Acute renal failure and proximal tubule lesions after trichosanthin injection in rats

Experimental and Molecular Pathology

Volumn 64, Issue 2, 1997, Pages 78-89

  Tang, Nelson L S ^a   Chan, Wah lun ^a   Ke, Yi bao ^a   Mak, Michael K F ^a   Lai, Fernand M ^a   Tam, Siu cheung ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

TRICHOSANTHIN;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CREATININE CLEARANCE; DOSE RESPONSE; DRUG EFFECT; KIDNEY PROXIMAL TUBULE; NONHUMAN; PATHOGENESIS; RAT; TOXICITY TESTING;

ANIMALIA;

EID: 0031126686     PISSN: 00144800     EISSN: None     Source Type: Journal    
DOI: 10.1006/exmp.1997.2210     Document Type: Article

References (33)

1. Barbieri L., Battelli M. G., Stirpe F. Blood clearance and organ distribution and tissue concentration of native, homopolymerized and IgG-conjugated ribosome-inactivating proteins. Xenobiotica. 20:1990;1331-1341.
2. Battelli G. M., Barbieri L., Stirpe F. Toxicity of and histological lesions caused by, ribosome-inactivating proteins, their IgG-conjugates, and their homopolymers. APMIS. 98:1990;585-593.
3. Battelli M. G., Buonamici L., Polito L., Bolognesi A., Stirpe F. Hepatotoxicity of ricin, saporin or a saporin immunotoxin: Xanthine oxidase activity in rat liver and blood serum. Virchows Arch. 427:1996;529-535.
4. Beeri R., Symon Z., Brezis M. Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys. Kidney Int. 47:1995;1806-1810.
5. Blakey D. C., Skilleter D. N., Price R. J. Comparison of the pharmacokinetics and hepatotoxic effects of saporin and ricin A-chain immunotoxins on murine liver parenchymal cells. Cancer Res. 48:1988;7072-7078.
6. Brezis M., Rosen S. Hypoxia of the renal medulla - Its implications for disease. N. Engl. J. Med. 332:1995;647-655.
7. Egarter C., Husslein P., Yeung H. W. Trichosanthin injection in tubal pregnancy. Gynecol. Obstet. Invest. 31:1991;119-120.
8. Gold R., Schmied M., Giegerich G. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Lab. Invest. 71:1994;219-225.
9. Hamada T., Sasaguri T., Tanimoto A. Apoptosis of human kidney 293 cells is promoted by polymerized cadmium-metallothionein. Biochem. Biophys. Res. Commun. 219:1996;829-834.
10. Ito H., Kasagi N., Shomori K. Apoptosis in the human allografted kidney. analysis by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling. Transplantation. 60:1995;794-798.
11. Kahn J. O., Gorelick K. J., Gatti G. Safety, activity, and pharmacokinetics of GLQ223 in patients with AIDS and AIDS-related complex. Antimicrob. Agents Chemother. 38:1994;260-267.
12. Ko W. H., Wong C. C., Yeung H. W., Yung M. H., Shaw P. C., Tam S. C. Increasing the plasma half life of trichosanthin by coupling to dextran. Biochem. Pharmacol. 42:1991;1721-1728.
13. Ko W. H., Tam S. C. Renal reabsorption of trichosanthin and the effect on GFR. Renal Failure. 16:1994;359-366.
14. Lau I. F., Saksena S. K., Chang M. C. Further studies on the Trichosanthin-induced termination of pregnancy. Contraception. 21:1980;77-86.
15. Lu P. X., Jin Y. C. Trichosanthin in the treatment of hydatidiform mole. Clinical analysis of 52 cases. Chin. Med. J. 103:1990;183-185.
16. Maack T. Renal handling of proteins and polypeptides. Handbook of Physiology: Renal Physiology. 1992;Oxford Univ. Press, London. p. 2039-2082.
17. Maraganore J. M., Joseph M., Bailey M. C. Purification and characterization of trichosanthin: Homology to the ricin A chain and implications as to mechanism of abortifacient activity. J. Biol. Chem. 262:1987;11628-11633.
18. Mayer R. A., Sergios P. A., Coonan K., O'Brien L. Trichosanthin treatment of HIV-induced immune dysregulation. Eur. J. Clin. Invest. 22:1992;113-122.
19. Nouwen E. J., Verstrepen W. A., Buyssens N. Hyperplasia, hypertrophy and phenotypic alternations in the distal nephron after acute proximal tubular injury in the rat. Lab. Invest. 70:1994;479-493.
20. Ramsden C. S., Drayson M. T., Bell E. B. The toxicity, distribution and excretion of ricin holotoxin in rats. Toxicology. 55:1989;161-171.
21. Savill J. Apoptosis and renal injury. Curr. Opin. Nephrol. Hypertension. 4:1995;263-269.
22. Schumer M., Colombel M. C., Sawczuk I. S. Morphologic, biochemical and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischemia. Am. J. Pathol. 140:1992;831-838.
23. Shaw P. C., Chan W. L., Yeung H. W., Ng T. B. Minireview: Trichosanthin - A protein with multiple pharmacological properties. Life Sci. 55:1994;253-262.
24. Shimizu A., Yamaanaka N. Apoptosis and cell desquamation in repair process of ischemic tubular necrosis. Virchows Arch. B. 64:1993;171-180.
25. Stirpe F., Derenzini M., Barbieri L. Hepatotoxicity of immunotoxins made from saporin, a ribosome-inactiviating protein from Saponaria officinalis. Virchows Arch. B. 53:1987;259-271.
26. Tanimoto A., Hamada T., Koide O. Cell death and regeneration of renal proximal tubular cells in rats with subchronic cadmium intoxication. Toxicol. Pathol. 21:1993;341-352.
27. Ueda N., Walker P. D., Hsu S. M., Shah S. V. Activation of a 15 kDa endonuclease in hypoxia/reoxygenation injury without morphologic features of apoptosis. Proc. Natl. Acad. Sci. USA. 92:1995;7202-7206.
28. Wang Q. C., Ying W. B., Xie H. Trichosanthin-monoclonal antibody conjugate specifically cytotoxic to human hepatoma cells in vitro. Cancer Res. 51:1991;3353-3355.
29. Yeung H. W., Wong D. M., Ng T. B., Li W. W. Purification of three isolectins from root tubers of Trichosanthes kirilowii (Tan Hua Fen). Int. J. Pept. Prot. Res. 27:1986;325-333.
30. Yeung H. W., Li W. W., Feng Z., Barbieri L., Stripe F. Trichosanthin, α-momorcharin and β-momorcharin: identity of abortifacient and ribosome-inactivating proteins. Int. J. Pept. Prot. Res. 31:1988;265-268.
31. Zager R. A., Fuerstenberg S. M., Baehr P. H. An evaluation of antioxidant effects on recovery from postischemic acute renal failure. J. Am. Soc. Nephrol. 4:1994;1588-1597.
32. Zhang X., Wang J. Homology of trichosanthin and ricin A-chain. Nature (London). 321:1986;477-478.
33. Zheng Y. T., Zhang W. F., Ben K. L. In vitro immunotoxicity and cytotoxicity of trichosanthin against human normal immunocytes and leukemia-lymphoma cells. Immunopharmacol. Immunotoxicol. 17:1995;69-79.