Dichotomy of Blood- and Skin-Derived IL-4-Producing Allergen-Specific T Cells and Restricted Vβ Repertoire in Nickel-Mediated Contact Dermatitis

Journal of Immunology

Volumn 158, Issue 5, 1997, Pages 2500-2505

  Werfel, Thomas ^a   Hentschel, Michael ^a   Kapp, Alexander ^a   Renz, Harald ^b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; EPITOPE; GAMMA INTERFERON; INTERLEUKIN 4; LYMPHOCYTE ANTIGEN RECEPTOR; NICKEL; NICKEL SULFATE;

ARTICLE; BIOSYNTHESIS; BLOOD; CELL CLONE; DRUG EFFECT; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; METABOLISM; MULTIGENE FAMILY; SKIN; SKIN ALLERGY; T LYMPHOCYTE SUBPOPULATION;

ALLERGENS; CLONE CELLS; DERMATITIS, ALLERGIC CONTACT; EPITOPES; FEMALE; HUMANS; IMMUNOPHENOTYPING; INTERFERON TYPE II; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MULTIGENE FAMILY; NICKEL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SKIN; T-LYMPHOCYTE SUBSETS;

EID: 0031092697     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Romagnoli, P., A. M. Labhardt, and F. Sinigaglia. 1991. Selective interaction of Ni with an MHC-bound peptide. EMBO J. 10:1303.
2. Sinigaglia, F. 1994. The molecular basis of metal recognition by T cells. J. Invest. Dermatol. 102:398.
3. Al-Tawil, N. G., J. A. Marcusson, and E. Möller. 1981. Lymphocyte transformation test in patients with nickel sensitivity: an aid to diagnosis. Acta Derm. Venerol. 61:511.
4. +) carry the specificity and nickel sensitivity reaction in vitro in humans. J. Invest. Dermatol. 86:18.
5. