Distribution of aluminum phthalocyanine disulfonate in an oral squamous cell carcinoma model. In vivo fluorescence imaging compared with ex vivo analytical methods

Photochemistry and Photobiology

Volumn 65, Issue 4, 1997, Pages 685-693

  Witjes, M J H ^a   Mank, A J G ^b   Speelman, O C ^c   Posthumus, R ^b   Nooren, C A A M ^a   Nauta, J M ^a   Roodenburg, J L N ^a   Star, W M ^b  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM PHTHALOCYANINE DISULFONATE; DIAGNOSTIC AGENT; INDOLE DERIVATIVE; ORGANOMETALLIC COMPOUND; PHOTOSENSITIZING AGENT;

ANIMAL; ARTICLE; FLUORESCENCE MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; METABOLISM; MOUTH TUMOR; RAT; SPECTROFLUOROMETRY; SQUAMOUS CELL CARCINOMA; WISTAR RAT;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; INDOLES; MALE; MICROSCOPY, FLUORESCENCE; MOUTH NEOPLASMS; ORGANOMETALLIC COMPOUNDS; PHOTOSENSITIZING AGENTS; RATS; RATS, WISTAR; SPECTROMETRY, FLUORESCENCE;

EID: 0031127341     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Rosenthal, I., E. Ben-Hur, S. Greenberg, A. Concepcion-Lam, D. M. Drew and C. C. Leznoff (1987) The effect of substituents on phthalocyanine photocytotoxicity. Photochem. Photobiol. 46, 959-963.
2. Langlois, R., H. Ali, N. Brasseur, J. R. Wagner and J. E. Van Lier (1986) Biological activities of phthalocyanines - IV. Type II sensitized photooxidation of L-tryptophan and cholesterol by sulphonated metallophthalocyanines. Photochem. Photobiol. 44, 117-125.
3. Wu, S., H. Zhang, G. Cui, D. Xu and H. Xu (1985) A study on the ability of some phthalocyanine compounds for photogenerating singlet oxygen. Acta Chim. Sin. 43, 21-25.
4. Chan, W. S., J. F. Marshall, R. K. Svensen, D. Phillips and I. R. Hart (1987) Photosensitising activity of phthalocyanine dyes screened against tissue culture cells. Photochem. Photobiol. 45, 757-761.
5. Brasseur, N., H. Ali, R. Langlois and J. E. Van Lier (1987) Biological activities of phthalocyanines - VII. Photoinactivation of V-79 Chinese hamster cells by selectively sulfonated gallium phthalocyanines. Photochem. Photobiol. 46, 739-744.
6. Chan, W. S., C. M. L. West, J. V. Moore and I. R. Hart (1991) Photocytotoxic efficacy of sulphonated species of aluminium phthalocyanine against cell monolayers, multicellular spheroids and in vivo tumours. Br. J. Cancer 64, 827-832.
7. Mank, A. G. J., C. Gooijer, H. Lingeman, N. H. Velthorst and U. A. T. Brinkman (1993) Selective and sensitive in vitro detection method for aluminum phthalocyanine photosensitizers, using liquid chromatography and diode-laser induced fluorescence. Anal. Chim. Acta 290, 103-120.
8. Boyle, R. W., B. Paquette and J. E. Van Lier (1992) Biological activities of phthalocyanines XIV. Effect of hydrophobic phthalimidomethyl groups on the in vivo phototoxicity and mechanism of photodynamic action of sulphonated aluminum phthalocyanines. Br. J. Cancer 65, 813-817.
9. Ambroz, M., A. Beeby, A. J. MacRobert, M. S. C. Simpson, R. K. Svensen and D. Phillips (1991) Preparative, analytical and fluorescence spectroscopic studies of sulphonated aluminum phthalocyanine photosensitizers. J. Photochem. Photobiol. B Biol. 9, 87-95.
10. Ali, H., R. Langlois, J. R. Wagner, N. Brasseur, B. Paquette and J. E. Van Lier (1988) Biological activities of phthalocyanines - X. Synthesis and analyses of sulphonated phthalocyanines. Photochem. Photobiol. 47, 713-717.
11. Paquette, B. and J. E. Van Lier (1992) Phthalocyanines and related compounds: structure-activity relationships. In Photodynamic Therapy. Basic Principles and Clinical Applications (Edited by B. Henderson and T. Dougherty), pp. 145-156. Marcel Dekker, New York.
12. Fisker, A. V. (1978) Chemically induced experimental oral carcinogenesis. Establishment of an experimental model based on application of the carcinogen 4-nitroquinoline n-oxide on the palatal mucosa of rats. Ph.D. Thesis, Royal Dental College, Copenhagen.
