Synthesis and antifungal activity of two novel spermidine analogues

FEMS Microbiology Letters

Volumn 148, Issue 1, 1997, Pages 21-25

  Mackintosh, Caroline A ^a   Slater, Lindsay A ^b   McClintock, Carol A ^b   Walters, Dale R ^a   Havis, Neil D ^a   Robins, David J ^b  

^a SCOTTISH AGRICULTURAL COLLEGE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

antifungal; fungicide; spermidine analogue

Indexed keywords

FUNGICIDE; ORNITHINE; POLYAMINE; SPERMIDINE DERIVATIVE;

ANTIFUNGAL ACTIVITY; ARTICLE; BIOMASS; BIOSYNTHESIS; CONTROLLED STUDY; FUNGUS GROWTH; NONHUMAN; PEST CONTROL; PLANT; PRIORITY JOURNAL;

ANTIFUNGAL AGENTS; FOOD MICROBIOLOGY; FUNGI; HORDEUM; ROSALES; SPERMIDINE;

EID: 0031104644     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(97)00007-4     Document Type: Article

References (16)

1. Foster, S.A. and Walters, D.R. (1993) Fungicidal activity of the polyamine analogue, keto-putrescine. Pesticide Sci. 37, 267-272.
2. Havis, N.D., Walters, D.R., Foster, S.A., Martin, W.P., Cook, F.M. and Robins, D.J. (1994) Fungicidal activity of the synthetic putrescine analogue, (E)-1,4-diaminobut-2-ene, and derivatives. Pesticide Sci. 41, 61-69.
3. Havis, N.D., Walters, D.R., Martin, W.P., Cook, F.M. and Robins, D.J. (1994) Fungicidal activity of three putrescine analogues. Pesticide Sci. 41, 71-76.
4. Mackintosh, C.A. and Walters, D.R. (1996) Fungicidal activity of two spermidine analogues. J. Phytopathol. (in press).
5. Masse, J., Laberche, J.C. and Jeanty, G. (1988) The effects of nor-spermidine and dicyclohexylamine on in vitro potato development and free polyamines content. Plant Growth Reg. 7, 249-260.
6. McClintock, C.A.L. (1994) Synthesis and Biosynthesis of Quinolizidine Alkaloids with Enzyme Work. PhD Thesis, University of Glasgow.
7. 8-spermidine derivatives in cultured L1210 leukemia cells. Cancer Res. 45, 2050-2057.
8. Porter, C.W. and Sufrin, J.W. (1986) Interference with polyamine biosynthesis and/or function by analogs of polyamines or methionine as a potential anticancer chemotherapeutic strategy. Anticancer Res. 6, 525-542.
9. Prakash, N.J., Bowlin, T.L., Davis, G.F., Sunkara, P.S. and Sjoerdsma, A. (1988) Antitumour activity of norspermidine, a structural analogue of the natural polyamine, spermidine. Anticancer Res. 8, 563-568.
10. Rajam, M.V. and Galston, A.W. (1985) The effects of some polyamine biosynthetic inhibitors on growth and morphology of phytopathogenic fungi. Plant Cell Physiol. 26, 683-692.
11. Stevens, L. and Winther, M.D. (1979) Spermine, spermidine and putrescine in fungal development. Adv. Microb. Physiol. 19, 63-148.
12. Sunkara, P.S., Zwolshen, J.H., Prakash, N.J. and Bowlin, T.J. (1988) Mechanism of antitumour activity of norspermidine, a structural homologue of spermidine. In: Progress in Polyamine Research: Novel Biochemical, Pharmacological, and Clinical Aspects (Zappia, V. and Pegg, A.E., Eds.), pp. 707-716. Plenum Press, New York.
13. Walters, D.R. (1986) The effects of a polyamine biosynthesis inhibitor on infection of Vicia faba L. by the rust fungus, Uromyces viciae-fabae (Pers.) Schroet. New Phytol. 104, 613-619.
14. West, H.M. and Walters, D.R. (1988) The effects of polyamine biosynthesis inhibitors on infection of Hordeum vulgare L. by Erysiphe graminis f.sp. hordei Marchal. New Phytol. 110, 193-200.
15. West, H.M. and Walters, D.R. (1989) Effects of polyamine biosynthesis inhibitors on growth of Pyrenophora teres, Gaeumannomyces graminis, Fusarium culmorum and Septoria nodorum in vitro. Mycol. Res. 92, 453-457.
16. Walters, D.R., Keenan, J.P., Cowley, T., McPherson, A. and Havis, N.D. (1995) Inhibition of polyamine biosynthesis in Phytophthora infestans and Pythium ultimum. Plant Pathol. 44, 80-85.