메뉴 건너뛰기




Volumn 9, Issue 2, 1997, Pages 135-144

Do CTL kill target cells by inducing apoptosis?

Author keywords

Apoptosis; Cytotoxicity; Granzyme; Lysis

Indexed keywords

ENZYME INHIBITOR;

EID: 0031127455     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1006/smim.1997.0063     Document Type: Article
Times cited : (36)

References (57)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • 1. Kerr JFR, Wyllie AH, Currie AR (1972) Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 2
    • 0029025515 scopus 로고
    • Apoptosis: O death, where is thy sting?
    • 2. Henkart PA (1995) Apoptosis: O death, where is thy sting? J Immunol 154:4905-4908
    • (1995) J Immunol , vol.154 , pp. 4905-4908
    • Henkart, P.A.1
  • 3
    • 0028147070 scopus 로고
    • Programmed cell death in Caenorhabditis elegan
    • 3. Hengartner MO, Horvitz HR (1994) Programmed cell death in Caenorhabditis elegan. Curr Opin Genet Dev 4:581-586
    • (1994) Curr Opin Genet Dev , vol.4 , pp. 581-586
    • Hengartner, M.O.1    Horvitz, H.R.2
  • 4
    • 0029880987 scopus 로고    scopus 로고
    • The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease
    • 4. Xue D, Shaham S, Horvitz HR (1996) The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease. Genes Dev 10:1073-1083
    • (1996) Genes Dev , vol.10 , pp. 1073-1083
    • Xue, D.1    Shaham, S.2    Horvitz, H.R.3
  • 5
    • 0029956641 scopus 로고    scopus 로고
    • Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
    • 5. Kuida K, Zheng TS, Na S et al (1996) Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384:368-372
    • (1996) Nature , vol.384 , pp. 368-372
    • Kuida, K.1    Zheng, T.S.2    Na, S.3
  • 6
    • 0029664296 scopus 로고    scopus 로고
    • ICE family proteases: Mediators of all apoptotic cell death?
    • Review
    • 6. Henkart PA (1996) ICE family proteases: mediators of all apoptotic cell death? (Review). Immunity 4:195-201
    • (1996) Immunity , vol.4 , pp. 195-201
    • Henkart, P.A.1
  • 7
    • 0029978182 scopus 로고    scopus 로고
    • Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptotis
    • 7. Enari M, Talanian RV, Wong WW, Nagata S (1996) Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptotis. Nature 380:723-726
    • (1996) Nature , vol.380 , pp. 723-726
    • Enari, M.1    Talanian, R.V.2    Wong, W.W.3    Nagata, S.4
  • 8
    • 0029670910 scopus 로고    scopus 로고
    • CPP32/ apopain is a key interleukin-1-beta converting enzyme-like protease involved in Fas-mediated apoptosis
    • 8. Schlegel J, Peters I, Orrenius S et al (1996) CPP32/ apopain is a key interleukin-1-beta converting enzyme-like protease involved in Fas-mediated apoptosis. J Biol Chem 271:1841-1844
    • (1996) J Biol Chem , vol.271 , pp. 1841-1844
    • Schlegel, J.1    Peters, I.2    Orrenius, S.3
  • 9
    • 0029890823 scopus 로고    scopus 로고
    • Apopain/ CPP32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death
    • 9. Casciola-Rosen L, Nicholson DW, Chong T et al (1996) Apopain/ CPP32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death. J Exp Med 183:1957-1964
    • (1996) J Exp Med , vol.183 , pp. 1957-1964
    • Casciola-Rosen, L.1    Nicholson, D.W.2    Chong, T.3
  • 10
    • 0028149332 scopus 로고
    • Apoptotic cell death induced by intracellular proteolysis
    • 10. Williams MS, Henkart PA ( 1994) Apoptotic cell death induced by intracellular proteolysis. J Immunol 153:4247-4255
    • (1994) J Immunol , vol.153 , pp. 4247-4255
    • Williams, M.S.1    Henkart, P.A.2
  • 11
    • 0030472889 scopus 로고    scopus 로고
    • Different ICE-family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli
    • 11. Sarin A, Wu M-L, Henkart PA (1996) Different ICE-family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli. J Exp Med 184:2445-2450
    • (1996) J Exp Med , vol.184 , pp. 2445-2450
    • Sarin, A.1    Wu, M.-L.2    Henkart, P.A.3
  • 14
    • 0028973302 scopus 로고
    • An interleukin-1-beta converting enzyme-like protease is a common mediator of apoptosis in thymocytes
    • 14. Fearnhead HO, Dinsdale D, Cohen GM (1995) An interleukin-1-beta converting enzyme-like protease is a common mediator of apoptosis in thymocytes. FEBS Lett 375:283-288
    • (1995) FEBS Lett , vol.375 , pp. 283-288
    • Fearnhead, H.O.1    Dinsdale, D.2    Cohen, G.M.3
  • 15
    • 0029092507 scopus 로고
    • Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro
    • 15. Milligan CE, Prevette D, Yaginuma H et al (1995) Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro. Neuron 15:385-393
    • (1995) Neuron , vol.15 , pp. 385-393
    • Milligan, C.E.1    Prevette, D.2    Yaginuma, H.3
  • 16
    • 0030060075 scopus 로고    scopus 로고
    • Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER
    • 16. Pronk GJ, Ramer K, Amiri P, Williams LT (1996) Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER. Science 271:808-810
    • (1996) Science , vol.271 , pp. 808-810
    • Pronk, G.J.1    Ramer, K.2    Amiri, P.3    Williams, L.T.4
  • 17
    • 0028841537 scopus 로고
    • An ICE-like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP 1 cells
    • 17. Zhu HJ, Fearnhead HO, Cohen GM (1995) An ICE-like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP 1 cells. FEBS Lett 374:303-308
    • (1995) FEBS Lett , vol.374 , pp. 303-308
    • Zhu, H.J.1    Fearnhead, H.O.2    Cohen, G.M.3
  • 18
    • 0029853199 scopus 로고    scopus 로고
    • Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death
    • 18. Rodriguez I, Matsuura K, Ody C, Nagata S, Vassalli P (1996) Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death. J Exp Med 184:2067-2072
    • (1996) J Exp Med , vol.184 , pp. 2067-2072
    • Rodriguez, I.1    Matsuura, K.2    Ody, C.3    Nagata, S.4    Vassalli, P.5
  • 19
    • 0030338359 scopus 로고    scopus 로고
    • Inhibition of cysteine and serine proteinases by the cowpox virus serpin CrmA
    • 19. Komiyama T, Quan LT, Salvesen GS (1996) Inhibition of cysteine and serine proteinases by the cowpox virus serpin CrmA. AdvExp Med Biol 389:173-176
    • (1996) Advexp Med Biol , vol.389 , pp. 173-176
    • Komiyama, T.1    Quan, L.T.2    Salvesen, G.S.3
  • 20
    • 0028817947 scopus 로고
    • Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35
    • 20. Bump NJ, Hackett M, Hugunin M et al (1995) Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35. Science 269:1885-1888
    • (1995) Science , vol.269 , pp. 1885-1888
    • Bump, N.J.1    Hackett, M.2    Hugunin, M.3
  • 21
    • 0027430789 scopus 로고
    • Expression of the baculovirus p35 gene inhibits mammalian neural cell death
    • 21. Rabizadeh S, LeCount DJ, Friesen PD, Bredesen DE (1993) Expression of the baculovirus p35 gene inhibits mammalian neural cell death. J Neurochem 61:2318-2321
    • (1993) J Neurochem , vol.61 , pp. 2318-2321
    • Rabizadeh, S.1    LeCount, D.J.2    Friesen, P.D.3    Bredesen, D.E.4
  • 22
    • 0028096991 scopus 로고
    • Suppression of apoptosis in insect cells stably transfected with baculovirus p35: Dominant interference by N-terminal sequences p35 (1-76)
    • 22. Cartier JL, Hershberger PA, Friesen PD (1994) Suppression of apoptosis in insect cells stably transfected with baculovirus p35: Dominant interference by N-terminal sequences p35 (1-76). J. Virol 68:7728-7737
