A biosensor based on micromechanical interrogation of living cells

IEEE Engineering in Medicine and Biology Magazine

Volumn 16, Issue 2, 1997, Pages 66-72

  Antonik, Matthew D ^a,b,c,d   D'Costa, Neill P ^a,e,f   Hoh, Jan H ^a,g,h,i,j  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c UNIVERSITY OF MAINE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e HOWARD UNIVERSITY   (United States)

^f RUTGERS UNIVERSITY   (United States)

^g ILLINOIS STATE UNIVERSITY   (United States)

^h CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j UNIVERSITY OF BASEL   (Switzerland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CANTILEVERS; CELL GROWTH; EUKARYOTIC CELLS; MADINE DARBY CANINE KIDNEY CELLS; TOXINS;

ANALOG TO DIGITAL CONVERSION; ATOMIC FORCE MICROSCOPY; CELL CULTURE; CELLS; DATA ACQUISITION; MACHINE COMPONENTS; MECHANICAL PROPERTIES; MONOLAYERS;

BIOSENSORS;

AZIDE; MELITTIN;

ANIMAL CELL; ATOMIC FORCE MICROSCOPY; BIOSENSOR; CELL ACTIVITY; KIDNEY CELL; NONHUMAN; PERFORMANCE; REVIEW;

ADSORPTION; ANALOG-DIGITAL CONVERSION; ANIMALS; BIOCOMPATIBLE MATERIALS; BIOSENSING TECHNIQUES; BIVALVIA; CELLS, CULTURED; DATA COLLECTION; EQUIPMENT DESIGN; MICROSCOPY, ATOMIC FORCE; PROTEIN SORTING SIGNALS; PROTEINS; SURFACE PROPERTIES; TEMPERATURE;

EID: 0031104805     PISSN: 07395175     EISSN: None     Source Type: Journal    
DOI: 10.1109/51.582178     Document Type: Review

References (21)

1. Hikuma M, Obana H, Yasuda T: A potentiometric microbial sensor based on immobilized Escerchia coli for glutamic acid. Anal Chim Acta 116:61-67, 1980.
2. Bains W: A spectroscopically interrogated flow through type toxicity biosensor. Biosensors & Bioelectronics 9:111-117, 1994.
3. Tran-Minh C: Biosensors. Chapman & Hall, New York NY, p217, 1993
4. Owicki JC, Parce JW: Biosensors based on the energy metabolism of living cells: The physically chemistry and cell biology of extracellular acidification acidification. Biosensors & Bioelectronics 7:255-272, 1992.
5. Schear JB, Fishman HA, Albritton NL, Garigan D, Zare RN, et al.: Single cells as biosensors for chemical separation. Science 267:74-77, 1995.
6. Meyer G, Amer NM: Novel approach to atomic force microscopy. Appl Phys Lett 53:1045, 1988.
7. Alexander S, Hellemans L, Marti O, Schneir J, Elings V, et al.: An atomic-resolution atomic-force microscope implemented using an optical lever. J Appl Phys 65:164-167, 1989.
8. Thundat T, Warmack RJ, Chen GY, Allison DP: Thermal and ambient-induced deflections of scanning force microscope cantilevers. Appl Phys Lett 64:2894, 1994.
9. Radmacher M, Tillmann RW, Fritz M, Gaub HE: From molecules to cells: Imaging soft samples with the atomic force microscope. Science 257:1900-1905, 1992.
10. Barnes JR, Stephenson RJ, Woodburn CN, O'Seah SJ, Welland ME, et al.: A femtojoule calorimeter using micromechanical sensors. Rev Sci Inst 65:3793, 1994.
11. Radmacher M, Cleveland JP, Hansma PK: Improvement of thermally induced bending of cantilevers used for atomic force microscopy. Scanning 17:117-121, 1995.
12. Gimzewski JK, Gerber Ch, Meyer E, Schlittler RR: Observation of a chemical reaction using a micromechanical sensor. Chem Phys Lett 217:589, 1994.
13. Thundat T, Chen GY, Warmack RJ, Allison DP, Wachter EA: Vapor detection using resonating cantilevers. Anal Chem 67:519, 1995.
14. Thundat T, Wachter EA, Sharp SL, Warmack RJ: Detection of mercury vapor using resonating cantilevers. Appl Phys Lett 66:1695, 1995.
15. VanHaastert PJM: Transduction of the chemotactic cAMP signal across the plasma membrane of dictyostelium cells. Experientia 51:1144-1154, 1995
16. Bredt DS, Snyder SH: Nitric oxide: a physiological messanger molecule. Annual Rev of Biochemistry 63:175-95, 1994.
17. Cudmore S, Cossart P, Griffiths G, Way M: Actin-based motility of vaccina virus. Nature 378:636-638, 1995.
18. Olivieri M, Baier R, Loomis R: Surface properties of mussel adhesive protien component films. Biomaterials 13:1000-1008, 1992.
19. Schlichtler LC, Pennefather PS, van Staden CJ, Valentine EA: A perfused-cuvette method for flourimetric studies of non-adherent cells. Pflug Arch 421:400-402, 1992.
20. Cleveland JP, Schäffer TE, Hansma PK: Probing oscillatory hydration potentials using thermal-mechanical noise in an atomic force microscope. Phys Rev B 52:R8692-R8695, 1995.
21. Folkman J, Moscona A: Role of cell shape in growth control. Nature 273:345-8, 1978.