Alveolar Macrophages Produce the Env Protein of a Human Endogenous Retrovirus, HERV-E 4-1, in a Subgroup of Interstitial Lung Diseases

American Journal of Respiratory Cell and Molecular Biology

Volumn 16, Issue 4, 1997, Pages 429-437

  Tamura, Naoaki ^a   Iwase, Akihiko ^b   Suzuki, Koji ^b   Maruyama, Naoki ^b   Kira, Shiro ^b  

^a JUNTENDO UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN ENDOGENOUS RETROVIRUS; UNIDENTIFIED RETROVIRUS;

ANTIBODY; DNA; MESSENGER RNA; VIRUS ENVELOPE PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BIOSYNTHESIS; BLOOD; CYTOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HUMAN; IMMUNOLOGY; INTERSTITIAL LUNG DISEASE; LEUKOCYTE; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE REPEAT; PATHOLOGY; POINT MUTATION; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RETROVIRUS; SINGLE STRAND CONFORMATION POLYMORPHISM;

AMINO ACID SEQUENCE; ANTIBODIES; BRONCHOALVEOLAR LAVAGE FLUID; DNA; FLUORESCENT ANTIBODY TECHNIQUE; GENE PRODUCTS, ENV; HUMANS; LEUKOCYTES; LUNG DISEASES, INTERSTITIAL; MACROPHAGES, ALVEOLAR; MOLECULAR SEQUENCE DATA; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; REPETITIVE SEQUENCES, NUCLEIC ACID; RETROVIRIDAE; RNA, MESSENGER;

EID: 0031112340     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.16.4.9115754     Document Type: Article

References (46)

1. Pantaleo, G., C. Graziosi, and A. S. Fauci. 1993. The immunopathogenesis of human immunodeficiency virus infection. N. Engl. J. Med. 328:327-335.
2. Höllsberg, P., and D. A. Hafler. 1993. Pathogenesis of diseases induced by human lymphotropic virus type I infection. N. Engl. J. Med. 328:1173-1182.
3. Leib-Mösch, C., R. Brack-Werner, T. Werner, M. Bachmann, O. Faff, V. Erfle, and R. Hehlmann. 1990. Endogenous retroviral elements in human DNA. Cancer Res. 50:5636s-5642s.
4. Krieg, A. M., M. F. Gourley, and A. Perl. 1992. Endogenous retroviruses: potential etiologic agents in autoimmunity. FASEB J. 6:2537-2544.
5. Martin, M. A., T. Bryan, S. Rasheed, and A. S. Khan. 1981. Identification and cloning of endogenous retroviral sequences present in human DNA. Proc. Natl. Acad. Sci. USA 78:4892-4896.
6. Abraham, G. N., and A. S. Khan. 1990. Human endogenous retroviruses and immune disease. Clin. Immunol. Immunopathol. 56:1-8.
7. Repaske, R., P. E. Steele, R. R. O'Neill, A. B. Rabson, and M. A. Martin. 1985. Nucleotide sequence of a full-length human endogenous retroviral segment. J. Virol. 54:764-772.
8. Wilkinson, D. A., D. L. Mager, and J. C. Leong. 1994. Endogenous human retroviruses. In The Retroviridae, Vol. 3. J. A. Levy, editor. Plenum Press, New York. 465-535.
9. Kalter, S. S., R. J. Helmke, R. L. Heberling, M. Panigel, A. K. Fowler, J. E. Strickland, and A. Hellman. 1973. C-type particles in normal human placentas. J. Natl. Cancer Inst. 50:1081-1084.
10. Kitamura, M., N. Maruyama, T. Shirasawa, R. Nagasawa, K. Watanabe, M. Tateno, and T. Yoshiki. 1994. Expression of an endogenous retroviral gene product in human placenta. Int. J. Cancer 58:836-840.
11. Rabson, A. B., Y. Hamagishi, P. E. Steele, M. Tykocinski, and M. A. Martin. 1985. Characterization of human endogenous retroviral envelope RNA transcripts. J. Virol. 56:176-182.
12. Takeuchi, K., K. Katsumata, H. Ikeda, M. Minami, A. Wakisaka, and T. Yoshiki. 1995. Expression of endogenous retroviruses. ERV3 and λ 4-1, in synovial tissues from patients with rheumatoid arthritis. Clin. Exp. Immunol. 99:338-344.
13. Yoshiki, T., R. C. Mellors, M. Strand, and J. T. August. 1974. The viral envelope glycoprotein of murine leukemia virus and pathogenesis of immune complex glomerulonephritis of New Zealand mice. J. Exp. Med. 140:1011-1027.
14. Crystal, R. G., P. B. Bitterman, S. I. Rennard, A. J. Hance, and B. A. Keogh. 1984. Interstitial lung diseases of unknown cause: disorders characterized by chronic inflammation of the lower respiratory tract. N. Engl. J. Med. 310:154-166, 235-244.
15. Kawanami, O., V. J. Ferrans, J. D. Fulmer, and R. G. Crystal. 1979. Nuclear inclusions in alveolar epithelium of patients with fibrotic lung disorders. Am. J. Pathol. 94:301-322.
16. Thomas, P. D., and G. W. Hunninghake. 1987. Current concepts of the pathogenesis of sarcoidosis. Am. Rev. Respir. Dis. 135:747-760.
17. Saltini, C., and R. G. Crystal. 1985. Pulmonary sarcoidosis: pathogenesis, staging and therapy. Int. Arch. Allergy Appl. Immun. 76(Suppl.):92-100.
18. Yamada, M., N. Tamura, T. Shirai, and S. Kira. 1986. Flow cytometric analysis of lymphocyte subsets in the bronchoalveolar lavage fluid and peripheral blood of healthy volunteers. Scand. J. Immunol. 24:559-565.
19. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
20. The BAL Cooperative Group Steering Committee. 1990. Bronchoalveolar lavage constituents in healthy individuals, idiopathic pulmonary fibrosis, and selected comparison groups. Am. Rev. Respir. Dis. 141:S169-S202.
21. Tamura, N., K. J. Holroyd, T. Banks, M. Kirby, H. Okayama, and R. G. Crystal. 1990. Diversity in junctional sequences associated with the common human V λ9 and V δ 2 gene segments in normal blood and lung compared with the limited diversity in a granulomatous disease. J. Exp. Med. 172:169-181.
22. Saiki, R. K., D. H. Gelfand, S. Stoffel, S. J. Sharf, R. Higuchi, G. T. Horn, K. B. Mullis, and H. A. Erlich. 1988. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239:487-491.
23. Orita, M., Y. Suzuki, T. Sekiya, and K. Hayashi. 1989. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics 5:874-879.
24. Ainsworth, P. J., L. C. Surh, and M. B. Coulter-Mackie. 1991. Diagnostic single strand conformational polymorphism (SSCP): a simplified non-radioisotopic method as applied to a Tay-Sachs B1 variant. Nucl. Acids Res. 19:405-406.