    • (1994) J. Virol , vol.68 , pp. 7728-7737
    • Cartier, J.L.1    Hershberger, P.A.2    Friesen, P.D.3
  • 23
    • 0028141705 scopus 로고
    • Expression of baculovirus p35 prevents cell death in Drosophila
    • 23. Hay BA, Wolff T, Rubin GM (1994) Expression of baculovirus p35 prevents cell death in Drosophila. Development 120:2121-2129
    • (1994) Development , vol.120 , pp. 2121-2129
    • Hay, B.A.1    Wolff, T.2    Rubin, G.M.3
  • 24
    • 0027990727 scopus 로고
    • Control of programmed cell death by the baculovirus genes p35 and iap
    • 24. Clem RJ, Miller LK (1994) Control of programmed cell death by the baculovirus genes p35 and iap. Mol Cell Biol 14:5212-5222
    • (1994) Mol Cell Biol , vol.14 , pp. 5212-5222
    • Clem, R.J.1    Miller, L.K.2
  • 25
    • 0028271740 scopus 로고
    • Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans
    • 25. Sugimoto A, Friesen PD, Rothman JH (1994) Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans. EMBO J 13:2023-2028
    • (1994) EMBO J , vol.13 , pp. 2023-2028
    • Sugimoto, A.1    Friesen, P.D.2    Rothman, J.H.3
  • 26
    • 0017681718 scopus 로고
    • The mechanism of T cell mediated cytotoxicity. V Morphological studies by electron microscopy
    • 26. Sanderson CJ, Glaueret AM (1977) The mechanism of T cell mediated cytotoxicity. V Morphological studies by electron microscopy. Proc Roy Soc Lond 198:315-323
    • (1977) Proc Roy Soc Lond , vol.198 , pp. 315-323
    • Sanderson, C.J.1    Glaueret, A.M.2
  • 27
    • 0018843454 scopus 로고
    • Mechanisms of immune lysis. I. Physiological distinction between target cell death mediated by cytotoxicT lymphocytes and antibody plus complement
    • 27. Russell JH, Masakowski VR, Dobos CR (1980) Mechanisms of immune lysis. I. Physiological distinction between target cell death mediated by cytotoxicT lymphocytes and antibody plus complement. J Immunol 124:1100-1105
    • (1980) J Immunol , vol.124 , pp. 1100-1105
    • Russell, J.H.1    Masakowski, V.R.2    Dobos, C.R.3
  • 28
    • 0011123295 scopus 로고
    • Endogenous endonuclease-induced DNA fragmentation: An early event in cell-mediated cytolysis
    • 28. Duke RC, Chervenak R, Cohen JJ (1983) Endogenous endonuclease-induced DNA fragmentation: An early event in cell-mediated cytolysis. Proc Natl Acad Sci USA 80:6361-6365
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 6361-6365
    • Duke, R.C.1    Chervenak, R.2    Cohen, J.J.3
  • 29
    • 0022308091 scopus 로고
    • Mechanism of lymphocyte-mediated cytotoxicity
    • 29. Henkart PA (1985) Mechanism of lymphocyte-mediated cytotoxicity. Annu Rev Immunol 3:31-58
    • (1985) Annu Rev Immunol , vol.3 , pp. 31-58
    • Henkart, P.A.1
  • 30
    • 0028013642 scopus 로고
    • Susceptibility to cytotoxic T lymphocyte-induced apoptosis is a function of the proliferative status of the target
    • 30. Nishioka WK, Welsh RM (1994) Susceptibility to cytotoxic T lymphocyte-induced apoptosis is a function of the proliferative status of the target. J Exp Med 179:769-774
    • (1994) J Exp Med , vol.179 , pp. 769-774
    • Nishioka, W.K.1    Welsh, R.M.2
  • 31
    • 0025868622 scopus 로고
    • Cytotoxic T lymphocytes induce different types of DNA damage in target cells of different origins
    • 31. Sellins KS, Cohen JJ (1991) Cytotoxic T lymphocytes induce different types of DNA damage in target cells of different origins. J Immunol 147:795-803
    • (1991) J Immunol , vol.147 , pp. 795-803
    • Sellins, K.S.1    Cohen, J.J.2
  • 32
    • 0026645504 scopus 로고
    • Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes
    • 32. Ucker DS, Obermiller PS, Eckhart W, Apgar JR, Berger NA, Meyers J (1992) Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes. Mol Cell Biol 12:3060-3069
    • (1992) Mol Cell Biol , vol.12 , pp. 3060-3069
    • Ucker, D.S.1    Obermiller, P.S.2    Eckhart, W.3    Apgar, J.R.4    Berger, N.A.5    Meyers, J.6
  • 33
    • 0025973806 scopus 로고
    • A noncytotoxic mast cell tumor line exhibits potent IgE-dependent cytotoxicity after transfection with the cytolysin/ perforin gene
    • 33. Shiver JW, Henkart PA (1991) A noncytotoxic mast cell tumor line exhibits potent IgE-dependent cytotoxicity after transfection with the cytolysin/ perforin gene. Cell 62:1174-1181
    • (1991) Cell , vol.62 , pp. 1174-1181
    • Shiver, J.W.1    Henkart, P.A.2
  • 34
    • 0028967988 scopus 로고
    • Synergistic roles of granzymes A and B in mediating target cell death by RBL mast cell tumors also expressing cytlysin/ perforin
    • 34. Nakajima H, Park HL, Henkart PA (1995) Synergistic roles of granzymes A and B in mediating target cell death by RBL mast cell tumors also expressing cytlysin/ perforin. J Exp Med 181:1037-1046
    • (1995) J Exp Med , vol.181 , pp. 1037-1046
    • Nakajima, H.1    Park, H.L.2    Henkart, P.A.3
  • 35
    • 0028938366 scopus 로고
    • The target cell nucleus is not required for cell-mediated granzyme-or Fas-based cytotoxicity
    • 35. Nakajima H, Golstein P, Henkart PA (1995) The target cell nucleus is not required for cell-mediated granzyme-or Fas-based cytotoxicity. J Exp Med 181:1905-1909
    • (1995) J Exp Med , vol.181 , pp. 1905-1909
    • Nakajima, H.1    Golstein, P.2    Henkart, P.A.3
  • 36
    • 0029099845 scopus 로고
    • Activation of the apoptotic protease CPP32 by cytotoxic T cell-derived granzyme B
    • 36. Darmon AJ, Nicholson DW, Bleackley RC (1995) Activation of the apoptotic protease CPP32 by cytotoxic T cell-derived granzyme B. Nature 377:446-448
    • (1995) Nature , vol.377 , pp. 446-448
    • Darmon, A.J.1    Nicholson, D.W.2    Bleackley, R.C.3
  • 37
    • 0029892244 scopus 로고    scopus 로고
    • Proteolytic activation of the cell death protease Yama/ CPP32 by granzyme B
    • 37. Quan LT, Tewari M, O'Rourke K et al (1996) Proteolytic activation of the cell death protease Yama/ CPP32 by granzyme B. Proc Natl Acad Sci USA 93:1972-1976
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1972-1976
    • Quan, L.T.1    Tewari, M.2    O'Rourke, K.3
  • 38
    • 9344261615 scopus 로고    scopus 로고
    • The cytotoxic cell protease granzyme b initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/ CED-3 family protease, CPP-32, via a novel two-step mechanism
    • 38. Martin SJ, Amarante-Mendes GP, Shi L et al (1996) The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/ CED-3 family protease, CPP-32, via a novel two-step mechanism. EMBO J 15:2407-2417
    • (1996) EMBO J , vol.15 , pp. 2407-2417
    • Martin, S.J.1    Amarante-Mendes, G.P.2    Shi, L.3
  • 40
    • 0030198505 scopus 로고    scopus 로고
    • Cytotoxic T cell-derived granzyme B activates the apoptotic protease ICE-LAP3
    • 40. Chinnaiyan AM, Hanna WL, Orth K et al (1996) Cytotoxic T cell-derived granzyme B activates the apoptotic protease ICE-LAP3. Curr Biol 6:897-899
    • (1996) Curr Biol , vol.6 , pp. 897-899
    • Chinnaiyan, A.M.1    Hanna, W.L.2    Orth, K.3
  • 41
    • 0030008812 scopus 로고    scopus 로고
    • ICE-LAP6, a novel member of the ICE/ Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B
