Genomic organization of the human KAI1 metastasis-suppressor gene

Genomics

Volumn 41, Issue 1, 1997, Pages 25-32

  Dong, Jin Tang ^a   Isaacs, William B ^a   Barrett, J Carl ^b   Isaacs, John T ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; BINDING SITE; CANCER INHIBITION; DNA STRUCTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRON; METASTASIS INHIBITION; MOLECULAR EVOLUTION; MUTATION RATE; PRIORITY JOURNAL; PROSTATE CANCER; REGULATORY MECHANISM; SUPPRESSOR GENE; TUMOR SUPPRESSOR GENE;

EID: 0031128066     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1997.4618     Document Type: Article

References (43)

1. Adachi, M., Taki, T., Ieki, Y., Huang, C. L., Higashiyama, M., and Miyake, M. (1996). Correlation of KAI1/CD82 gene expression with good prognosis in patients with non-small cell lung cancer. Cancer Res. 56: 1751-1755.
2. Aissani, B., and Bernardi, G. (1991). CpG islands: Features and distribution in the genomes of vertebrates. Gene 106: 173-183.
3. Andria, M. L., Hsieh, C. L., Oren, R., Francke, U., and Levy, S. (1991). Genomic organization and chromosomal localization of the TAPA-1 gene. J. Immunol. 147: 1030-1036.
4. Anton, E. S., Hadjiargyrou, M., Patterson, P. H., and Matthew, W. D. (1995). CD9 plays a role in Schwann cell migration in vitro. J. Neurosci. 15: 584-595.
5. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (1989). "Current Protocols in Molecular Biology," Wiley, New York.
6. Bell, G. M., Seaman, W. E., Niemi, E. C., and Imboden, J. B. (1992). The OX-44 molecule couples to signaling pathways and is associated with CD2 on rat T lymphocytes and a natural killer cell line. J. Exp. Med. 175: 527-536.
7. Berditchevski, F., Zutter, M. M., and Hemler, M. E. (1996). Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (tm4 proteins). Mol. Biol. Cell 7: 193-207.
8. Bird, A. P. (1986). CpG-rich islands and the function of DNA methylation. Nature 321: 209-213.
9. Boismenu, R., Rhein, M., Fischer, W. H., and Havran, W. L. (1996). A role for CD81 in early T cell development. Science 271: 198-200.
10. Counts, J. L., and Goodman, J. I. (1995). Alterations in DNA methylation may play a variety of roles in carcinogenesis. Cell 83: 13-15.
11. Donaldson, L. F., McQueen, D. S., and Seckl, J. R. (1995). Induction of transcription factor AP2 mRNA expression in rat primary afferent neurons during acute inflammation. Neurosci. Lett. 196: 181-184.
12. Dong, J.-T., Lamb, P. W., Rinker-Schaeffer, C. W., Vukanovic, J., Ichikawa, T., Isaacs, J. T., and Barrett, J. C. (1995). KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2. Science 268: 884-886.
13. Dong, J.-T., Suzuki, H., Pin, S. S., Bova, G. S., Schalken, J. A., Isaacs, W. B., Barrett, J. C., and Isaacs, J. T. (1996). Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss. Cancer Res. 56: 4387-4390.
14. Engel, P., and Tedder, T. F. (1994). New CD from the B cell section of the Fifth International Workshop on Human Leukocyte Differentiation Antigens. Leuk. Lymphoma 13(Suppl. 1): 61-64.
15. Faisst, S., and Meyer, S. (1992). Compilation of vertebrate-encoded transcription factors. Nucleic Acids Res. 20: 3-26.
16. Gardiner-Garden, M., and Frommer, M. (1987). CpG islands in vertebrate genomes. J. Mol. Biol. 196: 261-282.
17. Gaugitsch, H. W., Hofer, E., Huber, N. E., Schnabl, E., and Baumruker, T. (1991). A new superfamily of lymphoid and melanoma cell proteins with extensive homology to Schistosoma mansoni antigen Sm23. Eur. J. Immunol. 21: 377-383.
18. Gil, M. L., Vita, N., Lebel-Binay, S., Miloux, B., Chalon, P., Kaghad, M., Marchiol-Fournigault, C., Conjeaud, H., Caput, D., Ferrara, P., Fradelizi, D., and Quillet-Mary, A. (1992). A member of the tetra spans transmembrane protein superfamily is recognized by a monoclonal antibody raised against an HLA class I-deficient, lymphokine-activated killer-susceptible, B lymphocyte line: Cloning and preliminary functional studies. J. Immunol. 148: 2826-2833.
19. Hadjiargyrou, M., and Patterson, P. H. (1995). An anti-CD9 monoclonal antibody promotes adhesion and induces proliferation of Schwann cells in vitro. J. Neurosci. 15: 574-583.
20. Hasegawa, H., Utsunomiya, Y., Kishimoto, K., Yanagisawa, K., and Fujita, S. (1996). SFA-1, a novel cellular gene induced by human T-cell leukemia virus type 1, is a member of the transmembrane 4 superfamily. J. Virol. 70: 3258-3263.
21. Horejsi, V., and Vlcek, C. (1991). Novel structurally distinct family of leucocyte surface glycoproteins including CD9, CD37, CD53 and CD63. FEBS Lett. 288: 1-4.
