Inhibition of hepatitis B virus by retroviral vectors expressing antisense RNA

Journal of Viral Hepatitis

Volumn 4, Issue 3, 1997, Pages 167-174

  Ji, W ^a   Si, C W ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Antisense RNA; Gene therapy; Hepatitis B virus; Retroviral vector

Indexed keywords

ANTIVIRUS AGENT; COMPLEMENTARY RNA; HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIGEN; PROTEIN PRECURSOR;

ANIMAL; ARTICLE; CELL CULTURE; CELL LINE; CELL STRAIN 3T3; DRUG EFFECT; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETIC TRANSCRIPTION; GENETICS; HEPATITIS B VIRUS; HUMAN; MOLONEY LEUKEMIA ONCOVIRUS; MOUSE;

3T3 CELLS; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEPATITIS B CORE ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; MICE; MOLONEY MURINE LEUKEMIA VIRUS; PROTEIN PRECURSORS; RNA, ANTISENSE; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0031131802     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2893.1997.00144.x     Document Type: Article

References (14)

1. Lau JYN, Wright TL. Molecular biology and pathogenesis of hepatitis B virus. Lancet 1993; 342: 1335-1340.
2. Wright TL, Lau JYN. Clinical aspects of hepatitis B virus infection. Lancet 1993; 342: 1340-1344.
3. Goodazi G, Gross SC, Tewari A, Watabe K. Antisense oligodeoxyribonucleotides inhibit the expression of the gene for hepatitis B virus antigen. J Gen Virol 1990; 71: 3021-3025.
4. Yao Z-Q, Zhou YX, Wang AL et al. Inhibition of hepatitis B viral gene expression by antisense phosphorothioate oligodeoxynucleotides. J Viral Hep 1995; 2: 85-90.
5. Rhodes A, James W. Inhibition of heterologous strains of HIV by antisense RNA. AIDS 1991; 5: 145-151.
6. Gerlich WH, Lu X, Heerman KH. Studies on the attachment and penetration of hepatitis B virus. J Hepatol 1993; 17: S10-S14.
7. Will H, Reiser W, Weimer T et al. Replication strategy of human hepatitis B virus. J Virol 1987; 61: 904-911.
8. Lin CG, Lo SJ. Evidence for involvement of ribosomal leaky scanning mechanism in the translation of the hepatitis B viral pol gene from the viral pregenome RNA. Virology 1992; 188: 342-352.
9. Nassal M, Junker-Niepman M, Schaller H. Translation inactivation of RNA function: discrimination against a subset of genomic transcripts during hepatitis B virus nucleocapsidassembly. Cell 1990; 63: 1357-1363.
10. Dubois MF, Pourcelm C, Rousset S, Chany C, Tiollais P. Excretion of hepatitis B surface antigen particles from mouse cells transformed with cloned viral DNA. Proc Natl Acad Sci USA 1980; 77: 4549-4553.
11. Miller AD. Retroviral vectors. Curr Top Microbiol Immunol 1992; 158: 1-24.
12. Sells MA, Chen ML, Asc G. Production of hepatitis B virus in HepG2 cells transfected with cloned hepatitis B virus DNA. Proc Natl Acad Sci USA 1987; 84: 1005-1009.
13. Sambrook J, Fritsch EP, Manitis T. Molecular Cloning: A Laboratory Manual. New York: Cold Spring Harbor Laboratory Press: 1989.
14. Mosmann T. Rapid colorimetric assay for cellular growth and survival:application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.