Comparative effects of β2-adrenergic agonists on muscle waste associated with tumour growth

Cancer Letters

Volumn 115, Issue 1, 1997, Pages 113-118

  Carbó, Neus ^a   López Soriano, Joaquín ^a   Tarragó, Teresa ^a   González, Olga ^a   Llovera, Marta ^a   López Soriano, Francisco J ^a   Argilés, Josep M ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

2 agonists; Muscle waste; Tumour growth

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CLENBUTEROL; SALBUTAMOL; SALMETEROL; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; DRUG DERIVATIVE; MUSCLE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASCITES HEPATOMA; CACHEXIA; CANCER GROWTH; CONTROLLED STUDY; GASTROCNEMIUS MUSCLE; HEART MUSCLE; MALE; MUSCLE ATROPHY; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; SOLEUS MUSCLE; WHITE ADIPOSE TISSUE; ADIPOSE TISSUE; ANIMAL; BODY WEIGHT; COMPARATIVE STUDY; DRUG EFFECT; EATING; LIVER TUMOR; WISTAR RAT;

ADIPOSE TISSUE; ADRENERGIC BETA-AGONISTS; ALBUTEROL; ANIMALS; BODY WEIGHT; CACHEXIA; CLENBUTEROL; EATING; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MUSCLE PROTEINS; MUSCULAR ATROPHY; RATS; RATS, WISTAR;

EID: 0031128582     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)04718-6     Document Type: Article

References (35)

