An Inherited Platelet Function Defect in a Simmental Crossbred Herd

Canadian Journal of Veterinary Research

Volumn 61, Issue 2, 1997, Pages 128-133

  Gentry, Patricia A ^a   Cheryk, Lynn A ^a   Shanks, Roger D ^b   Healey, Richard ^c  

^a UNIVERSITY OF GUELPH   (Canada)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c Paris Veterinary Clinic   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; BLOOD CLOTTING FACTOR 11; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLEEDING; BLOOD; BLOOD CLOTTING; BLOOD CLOTTING DISORDER; BLOOD CLOTTING PARAMETERS; CATTLE; CATTLE DISEASE; DRUG EFFECT; FEMALE; GENETICS; HETEROZYGOTE; MALE; PATHOPHYSIOLOGY; PHYSIOLOGY; THROMBOCYTE; THROMBOCYTE AGGREGATION;

ADENOSINE DIPHOSPHATE; ANIMALS; BLOOD COAGULATION; BLOOD COAGULATION DISORDERS; BLOOD PLATELETS; CATTLE; CATTLE DISEASES; FACTOR XI; FEMALE; HEMORRHAGE; HETEROZYGOTE; MALE; PLATELET ACTIVATING FACTOR; PLATELET AGGREGATION; PLATELET FUNCTION TESTS;

EID: 0031114016     PISSN: 08309000     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. KOCIBA GJ. Partial characterization of a hemostatic defect in Simmental Cattle. Vet Clin Pathol 1980; 9: 46-47.
2. SEARCY GP, PETRIE L. Clinical and laboratory findings of a bleeding disorder in eight Simmental cattle. Can Vet J 1990; 31: 101-103.
3. STEFICEK BA, THOMAS JS, BAKER JC, BELL TG. Hemorrhagic diathesis associated with a hereditary platelet disorder in Simmental cattle. J Vet Diagn Invest 1993; 5: 202-207.
4. SULLIVAN PS, GRUBBS ST, OLCHOWY TWJ, ANDREWS FM, WHITE JG, CATALFAMO JL, DODD PA, McDONALD TP. Bleeding diathesis associated with variant von Willebrand factor in a Simmental calf. J Am Vet Med Assoc 1994; 205: 1763-1766.
5. NAVARRE CB, KASARI TR, GREEN RA. Platelet function defect in a 5-day-old Simmental calf. J Vet Intern Med 1995; 9: 283-285.
6. GENTRY PA. The mammalian blood platelet. Its role in haemostasis, inflammation and tissue repair. J Comp Pathol 1992; 107: 243-270.
7. MEYERS KM. Pathobiology of animal platelets. Adv Vet Sci Comp Med 1985; 30: 131-165.
8. WHITE JG. The secretory pathway of bovine platelets. Blood 1987; 69: 878-885.
9. GROUSE LH, RAO GH, WEISS DJ, PERMAN V, WHITE GJ. Surface-activated bovine platelets do not spread, they unfold. Am J Pathol 1990; 136: 399-408.
10. SEARCY GP, SHERIDAN D, DOBSON KA. Preliminary studies of a platelet function disorder in Simmental cattle. Can J Vet Res 1990; 54: 394-396.
11. STEFICEK BA, THOMAS JS, McCONNELL MF, BELL TG. A primary platelet disorder of consanguineous Simmental cattle. Thromb Res 1993; 72: 145-153.
12. SEARCY GP, FROJMOVIC MM, McNICOL A, ROBERTSON C, WONG T, GERRARD JM. Platelets from bleeding Simmental cattle mobilize calcium, phosphorylate myosin light chain and bind normal numbers of fibrinogen molecules but have abnormal cytoskeletal assembly and aggregation in response to ADP. Thromb Haemost 1994; 71: 240-246.
13. BONDY GS, GENTRY PA. Characterization of the normal bovine platelet aggregation response. Comp Biochem Physiol 1989; 92C: 67-72.
14. GENTRY PA, ROSS ML. Failure of routine coagulation screening tests to detect heterozygous state of bovine factor XI deficiency. Vet Clin Pathol 1986; 15: 12-16.
15. YAMADA M, GENTRY PA. The hemostatic profile of equine ovarian follicular fluid. Thromb Res 1995; 77: 45-54.
16. GENTRY PA, DEJONG CG, BASRUR PK. Stability of bovine platelets stored at ambient temperature. Comp Haematol Int 1992; 2: 213-219.
17. GENTRY PA, ROSS ML, HAYATGHEYBI H. Competency of blood coagulation in the newborn calf. Res Vet Sci 1994; 57: 336-342.
18. GENTRY PA, ROSS ML. Coagulation Factor XI deficiency in Holstein cattle: Expression and distribution of Factor XI activity. Can J Vet Res 1994, 58: 242-247.
19. BROZE GJ. The role of tissue factor pathway inhibitor in a revised coagulation cascade. Semin Hematol 1992; 29: 159-169.