Prolactin Administration to Seasonally Anestrous Mares: Reproductive, Metabolic, and Hair-Shedding Responses

Journal of Animal Science

Volumn 75, Issue 4, 1997, Pages 1092-1099

  Thompson Jr , Donald L ^b   Hoffman, Rick ^a,b   DePew, Christopher L ^b  

^a MONSANTO COMPANY   (United States)

^b LOUISIANA STATE UNIVERSITY AGRICULTURAL CENTER   (United States)

Author keywords

Anestrus; Mares; Metabolism; Ovulation; Prolactin; Seasonality

Indexed keywords

EQUIDAE; EQUUS CABALLUS; SUIDAE;

ANTIBODY; FATTY ACID; FOLLITROPIN; GONADOTROPIN; HYDROCORTISONE; LUTEINIZING HORMONE; PROLACTIN; RADIOACTIVE IODINE; SOMATOMEDIN C;

ANESTRUS; ANIMAL; ARTICLE; BLOOD; DRUG EFFECT; ECHOGRAPHY; ESTRUS; FEMALE; FERTILITY; GLUCOSE BLOOD LEVEL; HAIR; HORSE; IMMUNOLOGY; METABOLISM; OVARY; OVARY FOLLICLE; OVULATION; PHYSIOLOGY; REPRODUCTION; SEASON;

ANESTRUS; ANIMALS; ANTIBODIES; BLOOD GLUCOSE; ESTRUS; FATTY ACIDS, NONESTERIFIED; FEMALE; FERTILITY; FOLLICLE STIMULATING HORMONE; GONADOTROPINS; HAIR; HORSES; HYDROCORTISONE; INSULIN-LIKE GROWTH FACTOR I; IODINE RADIOISOTOPES; LUTEINIZING HORMONE; OVARIAN FOLLICLE; OVARY; OVULATION; PROLACTIN; REPRODUCTION; SEASONS;

EID: 0031114423     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/1997.7541092x     Document Type: Article

References (47)