1. [1] Lawson, D.H., Richmond, A., Nixon, D.W. and Rudman, D. (1982) Metabolic approaches to cancer cachexia, Annu. Rev. Nutr., 2, 277-301.
2. [2] Morrison, S.D. (1989) Cancer cachexia. In: Influence of Tumor Development on the Host, pp. 176-213. Editor: A.L. Liotta. Kluwer, Dordrecht.
3. [3] Tisdale, M.J. (1992) Cancer cachexia, Br. J. Cancer, 63, 337-342.
4. [4] Kien, C.L. and Camitta, B.M. (1983) Increased whole-body protein turnover in children with newly diagnosed leukemia or lymphoma, Cancer Res., 43, 5592-5596.
5. [5] Kien, C.L. and Camitta, B.M. (1987) Close association of accelerated rates of whole body protein turnover (synthesis and breakdown) and energy expenditure in children with newly diagnosed acute lymphocytic leukaemia, J. Parent Ent. Nutr., 11, 129-134.
6. [6] Tessitore, L., Bonelli, G. and Baccino, F.M. (1987) Early development of protein metabolic perturbations in the liver and skeletal muscle of tumour-bearing rats, Biochem. J., 241, 153-159.
7. [7] Beck, S.A. and Tisdale, M.J. (1989) Nitrogen excretion in cancer cachexia and its modification by a high fat diet in mice, Cancer Res., 49, 3800-3804.
8. [8] Melville, S., McNurlan, M.A., Graham Calder, A. and Garlick, P.J. (1990) Increased protein turnover despite normal energy metabolism and responses to feeding in patients with lung cancer, Cancer Res., 50, 1125-1131.
9. [9] Beck, S.A., Smith, K.L. and Tisdale, M.J. (1991) Anticachectic and antitumour effect of eicosapentaenoic acid and its effect on protein turnover, Cancer Res., 51, 6089-6093.
10. [10] Tessitore, L., Costelli, P., Bonelli, G. and Baccino, F.M. (1993) Cancer cachexia, malnutrition, and tissue protein turnover in experimental animals, Arch. Biochem. Biophys., 306, 52-58.
11. [11] Moley, J.F., Morrison, S.D., Gorschboth, C.M. and Norton, J.A. (1988) Body composition changes in rats with experimental cancer cachexia: improvement with exogenous insulin, Cancer Res., 48, 2784-2787.
12. [12] Popp, M.B., Wagner, S.C., Enrione, E.B. and Brito, O.J. (1988) Host and tumor responses to varying rates of nitrogen infusion in the tumor-bearing rat, Ann. Surg., 207, 80-89.
13. [13] Shaw, J.H. and Wolfe, R.R. (1988) Whole-body protein kinetics in patients with early and advanced gastrointestinal cancer: the early response to glucose infusion and total parenteral nutrition, Surgery, 103, 148-155.
14. [14] Tayek, J.A., Istfan, N.W., Jones, C.T., Hamawy, K.J., Bistrian, B.R. and Blackburn, G.L. (1986) Influence of the Walker 256 carcinosarcoma on muscle, tumor, and whole-body protein synthesis and growth rate in the cancer-bearing rat, Cancer Res., 46, 5649-5654.
15. [15] Pain, V.M., Randall, D.P. and Garlick, P.J. (1984) Protein synthesis in liver and skeletal muscle of mice bearing an ascites tumor, Cancer Res., 44, 1054-1057.
16. [16] Lundholm, K., Ekman, D., Edstrom, S., Karlberg, I., Jagenberg, R. and Scherstén, T. (1979) Protein synthesis in liver tissue under the influence of a methyl-cholanthrene-induced sarcoma in mice, Cancer Res., 39, 4657-4661.
17. [17] Emery, P.W., Neville, A.M., Edwards, R.H.T. and Rennie, M.J. (1982) Increased myofibrillar degradation and decreased protein synthesis in tumor-bearing mice, Eur. J. Clin. Invest., 12, 10.
18. [18] Stock, M.J. and Rothwell, N.J. (1985) Effects of β -adrenergic agonists on metabolism and body composition. In: Control and Manipulation of Animal Growth, pp. 249-257, Editors: P.J. Buttery, N.B. Hayes and D.B. Lindsay. Butterworths, London.
19. [19] Yang, Y.T. and McElligot, M.A. (1989) Multiple actions of β-adrenergic agonists on skeletal muscle and adipose tissue, Biochem. J., 261, 1-10.
20. [20] Baccino, F.M., Tessitore, L., Bonelli, G. and Isidoro, C. (1986) Protein turnover states of tumour cells and host tissues in an experimental model, Biomed. Biochim. Acta, 45, 1585-1590.
21. [21] Tessitore, L., Bonelli, G., Isidore, C., Kazakova, O.V. and Baccino, F.M. (1986) Comparative studies of protein turnover regulations in tumor cells and host tissues: development and analysis of an experimental model, Toxicol. Pathol., 14, 451-456.
22. [22] Llovera, M., García-Martínez, C., Agell, N., Marzábal, M., López-Soriano, F.J. and Argilés, J.M. (1994) Ubiquitin gene expression is increased in skeletal muscle of tumour-bearing rats, FEBS Lett., 338, 311-318.
23. [23] Tessitore, L., Costelli, P. and Baccino, F.M. (1993) Humoral mediation for cancer cachexia in tumour-bearing rats, Br. J. Cancer, 67, 15-23.
24. 2-adrenergic agonist (clenbuterol) J, Clin. Invest., 95, 2367-2372.
25. [25] Maltin, C.A., Reeds, P.J., Delday, M.I., Hay, S.M., Smith, F.J. and Lobley, G.E. (1986) Inhibition and reversal of denervation-induced atrophy by the β-agonist growth promoter, clenbuterol, Biosci. Rep., 6, 811-818.
26. [26] Maltin, C.A., Hay, S.M., Delday, M.I., Reeds, P.J. and Palmer, R.M. (1989) Evidence that the hypertrophic action of clenbuterol on denervated rat muscle is not propranolol sensitive, Br. J. Pharmacol., 96, 817-822.
27. 2-adrenergic agonists on body composition and protein synthesis in the rat, Biosci. Rep., 4, 83-91.
28. [28] Rothwell, N.J. and Stock, M.J. (1985) Modification of body composition by clenbuterol in normal and dystrophic mice, Biosci. Rep., 5, 755-760.
29. 2-adrenoceptor agonist clenbuterol, Biosci. Rep., 9, 615-621.
30. [30] Carter, W.J., Dang, A.Q., Faas, F.H. and Lynch, M.E. (1991) Effects of clenbuterol on skeletal muscle mass, body composition, and recovery from surgical stress in senescent rats, Metabolism, 40, 855-860.
31. [31] Reeds, P.J., Hay, S.M., Dorward, P.M. and Palmer, R.M. (1986) Stimulation of muscle growth by clenbuterol: lack of effect on protein biosynthesis, Br. J. Nutr., 56, 249-256.
32. [32] Rodríguez-Mariscal, M., Del Barrio, A.S., Larralde, J. and Martínez, J.A. (1993) Free intracellular and protein bound amino acids in tissues as affected by a mixed β-adrenergic agonist, Experientia, 49, 308-312.
33. [33] Garber, A.J., Karl, I.E. and Kipnis, D.M. (1976) Alanine and glutamine synthesis and release. IV. β-adrenergic inhibition of amino acid release, J. Biol. Chem., 251, 851-857.
34. [34] Maltin, C.A., Delday, M.I. and Reeds, P.J. (1986) The effects of a growth promoting drug, clenbuterol, on fibre frequency and area in hindlimb muscles from young male rats, Biosci. Rep., 6, 293-299.
35. [35] Zeman, R.J., Ludemann, R., Easton, T.G. and Etlinger, J.D. (1988) Slow to fast alterations in skeletal muscle caused by clenbuterol, a β-receptor agonist, Am. J. Physiol., 254, E726-E732.