13. Prime, S. S., D. Malamos, T. J. Rosser and C. M. Scully (1986) Oral epithelial atypia and acantholytic dyskeratosis in rats painted with 4-nitroquinoline N-oxide. J. Oral Pathol. 15, 280-283.
14. Nauta, J. M., J. L. N. Roodenburg, P. G. J. Nikkels, M. J. H. Witjes and A. Vermey (1995) Comparison of epithelial dysplasia. The 4NQO rat palatal model versus human oral mucosa. Int. J. Oral Maxillofac. Surg. 24, 53-58.
15. Van Leengoed, H. L. L. M., N. van der Veen, A. A. C. Versteeg, R. Ouellet, J. E. Van Lier and W. M. Star (1993) In vivo fluorescence kinetics of phthalocyanines in a skin-fold chamber model: role of central metal ion and degree of sulfonation. Photochem. Photobiol. 58, 233-237.
16. Witjes, M. J. H., O. C. Speelman, P. G. J. Nikkels, C. A. A. M. Nooren, J. M. Nauta, B. van der Holt, H. L. L. M. Van Leengoed, W. M. Star and J. L. N. Roodenburg (1996) In-vivo fluorescence kinetics and localisation of aluminum phthalocyanine disulfonate in an autologous tumour model. Br. J. Cancer 73, 573-580.
17. Spike, R. C., A. P. Payne, G. G. Thompson and M. R. Moore (1990) High-performance liquid chromatographic analyses of porphyrins in hamster Harderian glands. Biochim. Biophys. Acta 1034, 1-3.
18. Kondo, S. (1981) Molecular biology of 4-nitroquinoline 1-oxide in the prokaryotic system. In The Nitroquinolines (Edited by T. Sugimura), pp. 47-64. Raven Press, New York.
19. Tralau, C. J., H. Barr, D. R. Sandeman, T. Barton, M. R. Lewin and S. G. Bown (1987) Aluminum sulfonated phthalocyanine distribution in rodent tumors of the colon, brain and pancreas. Photochem. Photobiol. 46, 777-781.
20. Loh, C. S., J. Bedwell, A. J. MacRobert, N. Krasner, D. Phillips and S. G. Bown (1992) Photodynamic therapy of the normal rat stomach: a comparative study between disulphonated aluminum phthalocyanine and 5-aminoleavulinic acid. Br. J. Cancer 66, 452-462.
21. Chatlani, P. T., J. Bedwell, A. J. MacRobert, H. Barr, P. B. Boulos, N. Krasner, D. Phillips and S. G. Bown (1991) Comparison of distribution and photodynamic effects of di-and tetra sulphonated aluminum phthalocyanines in normal rat colon. Photochem. Photobiol. 53, 745-751.
22. Frisoli, J. K., E. G. Tudor, T. J. Flotte, T. Hasan, T. F. Deutsch and K. T. Schomacker (1993) Pharmacokinetics of a fluorescent drug using laser-induced fluorescence. Cancer Res. 53, 5954-5961.
23. Poon, W. S., K. T. Schomacher, T. F. Deutsch and R. L. Martuza (1992) Laser-induced fluorescence: experimental intraoperative delineation of tumor resection margins. J. Neurosurg. 76, 697-686.
24. Peng, Q., J. Moan, J. M. Nesland and C. Rimington (1990) Aluminum phthalocyanines with asymmetrical lower sulphonation and with symmetrical higher sulphonation: a comparison of localizing and photosensitizing mechanism in human tumor LOX xenografts. Int. J. Cancer 46, 719-726.
25. Peng Q., J. Moan, G. Farrants, H. E. Danielsen and C. Rimington (1991) Localisation of potent photosensitizers in human tumor LOX by means of laser scanning microscopy. Cancer Lett. 58, 17-27.
26. Chen, J. Y., W. Chen, H. X. Cai and R. C. Dong (1993) Studies on pharmacokinetics of sulfonated aluminum phthalocyanine in a transplantable mouse tumor by in vivo fluorescence. J. Photochem. Photobiol. B 18, 233-237.
27. Chan, W. S., J. F. Marshall, R. Svensen, J. Bedwell and I. R. Hart (1990) Effect of sulfonation on the cell and tissue distri-bution of the photosensitizer aluminum phthalocyanine. Cancer Res. 50, 4533-4538.
28. Peng, Q. and J. Moan (1995) Correlation of distribution of sulphonated aluminum phthalocyanines with their photodynamic effect in tumour and skin of mice bearing CaD2 mammary carcinoma. Br. J. Cancer 72, 565-574.