1. Advis, P. J., S. Smith-White, and S. R. Ojeda. 1981. Delayed puberty induced by chronic suppression of prolactin release in the female rat. Endocrinology 109:1321.
2. Bartke, A., B. D. Goldman, F. J. Bex, R. P. Kelch, M. S. Smith, S. Dalterio, and P. C. Doherty. 1980. Effects of prolactin on testicular regression and recrudescence in the golden hamster. Endocrinology 106:167.
3. Cincotta, A. H., and A. H. Meier. 1985a. Prolactin permits the expression of a circadian variation in insulin receptor profile in hepatocytes of the golden hamster Mesocricetus auratus. J. Endocrinol. 106:177.
4. Cincotta, A. H., and A. H. Meier. 1985b. Prolactin permits the expression of a circadian variation in lipogenic responsiveness to insulin in hepatocytes of the golden hamster Mesocricetus auratus. J. Endocrinol. 106:173.
5. Cincotta, A. H., and A. H. Meier. 1987. Reduction of body fat stores by inhibition of prolactin secretion. Experientia (Basel) 43:416.
6. Colborn, D. R., D. L. Thompson, Jr., M. S. Rahmanian, and T. L. Roth. 1991a. Plasma concentrations of cortisol, prolactin, luteinizing hormone, and follicle-stimulating hormone in stallions after physical exercise and injection of secretagogue before and after sulpiride treatment in winter. J. Anim. Sci. 69:3724.
7. Colborn, D. R., D. L. Thompson, Jr., T. L. Roth, J. S. Capehart, and K. L. White. 1991b. Responses of cortisol and prolactin to sexual excitement and stress in stallions and geldings. J. Anim. Sci. 69:2556.
8. DePew, C. L., D. L. Thompson, Jr., J. M. Fernandez, L. L. Southern, L. S. Sticker, and T. L. Ward. 1994a. Plasma concentrations of prolactin, glucose, insulin, urea nitrogen, and total amino acids in stallions after ingestion of feed or gastric administration of feed components. J. Anim. Sci. 72:2345.
9. DePew, C. L., D. L. Thompson, Jr., J. M. Fernandez, L. S. Sticker, and D. W. Burleigh. 1994b. Changes in concentrations of hormones, metabolites, and amino acids in plasma of adult horses relative to overnight feed deprivation followed by a pellet-hay meal fed at noon. J. Anim. Sci. 72:1530.
10. Duncan, M. J., and B. D. Goldman. 1984. Hormonal regulation of the annual pelage color cycle in the Djungarian hamster, Phodopus sungorus. II. Role of prolactin. J. Exp. Zool. 230:97.
11. Ensor, D. M. 1978. Comparative Endocrinology of Prolactin. John Wiley & Sons, New York.
12. Fluckiger, E., E. dal Pozo, and K. von Werder. 1982. Prolactin. Physiology, Pharmacology, and Clinical Findings. Springer-Verlag, New York.
13. Foster, J. P., M. J. Evans, and C.H.G. Irvine. 1979. Differential release of LH and FSH in cyclic mares in response to synthetic GnRH. J. Reprod. Fertil. 56:567.
14. Garcia, M. C., and O. J. Ginther. 1978. Regulation of plasma LH by estradiol and progesterone in ovariectomized mares. Biol. Reprod. 19:447.
15. Gill, J. L., and H. D. Hafs. 1971. Analysis of repeated measurements of animals. J. Anim. Sci. 33:331.
16. Ginther, O. J. 1992. Reproductive Biology of the Mare. Basic and Applied Aspects. Equiservices, Cross Plains, WI.
17. Hart, P. J., E. L. Squires, K. J. Imel, and T. M. Nett. 1984. Seasonal variation in hypothalamic content of gonadotropin-releasing hormone (GnRH), pituitary receptors for GnRH, and pituitary content of luteinizing hormone and follicle stimulating hormone in the mare. Biol. Reprod. 30:1055.
18. Jaffe, R. B. 1981. Prolactin. Elsevier, New York.
19. Johnson, A. L. 1986. Serum concentrations of prolactin, thyroxine and triiodothyronine relative to season and the estrous cycle in the mare. J. Anim. Sci. 62:1012.
20. Johnson, A. L. 1987. Seasonal and photoperiod-induced changes in serum prolactin and pituitary responsiveness to thyrotropin-releasing hormone in the mare. Proc. Soc. Exp. Biol. Med. 184: 118.
21. Jones, P.B.C., and A.J.W. Hsueh. 1981. Direct effects of gonadotropin-releasing hormone and its antagonist on ovarian functions stimulated by follicle-stimulating hormone, prolactin, and luteinizing hormone. Biol. Reprod. 24:747.
22. McLaughlin, C. L., J. C. Byatt, N. R. Staten, W. J. Salsgiver, J. J. Veenhuizen, J. G. Kostelc, M. F. McGrath, T. R. Kasser, R. J. Collier and C. A. Baile. 1992. Effects of recombinant prolactin on growth, carcass composition and clinical chemistries of mature female rats and finishing hogs. J. Anim. Sci. 70(Suppl. 1): 203 (Abstr.).
23. Monroe, J. L., D. L. Cross, L. W. Hudson, D. M. Hendricks, S. W. Kennedy, and W. C. Bridges, Jr. 1988. Effect of selenium and endophyte-contaminated fescue on performance and reproduction in mares. J. Equine Vet. Sci. 8:148.
24. Nequin, L. G., S. S. King, A. L. Johnson, G. M. Gow, and G. M. Ferreira-Dias. 1993. Prolactin may play a role in stimulating the equine ovary during the spring reproductive transition. J. Equine Vet. Sci. 13:631.
25. Purvis, K., and V. Hansson. 1978. Hormonal regulation of Leydig cell function. Mol. Cell. Endocrinol. 12:123.
26. Rabb, M. H., D. L. Thompson, Jr., B. E. Barry, D. R. Colborn, F. Garza, Jr., and K. E. Hehnke. 1989. Effects of sexual stimulation with and without ejaculation, on serum concentrations of LH, FSH, testosterone, cortisol and prolactin in stallions. J. Anim. Sci. 67:2724.
