Apoptotic cells in peripheral blood from patients with low serum cobalamin

Journal of Submicroscopic Cytology and Pathology

Volumn 29, Issue 2, 1997, Pages 223-227

  Bunting, R W ^a   Selig, M K ^b   Dickersin, G R ^b  

^a A Red Sox Foundation and Massachusetts General Hospital Program   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Cobalamin deficiency

Indexed keywords

CYANOCOBALAMIN;

AGED; APOPTOSIS; ARTICLE; BLOOD; COMPARATIVE STUDY; CYANOCOBALAMIN DEFICIENCY; ELECTRON MICROSCOPY; FEMALE; HUMAN; LEUKOCYTE; MALE; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; REFERENCE VALUE; ULTRASTRUCTURE;

AGED; AGED, 80 AND OVER; APOPTOSIS; FEMALE; HUMANS; LEUKOCYTES; MALE; MICROSCOPY, ELECTRON; MIDDLE AGED; REFERENCE VALUES; VITAMIN B 12; VITAMIN B 12 DEFICIENCY;

EID: 0031110607     PISSN: 11229497     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. BAXTER G.D., COLLINS K.J., HARMON B.V., KUMAR S., PRENTICE R.L., SMITH P.J. and LAVIN M.F., 1989. Cell death by apoptosis in acute leukaemia. J. Pathol., 158, 123-129.
2. BLACKBURN E.K., CALLENDER S.T., DACIE J.V., DOLL R., GIRDWOOD R.H., MOLLIN D.L., SARACCI R., STAFFORD J.L., THOMPSON R.B., VARADE S. and WETHERLEY-MEIN G., 1968. Possible association between pernicious anaemia and leukaemia: A prospective study of 1,625 patients with a note on the very high incidence of stomach cancer. Int. J. Cancer, 3, 163-170.
3. BUNTING R.W., SELIG M.K. and DICKERSIN G.R., 1996. Ultrastructure of peripheral blood granulocytes from patients with low serum cobalamin. J. Submicrosc. Cytol. Pathol., 28, 187-195.
4. COHEN J.J., 1993. Apoptosis. Immunol. Today, 14, 126-130.
5. CORCINO J.J., ZALUSKY R., GREENBERG M. and HERBERT V., 1971. Coexistence of pernicious anaemia and chronic myeloid leukaemia: An experiment of nature involving vitamin B12 metabolism. Br. J. Hematol., 20, 511-520.
6. DOUGLAS A.S. and RIFKIND B.M., 1964. Megaloblastic anaemia in association with polycythemia vera. Scot. Med. J., 9, 469-473.
7. EDWIN E., 1967. The segmentation of polymorphonuclear neutrophils: The conditions in hypovitaminosis B12 and hypersegmentation. Acta Med. Scand., 182, 401-410.
8. GOULIAN M., BLEIBE B. and TSENG B.Y., 1980. Methotrexate-induced misincorporation of uracil into DNA. Proc. Natl. Acad. Sci. USA, 77 (4), 1956-1960.
9. HSING A.W., HANSSON L.E., MCLAUGHLIN J.K., NYREN O., BLOT W.J., EKBOM A. and FRAUMENI J.F. JR., 1993. Pernicious anemia and subsequent cancer. Cancer, 71, 745-750.
10. KERR J.F.R., WYLLIE A.H. and CURRIE A.R., 1972. Apoptosis: a basic biological phenomenon with wide-ranging implication in tissue kinetics. Br. J. Cancer, 26, 239-257.
11. LOO D.T., COPANI A., PIKE C.J., WHITTEMORE E.R., WALENCEWICZ A.J. and COTMAN C.W. 1993. Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proc. Natl. Acad. Sci. USA, 90, 7951-7955.
12. NATH B.J. and LINDENBAUM J., 1979. Persistence of neutrophil hypersegmentation during recovery from megaloblastic granulopoiesis. Ann. Intern. Med., 90, 757-760.
13. SACHS L. and LOTEM J., 1993. Control of programmed cell death in normal and leukemic cells: New implications for therapy. Blood, 82, 15-21.
14. SAVILL J.S., WYLLIE A.H., HENSON J.E. and HASLETT C., 1989. Macrophage phagocytosis of aging neutrophils in inflammation: Programmed cell death in the neutrophil leads to its recognition by macrophages. J. Clin. Invest., 83, 865-875.
15. SCHWARTZMAN R.A. and CIDLOWSKI J.A., 1993. Apoptosis: The biochemistry and molecular biology of programmed cell death. Endocr. Rev., 14, 133-151.
16. STABLER S.P., ALLEN R.H., SAVAGE D.G. and LINDENBAUM J., 1990. Clinical spectrum and diagnosis of cobalamin deficiency. Blood, 76, 871-881.
17. THOMPSON C.B., 1995. Apoptosis in the pathogenesis and treatment of disease. Science, 267, 1456-1462.
18. WRIGHT S.C., ZHONG J. and LARRICK J.W., 1994. Inhibition of apoptosis as a mechanism of tumor promotion. FASEB J., 8, 654-660.
19. WYLLIE A.H., 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature, 284, 555-556.
20. ZIV I., MELAMED E., NARDI N., LURIA D., ACHIRON A., OFFEN D. and BARZILAI A., 1994. Dopamine induces apoptosis-like cell death incultured chick sympathetic neurons - a possible novel pathogenetic mechanism in Parkinson's disease. Neurosci. Lett., 170, 136-140.
21. J. SUBMICROSC. CYTOL. PATHOL., 29 (2), 229-237, 1997