    • 41. Duan HJ, Orth K, Chinnaiyan AM et al (1996) ICE-LAP6, a novel member of the ICE/ Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B. J Biol Chem 271:16720-16724
    • (1996) J Biol Chem , vol.271 , pp. 16720-16724
    • Duan, H.J.1    Orth, K.2    Chinnaiyan, A.M.3
  • 42
    • 0344053451 scopus 로고    scopus 로고
    • In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
    • 42. Fernandes-Alnemri T, Armstrong RC, Krebs J et al (1996) In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc Natl Acad Sci USA 93:7464-7469
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7464-7469
    • Fernandes-Alnemri, T.1    Armstrong, R.C.2    Krebs, J.3
  • 43
    • 15844412409 scopus 로고    scopus 로고
    • FLICE, a novel FADD-homologous ICE/ CED-3-like protease, is recruited to the CD95 (Fas/ Apo-1) death-inducing signaling complex
    • 43. Muzio M, Chinnaiyan AM, Kischkel FC et al (1996) FLICE, a novel FADD-homologous ICE/ CED-3-like protease, is recruited to the CD95 (Fas/ Apo-1) death-inducing signaling complex. Cell 85:817-827
    • (1996) Cell , vol.85 , pp. 817-827
    • Muzio, M.1    Chinnaiyan, A.M.2    Kischkel, F.C.3
  • 44
    • 0029832173 scopus 로고    scopus 로고
    • Cleavage of CPP-32 by granzyme B represents a critical role for granzyme b in the induction of target cell DNA fragmentation
    • 44. Darmon AJ, Ley TJ, Nicholson DW, Bleackley RC (1996) Cleavage of CPP-32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation. J Biol Chem 271:21709-21712
    • (1996) J Biol Chem , vol.271 , pp. 21709-21712
    • Darmon, A.J.1    Ley, T.J.2    Nicholson, D.W.3    Bleackley, R.C.4
  • 45
    • 0029808205 scopus 로고    scopus 로고
    • Identification and characterization of Ich-3, a member of the interleukin-1-beta converting enzyme (ICE)/ Ced-3 family and an upstream regulator of ICE
    • 45. Wang S, Miura M, Jung Y et al (1996) Identification and characterization of Ich-3, a member of the interleukin-1-beta converting enzyme (ICE)/ Ced-3 family and an upstream regulator of ICE. J Biol Chem 271:20580-20587
    • (1996) J Biol Chem , vol.271 , pp. 20580-20587
    • Wang, S.1    Miura, M.2    Jung, Y.3
  • 46
    • 0029861379 scopus 로고    scopus 로고
    • The Ced-3/ Interleukin 1 beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32
    • 46. Srinivasula SM, Fernandes-Alnemri T, Zangrilli J et al (1996) The Ced-3/ Interleukin 1 beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32. J Biol Chem 271:27099-27106
    • (1996) J Biol Chem , vol.271 , pp. 27099-27106
    • Srinivasula, S.M.1    Fernandes-Alnemri, T.2    Zangrilli, J.3
  • 47
    • 0017441095 scopus 로고
    • Mechanism of specific tumor cell lysis by alloimmune T lymphocytes: Resolution and characterization of discrete steps in the cellular interaction
    • 47. Martz E (1977) Mechanism of specific tumor cell lysis by alloimmune T lymphocytes: Resolution and characterization of discrete steps in the cellular interaction. Contemp Top Immunobiol 7:301-361
    • (1977) Contemp Top Immunobiol , vol.7 , pp. 301-361
    • Martz, E.1
  • 48
    • 0021183979 scopus 로고
    • Cytolytic activity of purified cytoplasmic granules from cytotoxic rat LGL tumors
    • 48. Henkart PA, Millard PJ, Reynolds CW, Henkart MP (1984) Cytolytic activity of purified cytoplasmic granules from cytotoxic rat LGL tumors. J Exp Med 160:75-93
    • (1984) J Exp Med , vol.160 , pp. 75-93
    • Henkart, P.A.1    Millard, P.J.2    Reynolds, C.W.3    Henkart, M.P.4
  • 49
    • 0021270576 scopus 로고
    • Cytolytic T cell granules. Isolation, biochemical and functional characterization
    • 49. Podack ER, Konigsberg PJ (1984) Cytolytic T cell granules. Isolation, biochemical and functional characterization. J Exp Med 160:695-710
