Synergistic inhibition of calcification of porcine aortic root with preincubation in FeCl3 and α-amino oleic acid in a rat subdermal model

Journal of Biomedical Materials Research

Volumn 38, Issue 1, 1997, Pages 43-48

  Chen, Weiliam ^a   Schoen, Frederick J ^b   Myers, David J ^c   Levy, Robert J ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c MEDTRONIC INC   (United States)

Author keywords

anticalcification; aortic cusp; aortic wall; cardiac valve prostheses; valvular disease

Indexed keywords

AGENTS; AMINO ACIDS; CALCIFICATION (BIOCHEMISTRY); DISEASES; IMPLANTS (SURGICAL); IRON COMPOUNDS; LIVING SYSTEMS STUDIES;

ANTICALCIFICATION; AORTIC CUSP; AORTIC WALL; RAT SUBDERMAL MODEL; VALVULAR DISEASE;

HEART VALVE PROSTHESES;

ALPHA AMINO ACID; FERRIC CHLORIDE; OLEIC ACID;

ANIMAL MODEL; ANIMAL TISSUE; AORTA ROOT; AORTA VALVE DISEASE; ARTERY CALCIFICATION; ARTICLE; BIOPROSTHESIS; CONTROLLED STUDY; HEART VALVE PROSTHESIS; HEART VALVE SURGERY; IMPLANTATION; NONHUMAN; PROSTHESIS FAILURE; RAT; SWINE;

ANIMALS; AORTA; CALCINOSIS; DISEASE MODELS, ANIMAL; EQUIPMENT FAILURE; FERRIC COMPOUNDS; HEART VALVE PROSTHESIS; OLEIC ACIDS; RATS; SWINE;

EID: 0031106023     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4636(199721)38:1<43::AID-JBM6>3.0.CO;2-H     Document Type: Article

References (28)

