Huntington's disease: N-methyl-D-aspartate receptor coagonist glycine is increased in platelets

Experimental Neurology

Volumn 144, Issue 2, 1997, Pages 416-419

  Reilmann, Ralf ^a   Rolf, Ludger H ^a   Lange, Herwig W ^b  

^a INST OF REPRO MED OF THE UNIV   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE; N METHYL DEXTRO ASPARTIC ACID;

ADULT; AMINO ACID ANALYSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUNTINGTON CHOREA; HYPOTHESIS; MALE; PATHOGENESIS; PRIORITY JOURNAL; THROMBOCYTE;

EID: 0031128371     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1997.6428     Document Type: Article

References (26)

1. Albin R. L., Tagle D. A. Genetics and molecular biology of Huntington's disease. Trends Neurosci. 18:1995;11-14.
2. Beal M. F. Neurochemistry and the toxin models in Huntington's disease. Curr. Opin. Neurol. 7:1994;542-547.
3. Bonilla E., Prasad A. L. N., Arrieta A. Huntington's disease: Studies on brain free amino acids. Life Sci. 42:1988;1153-1158.
4. Bruyn R. P. M., Stoof J. C. The quinolinic acid hypothesis in Huntington's chorea. J. Neurol. Sci. 95:1990;29-38.
5. Budai D., Wilcox G. L., Larson A. A. Enhancement of NMDA-evoked neuronal activity by glycine in the rat spinal cord in vivo. Neurosci. Lett. 135:1992;265-268.
6. Choi D. W., Koh J. Y., Peters S. Pharmacology of glutamate neurotoxicity in cortical cell culture: Attenuation by NMDA antagonists. J. Neurosci. 8:1988;185-196.
7. DiFiglia M. Excitotoxic injury of the neostriatum: A model for Huntington's disease. Trends Neurosci. 13:1990;286-289.
8. Ferrante R. J., Kowall N. W., Cipolloni P. B., Storey E., Beal M. F. Excitotoxin lesions in primates as a model for Huntington's disease: Histologic and neurochemical characterization. Exp. Neurol. 119:1993;46-71.
9. Freese A., DiFiglia M., Koroshetz W. J., Beal M. F., Martin J. B. Characterization and mechanism of glutamate neurotoxicity in primary striatal cultures. Brain Res. 521:1990;254-264.
10. Hartmann J., Ransmayr G., Riederer P. The glycine binding site of the NMDA receptor: Involvement in neurodegeneration and new approach for neuroprotection. J. Neural Transm. 43:1994;53-57.
11. Johnson J. W., Ascher P. Glycine potentiates the NMDA response in culture mouse brain neurons. Nature. 325:1987;529-531.
12. Kemp J. A., Foster A. C., Leeson P. D., Priestley T., Tidgett R., Iversen L. L., Woodruff G. N. 7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of theND. Proc. Natl. Acad. Sci. USA. 85:1988;6547-6550.
13. Kemp J. A., Leeson P. D. The glycine site of the NMDA receptor - Five years on. Trends Pharm. Sci. 14:1993;20-25.
14. Kowall N. W., Ferrante R. J., Martin J. B. Patterns of cell loss in Huntington's disease. Trends Neurosci. 10:1987;24-29.
15. 2+. Acta Neurobiol. Exp. 52:1992;83-91.
16. McGeer E. G., McGeer P. L. Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids. Nature. 263:1976;517-518.
17. Muir K. W., Lees K. R. Clinical experience with excitatory amino acid antagonist drugs. Stroke. 26:1995;503-513.
18. Nicoli F., Vion-Dury J., Maloteaux J. M., Delwaide C., Confort-Gouny S., Sciaky M., Cozzone P. J. CSF and serum metabolic profile of patients with Huntington's chorea: A study by high resolution proton NMR spectroscopy and HPLC. Neurosci. Lett. 154:1993;47-51.
19. Oepen G., Cramer H., Bernasconi R., Martin P. Huntington's disease - Imbalance of free amino acids in the cerebrospinal fluid of patients and offsprings at-risk. Arch. Psychiatr. Nervenkr. 231:1982;131-140.
20. Perry T. L., Hansen S., Diamond S., Stedman D. Plasma-aminoacid levels in Huntington's chorea. Lancet. 1:1969;806-808.
21. Pletscher A. Platelets as models: Use and limitations. Experientia. 44:1988;152-155.
22. Reilmann R., Rolf L. H., Lange H. W. Huntington's disease: The neuroexcitotoxin aspartate is increased in platelets and decreased in plasma. J. Neurol. Sci. 127:1994;48-53.
23. Rothman S. M., Olney J. W. Excitotoxicity and the NMDA receptor. Trends Neurosci. 10:1987;299-302.
24. Thomson A. M., Walker V. E., Flynn D. M. Glycine enhances NMDA-receptor mediated synaptic potentials in neocortical slices. Nature. 338:1989;422-424.
25. Wallis R. A., Panizzon K. L., Nolan J. P. Glycine-induced CA1 excitotoxicity in the rat hippocampal slice. Brain Res. 685:1995;225-235.
26. Warner D. S., Martin H., Ludwig P., McAllister A., Keana J. P., Weber E. In vivo models of cerebral ischemia: Effects of parenterally administered NMDA receptor glycine site antagonists. J. Cereb. Blood Flow Matab. 15:1995;188-196.