer A ^a   Turner, Nicholas J ^a,b  

^a UNIVERSITY OF EXETER   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Catalytic triad; Enantioselectivity; Oxazolinones; Protein dynamics; Transition state complex

Indexed keywords

ENZYMES; HYDROGEN BONDS; MOLECULAR MODELING; TRANSESTERIFICATION;

BIOTRANSFORMATION REACTIONS; CATALYTIC TRIAD; LIPASE ENZYME; MOLECULAR MODELING STUDIES; ORGANIC SYNTHESIS; OXAZOLINONE; PROTEIN DYNAMICS; RHIZOMUCOR MIEHEI; SUBSTRATE-BINDING; TRANSITION STATE COMPLEX;

ENANTIOSELECTIVITY;

ENZYME INHIBITOR; LIGAND; LIPOZYME; TRIACYLGLYCEROL LIPASE;

ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; ENZYMOLOGY; HYDROGEN BOND; MUCORALES; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS; X RAY DIFFRACTION;

BINDING SITES; CATALYSIS; COMPUTER SIMULATION; ENZYME INHIBITORS; HYDROGEN BONDING; LIGANDS; LIPASE; MODELS, MOLECULAR; MUCORALES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS; X-RAY DIFFRACTION;

EID: 0031134170     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007904628011     Document Type: Article

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