1. Schoen, F. J.; Levy, R. J.; Piehler, H. R. Pathological considerations in replacement cardiac valves. Cardiovasc. Pathol. 1:29-52; 1992.
2. Schoen, F. J.; Levy, R. J. Calcification of bioprosthetic heart valve. Bodnar, E.; Frater, R. eds. Replacement Heart Valves. New York: Pergamon Press; 1989:124-148.
3. Schoen, F. J.; Levy, R. J. Heart valve bioprostheses: antimineralization. Eur. J. Cardiothorac. Surg. 6[Suppl]:S91-S94; 1992.
4. Girardot, M. N.; Torriani, M.; Girardot, J. M. Role of glutaraldehyde in calcification of porcine heart valves: comparing cusp and wall. J. Biomed. Mater. Res. 29:793-801; 1995.
5. Girardot, M. N.; Torriani, M.; Girardot, J. M. Effect of AOA on glutaraldehyde-fixed bioprosthetic heart valve cusps and walls: binding and calcification studies. Int. J. Artif. Org. 17:76-82; 1994.
6. Girardot, M. N.; Girardot, J. M.; Schoen, F. J. Alpha amino oleic acid, a new compound, prevents calcification of bioprosthetic heart valve. Trans. Soc. Biomater. 14:114; 1991.
7. Chen, W.; Kim, J. D.; Schoen, F. J.; Levy, R. J. Effects of 2-amino oleic acid exposure conditions on the inhibition of calcification of glutaraldehyde cross-linked porcine aortic valve. J. Biomed. Mater. Res. 28:1485-1495; 1995.
8. Gott, J. P.; Pan, C.; Dorsey, L. M. A.; et al. Calcification of porcine valves: a successful new method of antimineralization. Ann. Thorac. Surg. 53:207-216; 1992.
9. Chen, W.; Schoen, F. J.; Levy, R. J. Mechanism of efficacy of 2-amino oleic acid for inhibition of calcification of glutaraldehyde pretreated porcine bioprosthetic heart valves. Circulation 90:323-329; 1994.
10. Woodroof, E. A. Use of glutaraldehyde and formaldehyde to process tissue heart valve. J. Bioeng. 2:1-9; 1978.
11. Cheung, D. T.; Nimni, M. E. Mechanism of cross-linking of proteins by glutaraldehyde: I reaction of model compounds. Connect. Tissue Res. 10:187-199; 1982.
12. Korn, A. H.; Feairheller, S. H.; Filachione, E. M. Glutaraldehyde: nature of the reagent. J. Mol. Biol. 65:525-529; 1972.
13. 3 in rat subdermal model studies. Am. J. Pathol. 138(4):971-981; 1991.
14. Levy, R. J.; Qu, X.; Underwood, T.; Schoen, F. J.; Trachy, J. W. Calcification of valved aortic allografts in rats: effects of age, crosslinking, and inhibitors. J. Biomed. Mater. Res. 29:217-226; 1995.
15. 3 preincubation. J. Biomed. Mater. Res. 25:906-935; 1991.
16. Girardot, M. N.; Girardot, J. M.; Schoen, F. J.; et al. Development of the AOA process as antimineralization treatment for bioprosthetic heart valves. Trans. Soc. Biomater. 16:266; 1993.
17. Schoen, F. J.; Levy, R. J.; Nelson, A. C.; Bernhard, W. F.; Nashef, A.; Hawley, M. Onset and progression of experimental bioprosthetic heart valve calcification. Lab. Invest. 52:523-532; 1985.
18. Schoen, F. J.; Tsao, J. W.; Levy, R. J. Calcification of bovine pericardium used in cardiac valve bioprostheses: implication for the mechanisms of bioprosthetic tissue mineralization. Am. J. Pathol. 123:134-145; 1986.
19. Karnovsky, M. J. A formaldehyde-glutaraldehyde fixative of high osmolality for use in electron microscopy. J. Cell Biol. 27:137A-138A; 1965.
20. Schoen, F. J.; Levy, R. J.; Nelson, A. C.; Bernhard, W. F.; Nashef, A.; Hawley, M. Onset and progression of experimental bioprosthetic heart valve calcification. Lab. Invest. 52:523-532; 1985.
21. Jones, M.; Eidbo, E. E.; Hilbert, S. L.; Ferrans, V. J.; Clarks, R. E. The effects of anticalcification treatments of bioprosthetic valves implanted in sheep. Trans. Am. Soc. Artif. Intern. Org. 34:1027-1030; 1988.
22. Hirsch, D. H.; Drader, J.; Thomas, T. J.; Schoen, F. J.; Levy, J. T.; Levy, R. J. Inhibition of calcification of glutaraldehyde pretreated porcine aortic cusps with sodium dodecyl sulfate: preincubation and controlled release studies. J. Biomed. Mater. Res. 27:1477-1484; 1993.
23. Christoffersen, M. R.; Thyregod, H. C.; Christoffersen, J. Effects of aluminum(III), chromium(III), and iron(III) on the rate of dissolution of calcium hydroxyapatite crystals in the absence and presence of the chelating agent desferrioxamine. Calcif. Tissue Int. 41:27-30; 1987.
24. Phelps, K. R.; Vigorita, V. J.; Bansal, M.; Einhorn, T. A. Histochemical demonstration of iron but not aluminum in a case of dialysis-associated osteomalacia. Am. J. Med. 84:775-780; 1988.
25. Urry, D. W. Neutral sites for calcium ion binding to elastin and collagen: a charge neutralization theory for calcification and its relationship to atherosclerosis. Proc. Natl. Acad. Sci. 68:810-814; 1971.
26. Urry, D. W.; Long, M. M. Molecular pathology of vascular elastic fiber - the importance of the glycoprotein coating. Glycoproteins and glycolipids in disease processes. ACS Symp. Ser. 80:227-255; 1978.
27. Cleveland, D. C.; Williams, W. G.; Razzouk, A. J.; et al. Failure of cryopreserved homograft valved conduits in the pulmonary circulation. Circulation 86(Suppl 5): 150-153; 1992.
28. Schoen, F. J. Differential calcification of cusps and aortic wall of failed stented porcine bioprosthetic valves. J. Biomed. Mater. Res. to appear.