A defective EGF-receptor in waved-2 mice attenuates intestinal adaptation

Journal of Surgical Research

Volumn 69, Issue 1, 1997, Pages 76-80

  Helmrath, Michael A ^b   Erwin, Christopher R ^b   Warner, Brad W ^a,b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR;

ANASTOMOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CELL PROLIFERATION; CONFERENCE PAPER; CRYPT CELL; HYPOTHESIS; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN CONTENT; SIGNAL TRANSDUCTION; SMALL INTESTINE RESECTION;

EID: 0031127628     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1997.5033     Document Type: Conference Paper

References (27)

1. 1. Kelly, D., McFadyen, M., King, T. P., and Morgan, P. J. Characterization and autoradiographic localization of the epidermal growth factor receptor in the jejunum of neonatal and weaned pigs. Reprod. Fertil. Dev. 4: 183, 1992.
2. 2. Scheving, L. A., Shiurba, R. A., Nguyen, T. D., and Gray, G. M. Epidermal growth factor receptor of the intestinal enterocyte. Localization to laterobasal but not brush border membrane. J. Biol. Chem. 264: 1735, 1989.
3. 3. Thompson, J. F. Specific receptors for epidermal growth factor in rat intestinal microvillus membranes. Am. J. Physiol. 254: G429, 1988.
4. 4. Alison, M. R., and Sarraf, C. E. The role of growth factors in gastrointestinal cell proliferation. Cell Biol. Int. 18: 1, 1994.
5. 5. Goodlad, R. A., Gregory, H., and Wright, N. A. Is polyamine synthesis involved in the proliferative response of the intestinal epithelium to urogastrone-epidermal growth factor? Clin. Sci. 76: 595, 1989.
6. 6. Al-Nafussi, A. I., and Wright, N. A. The effect of epidermal growth factor (EGF) on cell proliferation of the gastrointestinal mucosa in rodents. Virchows Arch. B: Cell Pathol. 40: 63, 1982.
7. 7. Chaet, M. S., Arya, G., Ziegler, M. M., and Warner, B. W. Epidermal growth factor enhances intestinal adaptation after massive small bowel resection. J. Pediatr. Surg. 29: 1035, 1994.
8. 8. Read, L. C., Ford, W. D., Filsell, O. H., McNeil, J., and Ballard, F. J. Is orally-derived epidermal growth factor beneficial following premature birth or intestinal resection? Endocrinol. Exp. 20: 199, 1986.
9. 9. Swaniker, F., Guo, W., Fonkalsrud, E. W., and Diamond, J. The effect of epidermal growth factor on mucosal function after ileal resection. J. Surg. Res. 58: 565, 1995.
10. 10. O'Loughlin, E., Winter, M., Shun, A., Hardin, J. A., and Gall, D. G. Structural and functional adaptation following jejunal resection in rabbits: Effect of epidermal growth factor. Gastroenterology 107: 87, 1994.
11. 11. Goodlad, R. A., Savage, A. P., Lenton, W., Ghatei, M. A., Gregory, H., Bloom, S. R., and Wright, N. A. Does resection enhance the response of the intestine to urogastrone-epidermal growth factor in the rat? Clin. Sci. 75: 121, 1988.
12. 12. Donaldson, R. W., and Cohen, S. Epidermal growth factor stimulates tyrosine phosphorylation in the neonatal mouse: Association of a M(r) 55,000 substrate with the receptor. Proc. Nat. Acad. Sci. U.S.A. 89: 8477, 1992.
13. 13. Ullrich, A., and Schlessinger, J. Signal transduction by receptors with tyrosine kinase activity. Cell 61: 203, 1990.
14. 14. Luetteke, N. C., Phillips, H. K., Qiu, T. H., Copeland, N. G., Earp, H. S., Jenkins, N. A., and Lee, D. C. The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase. Genes Dev. 8: 399, 1994.
15. 15. Fowler, K. J., Walker, F., Alexander, W., Hibbs, M. L., Nice, E. C., Bohmer, R. M., Mann, G. B., Thumwood, C., Maglitto, R., Danks, J. A., et al. A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation. Proc. Nat. Acad. Sci. U.S.A. 92: 1465, 1995.
16. 16. Helmrath, M. A., VanderKolk, W. E., Can, G., Erwin, C. R., and Warner, B. W. Intestinal adaptation following massive small bowel resection in the mouse. J. Am. Coll. Surg. 183: 441, 1996.
17. 17. Burton, K. A study of the conditions and mechanism of the diphenylamine reaction for the calorimetric estimation of deoxyribonucleic acid. Biochem. J. 62: 315, 1956.
18. 18. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265, 1951.
19. 19. Keeler, C. E. A second rexoid coat character in the house mouse. J. Hered. 26: 189, 1935.
20. 20. Sibilia, M., and Wagner, E. F. Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 269: 234, 1995.
21. 21. Threadgill, D. W., Dlugosz, A. A., Hansen, L. A., Tennenbaum, T., Lichti, U., Yee, D., LaMantia, C., Mourton, T., Herrup, K., Harris, R. C., et al. Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype. Science 269: 230, 1995.
22. 22. Schlessinger, J. Signal transduction by allosteric receptor oligomerization. (Review). Trends Biochem Sci. 13: 443, 1988.
23. 23. Spivak-Kroizman, T., Rotin, D., Pinchasi, D., Ullrich, A., Schlessinger, J., and Lax, I. Heterodimerization of c-erbB2 with different epidermal growth factor receptor mutants elicits stimulatory or inhibitory responses. J. Biol. Chem. 267: 8056, 1992.
24. 24. Malo, C., and Menard, D. Influence of epidermal growth factor on the development of suckling mouse intestinal mucosa. Gastroenterology 83: 28, 1982.
25. 25. O'Loughlin, E. V., Chung, M., Hollenberg, M., Hayden, J., Zahavi, I., and Gall, D. G. Effect of epidermal growth factor on ontogeny of the gastrointestinal tract. Am. J. Physiol. 249: G674, 1985.
26. 26. Foltzer-Jourdainne, C. and Raul, F. Effect of epidermal growth factor on the expression of digestive hydrolases in the jejunum and colon of newborn rats. Endocrinology 127: 1763, 1990.
27. 27. Oka, Y., Ghishan, F. K., Greene, H. L., and Orth, D. N. Effect of mouse epidermal growth factor/urogastrone on the functional maturation of rat intestine. Endocrinology 112: 940, 1983.