25. Sammons, D. W., L. D. Adams, and E. E. Nishizawa. 1981. Ultrasensitive silver-based color attaining of polypeptides in polyacrylamide gels. Electrophoresis 2:135-141.
26. Scheeren, R. A., R. A. J. Oostendorp, S. Van der Baan, R. M. J. Keehnen, R. J. Scheper, and C. J. L. M. Meijer. 1992. Distribution of retroviral p15E-related proteins in neoplastic and non-neoplastic human tissues, and their role in the regulation of the immune response. Clin. Exp. Immunol. 89:94-99.
27. Krieg, A. M., and A. D. Steinberg. 1990. Retroviruses and autoimmunity. J. Autoimmun. 3:137-166.
28. Medstrand, P., M. Lindeskog, and J. Blomberg. 1992. Expression of human endogenous retroviral sequences in peripheral blood mononuclear cells of healthy individuals. J. Gen. Virol. 73:2463-2466.
29. Hunninghake, G. W., J. E. Gadek, O. Kawanami, V. J. Ferrans, and R. G. Crystal. 1979. Inflammatory and immune processes in the human lung in health and disease: evaluation by bronchoalveolar lavage. Am. J. Pathol. 97:149-206.
30. Semenzato, G. 1991. Immunology of interstitial lung diseases: cellular events taking place in the lung of sarcoidosis, hypersensitivity pneumonitis and HIV infection. Eur. Respir. J. 4:94-102.
31. Hara, I., S. Izui, and T. J. Dixon. 1982. Murine serum glycoprotein gp70 behaves as an acute phase reactant. J. Exp. Med. 155:345-357.
32. Zinkernagel, R. M., S. Cooper, J. Chambers, R. A. Lazzarini, H. Hengartner, and H. Arnheiter. 1990. Virus-induced autoantibody response to a transgenic viral antigen. Nature 345:68-71.
33. Daniele, R. P., P. M. Henson, J. C. Fantone, III, P. A. Ward, and R. B. Dreisin. 1981. Immune complex injury of the lung. Am. Rev. Respir. Dis. 124:738-755.
34. Dreisin, R. B., M. I. Schwarz, A. N. Theofilopoulos, and R. E. Stanford. 1978. Circulating immune complexes in the idiopathic interstitial pneumonias. N. Engl. J. Med 298:353-357.
35. Haslam, P. L., B. Thompson, I. Mohammed, P. J. Townsend, M. E. Hodson, E. J. Holborow, and M. Turner-Warwick. 1979. Circulating immune complexes in patients with cryptogenic fibrosing alveolitis. Clin. Exp. Immunol. 37:381-390.
36. Daniele, R. P., J. H. Dauber, and M. D. Rossman. 1980. Immunologic abnormalities in sarcoidosis. Ann. Intern. Med. 92:406-416.
37. Saint-Remy, J. R., D. N. Mitchell, and P. J. Cole. 1983. Variation in immunoglobulin levels and circulating immune complexes in sarcoidosis. Correlation with extent of disease and duration of symptoms. Am. Rev. Respir. Dis. 127:23-27.
38. Morrow, W. J. W., D. A. Isenberg, R. E. Sobol, R. B. Stricker, and T. Kieber-Emmons. 1991. AIDS virus infection and autoimmunity: a perspective of the clinical, immunological, and molecular origins of the autoallergic pathologies associated with HIV disease. Clin. Immunol. Immunopathol. 58:163-180.
39. Spurzem, J. R., C. Saltini, and R. G. Crystal. 1988. Functional significance of anti-T-lymphocyte antibodies in sarcoidosis. Am. Rev. Respir. Dis. 137: 600-605.
40. Talal, N., E. Flescher, and H. Dang. 1992. Evidence for possible retroviral involvement in autoimmune diseases. Ann. Allergy 69:221-224.
41. Ranki, A., P. Kurki, S. Riepponen, and E. Stephansson. 1992. Antibodies to retroviral proteins in autoimmune connective tissue disease: relation to clinical manifestations and ribonucleoprotein autoantibodies. Arthritis Rheum. 35:1483-1491.
42. Blomberg, J., O. Nived, R. Pipkorn, A. Bengtsson, D. Erlinge, and G. Sturfelt. 1994. Increased antiretroviral antibody reactivity in sera from a defined population of patients with systemic lupus erythematosus: correlation with autoantibodies and clinical manifestations. Arthritis Rheum. 37:57-66.
43. Mariette, X., P. Cherot, D. Cazals, C. Brocheriou, J. Brouet, and F. Agbalika. 1994. Antibodies to HTLV-1 in Sjögren's syndrome. Lancet 345:71. (Abstr.)
44. Carry, R. F., C. D. Fermin, D. J. Hart, S. S. Alexander, L. A. Donehower, and H. Luo-Zhang. 1990. Detection of a human intracisternal A-type retroviral particle antigenically related to HIV. Science 250:1127-1129.
45. Kalden, J. R., and S. Gay. 1994. Retroviruses and autoimmune rheumatic diseases. Clin. Exp. Immunol. 98:1-5.
46. Setoguchi, Y., S. Takahashi, T. Nukiwa, and S. Kira. 1991. Detection of human T-cell lymphotropic virus type I-related antibodies in patients with lymphocytic interstitial pneumonia. Am. Rev. Respir. Dis. 144: 1361-1365.