    • (1984) J Exp Med , vol.160 , pp. 695-710
    • Podack, E.R.1    Konigsberg, P.J.2
  • 50
    • 0029976410 scopus 로고    scopus 로고
    • A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection
    • 50. Rodriguez I, Matsuura K, Khatib K, Reed JC, Nagata S, Vassalli P (1996) A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection. J Exp Med 183:1031-1036
    • (1996) J Exp Med , vol.183 , pp. 1031-1036
    • Rodriguez, I.1    Matsuura, K.2    Khatib, K.3    Reed, J.C.4    Nagata, S.5    Vassalli, P.6
  • 51
    • 0029001451 scopus 로고
    • A new flow cytometric method for discrimination of apoptotic cells and detection of their cell cycle apecificity through staining of F-actin and DNA
    • 51. Endresen PC, Prytz PS, Aarbakke J (1995) A new flow cytometric method for discrimination of apoptotic cells and detection of their cell cycle apecificity through staining of F-actin and DNA. Cytometry 20:162-171
    • (1995) Cytometry , vol.20 , pp. 162-171
    • Endresen, P.C.1    Prytz, P.S.2    Aarbakke, J.3
  • 52
    • 0002559045 scopus 로고    scopus 로고
    • The repression of apoptosis by activated abl oncogenes in chronic myelogenous leukaemia
    • 52. Fernandes RS, Gorman AM, McGahon A, Lawlor M, McCann S, Cotter TG (1996) The repression of apoptosis by activated abl oncogenes in chronic myelogenous leukaemia. Leukemia 10 Suppl 2:s17-21
    • (1996) Leukemia , vol.10 , Issue.SUPPL. 2
    • Fernandes, R.S.1    Gorman, A.M.2    McGahon, A.3    Lawlor, M.4    McCann, S.5    Cotter, T.G.6
  • 53
    • 0030065141 scopus 로고    scopus 로고
    • BCR-ABL does not prevent apoptotic death induced by human natural killer or lymphokine-activated killer cells
    • 53. Roger R, Issaad C, PallardyM et al (1996) BCR-ABL does not prevent apoptotic death induced by human natural killer or lymphokine-activated killer cells. Blood 87:1113-1122
    • (1996) Blood , vol.87 , pp. 1113-1122
    • Roger, R.1    Issaad, C.2
  • 54
    • 0028961520 scopus 로고
    • Cytotoxic T cells overcome BCR-ABL-mediated resistance to apoptosis
    • 54. Fuchs EJ, Bedi A, Jones RJ, Hess AD (1995) Cytotoxic T cells overcome BCR-ABL-mediated resistance to apoptosis. Cancer Res 55:463-466
    • (1995) Cancer Res , vol.55 , pp. 463-466
    • Fuchs, E.J.1    Bedi, A.2    Jones, R.J.3    Hess, A.D.4
  • 55
    • 0027979832 scopus 로고
    • BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death
    • 55. McGahon A, Bissonnette R, Schmitt M, Cotter KM, Green DR, Cotter TG (1994) BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death. Blood 83:1179-1187
    • (1994) Blood , vol.83 , pp. 1179-1187
    • McGahon, A.1    Bissonnette, R.2    Schmitt, M.3    Cotter, K.M.4    Green, D.R.5    Cotter, T.G.6
  • 56
    • 0030028582 scopus 로고    scopus 로고
    • Immunoregulatory effects of fas-mediated signalling
    • 56. Lynch DH, Alderson MR, Ramsdell F (1996) Immunoregulatory effects of Fas-mediated signalling. J Cell Biochem 60:39-46
    • (1996) J Cell Biochem , vol.60 , pp. 39-46
    • Lynch, D.H.1    Alderson, M.R.2    Ramsdell, F.3
  • 57
    • 0028919309 scopus 로고
    • A simple assay for examining the effect of transiently expressed genes on programmed cell death
    • 57. Memon SA, Petrak D, Moreno MB, Zacharchuk CM (1995) A simple assay for examining the effect of transiently expressed genes on programmed cell death. J Immunol Methods 180:15-24
    • (1995) J Immunol Methods , vol.180 , pp. 15-24
    • Memon, S.A.1    Petrak, D.2    Moreno, M.B.3    Zacharchuk, C.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.