27. SAS. 1988. SAS/STAT® User's Guide (Release 6.03). SAS Inst. Inc., Cary, NC.
28. Sharp, D. C., W. R. Grubaugh, J. Weitenauer, S. D. Davis, and C. J. Wilcox. 1991. Effects of steroid administration on pituitary luteinizing hormone and follicle-stimulating hormone in ovariectomized pony mares in the early spring: Pituitary responsiveness to gonadotropin-releasing hormone and pituitary gonadotropin content. Biol. Reprod. 44:983.
29. Silvia, P. J., E. L. Squires, and T. M. Nett. 1986. Changes in the hypothalamic-hypophyseal axis of mares associated with seasonal reproductive recrudescence. Biol. Reprod. 35:897.
30. Silvia, P. J., E. L. Squires, and T. M. Nett. 1987. Pituitary responsiveness of mares challenged with GnRH at various stages of the transition into the breeding season. J. Anim. Sci. 64:790.
31. Smale, L., T. M. Lee, R. J. Nelson, and I. Zucker. 1990. Prolactin counteracts effects of short day lengths on pelage growth in the meadow vole, Microtus pennsylvanicus. J. Exp. Zool. 253:186.
32. Smith, A. J., M. Mondain-Monval, P. Simon, K. A. Berg, O.P.F. Clausen, P. O. Hofmo, and R. Scholler. 1987. Preliminary studies of the effects of bromocriptine on testicular regression and the spring molt in a seasonal breeder, the male blue fox, Alopex lagopus. J. Reprod. Fertil. 81:517.
33. Steel, R.G.D., and J. H. Torrie. 1980. Principles and Procedures of Statistics: A Biometrieal Approach (2nd Ed.). McGraw-Hill Publishing Co., New York.
34. Sticker, L. S., D. L. Thompson, Jr., J. M. Fernandez, L. D. Bunting, and C. L. DePew. 1995. Dietary protein and(or) energy restriction in mares: Plasma growth hormone, IGF-I, prolactin, cortisol, and thyroid hormone responses to feeding, glucose, and epinephrine. J. Anim. Sci. 73:1424.
35. Thompson, D. L., Jr., C. L. DePew, A. Ortiz, L. S. Sticker, and M. S. Rahmanian. 1994. Growth hormone and prolactin concentrations in plasma of horses: Sex differences and the effects of acute exercise and administration of growth hormone-releasing hormone. J. Anim. Sci. 72:2911.
36. Thompson, D. L., Jr., F. Garza, Jr., K. B. Ashley, and J. J. Wiest. 1986a. Androgen and progesterone effects on follicle-stimulating hormone and luteinizing hormone secretion in anestrous mares. Biol. Reprod. 34:51.
37. Thompson, D. L., Jr., F. Garza, Jr., P. S. Mitchell, and R. L. St. George. 1988. Effects of short-term stress, xylazine tranquilization and anesthetization with xylazine plus ketamine on plasma concentrations of cortisol, luteinizing hormone, follicle stimulating hormone and prolactin in ovariectomized pony mares. Theriogenology 30:937.
38. Thompson, D. L., Jr., R. A. Godke, and E. L. Squires. 1983a. Testosterone effects on mares during synchronization with altrenogest: FSH, LH, estrous duration and pregnancy rate. J. Anim. Sci. 56:678.
39. Thompson, D. L., Jr., and L. Johnson. 1987. Effects of age, season and active immunization against estrogen on serum prolactin concentrations in stallions. Domest. Anim. Endocrinol. 4:17.
40. Thompson, D. L., Jr., L. Johnson, R. L. St. George, and F. Garza, Jr. 1986b. Concentrations of prolactin, luteinizing hormone and follicle stimulating hormone in pituitary and serum of horses: Effect of sex, season and reproductive state. J. Anim. Sci. 63: 854.
41. Thompson, D. L., Jr., L. Johnson, and J. J. Wiest. 1987. Effects of month and age on prolactin concentrations in stallion serum. J. Reprod. Fertil. Suppl. 35:67.
42. Thompson, D. L. Jr., and T. M. Nett. 1984. Thyroid stimulating hormone and prolactin secretion after thyrotropin releasing hormone administration to mares: Dose response during anestrus in winter and during estrus in summer. Domest. Anim. Endocrinol. 1:263.
43. Thompson, D. L., Jr., S. I. Reville-Moroz, D. J. Derrick, and M. P. Walker. 1983b. Effects of testosterone, dihydrotestosterone and estradiol on gonadotropin release after gonadotropin releasing hormone administration in cyclic mares. Biol. Reprod. 29:970.
44. Thompson, D. L., Jr., S. I. Reville, M. P. Walker, D. J. Derrick, and H. Papkoff. 1983c. Testosterone administration to mares during estrus: Duration of estrus and diestrus and concentrations of LH and FSH in plasma. J. Anim. Sci. 56:911.
45. Thompson, D. L., Jr., J. J. Wiest, and T. M. Nett. 1986c. Measurement of equine prolactin with an equine-canine radioimmunoassay: Seasonal effects on the prolactin response to thyrotropin releasing hormone. Domest. Anim. Endocrinol. 3: 247.
46. Van Straalen, R.J.C., and G. H. Zeilmaker. 1982. Observations on the effects of prolactin on luteinizing hormone receptors and steroidogenesis in corpus luteum and testis of the hypophysectomized rat. Acta Endocrinol. 99:437.
47. Worthy, K., K. Colquhoun, R. Escreet, M. Dunlop, J. P. Renton, and T. A. Douglas. 1987. Plasma prolactin concentrations in non-pregnant mares at different times of the year and in relation to events in the cycle. J. Reprod. Fertil. Suppl. 35:269.