22. Hotta, H., Miyamoto, H., Hara, I., Takahashi, N., and Homma, M. (1992). Genomic structure of the ME491/CD63 antigen gene and functional analysis of the 5′-flanking regulatory sequences. Biochem. Biophys. Res. Commun. 185: 436-442.
23. Ikeyama, S., Koyama, M., Yamaoko, M., Sasada, R., and Miyake, M. (1993). Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA. J. Exp. Med. 177: 1231-1237.
24. Imai, T., Fukudome, K., Takagi, S., Nagira, M., Furuse, M., Fukuhara, N., Nishimura, M., Hinuma, Y., and Yoshie, O. (1992). C33 antigen recognized by monoclonal antibodies inhibitory to human T cell leukemia virus type 1-induced syncytium formation is a member of a new family of transmembrane proteins including CD9, CD37, CD53, and CD63. J. Immunol. 149: 2879-2886.
25. Jankowski, S. A., De Jong, P., and Meltzer, P. S. (1995). Genomic structure of SAS, a member of the transmembrane 4 superfamily amplified in human sarcomas. Genomics 25: 501-506.
26. Korinek, V., and Horejsi, V. (1993). Genomic structure of the human CD53 gene. Immunogenetics 38: 272-279.
27. Leask, A., Byrne, C., and Fuchs, E. (1991). Transcription factor AP2 and its role in epidermal-specific gene expression. Proc. Natl. Acad. Sci. USA 88: 7948-7952.
28. Lebel-Binay, S., Gil, M. L., Lagaudriere, C., Miloux, B., Marchiol-Fournigault, C., Quillet-Mary, A., Lopez, M., Fradelizi, D., and Conjeaud, H. (1994). Further characterization of CD82/IA4 antigen (type III surface protein): An activation/differentiation marker of mononuclear cells. Cell. Immunol. 154: 468-483.
29. Magnaldo, T., Vidal, R. G., Ohtsuki, M., Freedberg, I. M., and Blumenberg, M. (1993). On the role of AP2 in epithelial-specific gene expression. Gene Expression 3: 307-315.
30. Masellis-Smith, A., and Shaw, A. R. (1994). CD9-regulated adhesion: Anti-CD9 monoclonal antibody induces pre-B cell adhesion to bone marrow fibroblasts through de novo recognition of fibronectin. J. Immunol. 152: 2768-2777.
31. Nagira, M., Imai, T., Ishikawa, I., Uwabe, K. I., and Yoshie, O. (1994). Mouse homologue of C33 antigen (CD82), a member of the transmembrane 4 superfamily: Complementary DNA, genomic structure, and expression. Cell. Immunol. 157: 144-157.
32. Nojima, Y., Hirose, T., Tachibana, K., Tanaka, T., Shi, L., Doshen, J., Freeman, G. J., Schlossman, S. F., and Morimoto, C. (1993). The 4F9 antigen is a member of the tetra spans transmembrane protein family and functions as an accessory molecule in T cell activation and adhesion. Cell. Immunol. 152: 249-260.
33. Oren, R., Takahashi, S., Doss, C., Levy, R., and Levy, S. (1990). TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins. Mol. Cell. Biol. 10: 4007-4015.
34. Radford, K. J., Mallesch, J., and Hersey, P. (1995). Suppression of human melanoma cell growth and metastasis by the melanoma-associated antigen CD63 (ME491). Int. J. Cancer 62: 631-635.
35. Radford, K. J., Thorne, R. F., and Hersey, P. (1996). CD63 associates with transmembrane 4 superfamily members, CD9 and CD81, and with beta-1 integrins in human melanoma. Biochem. Biophys. Res. Commun. 222: 13-18.
36. Rubinstein, E., Benoit, P., Billard, M., Plaisance, S., Prenant, M., Uzan, G., and Boucheix, C. (1993). Organization of the human CD9 gene. Genomics 16: 132-138.
37. Saffer, J. D., Jackson, S. P., and Annarella, M. B. (1991). Developmental expression of Sp1 in the mouse. Mol. Cell. Biol. 11: 2189-2199.
38. Schmid, C. W., and Jelinek, W. R. (1982). The Alu family of dispersed repetitive sequences. Science 216: 1065-1070.
39. Sehgal, A., Patil, N., and Chao, M. (1988). A constitutive promoter directs expression of the nerve growth factor receptor gene. Mol. Cell. Biol. 8: 3160-3167.
40. Wei, L. L., Yang, X., Phillips, K., Weissman, B. E., and Welch, D. R. (1996). Analysis of KAI-1 mRNA expression in human breast cancer cell lines. Proc. Am. Assoc. Cancer Res. 37: 76.
41. Wice, B. M., and Gordon, J. I. (1995). A tetraspan membrane glycoprotein produced in the human intestinal epithelium and liver that can regulate cell density-dependent proliferation. J. Biol. Chem. 270: 21907-21918.
42. Wright, M. D., Rochelle, J. M., Tomlinson, M. G., Seldin, M. F., and Williams, A. F. (1993). Gene structure, chromosomal localization, and protein sequence of mouse CD53 (Cd53): Evidence that the transmembrane 4 superfamily arose by gene duplication. Int. Immunol. 5: 209-216.
43. Wright, M. D., and Tomlinson, M. G. (1994). The ins and outs of the transmembrane 4 superfamily. Immunol. Today 15: 588-594.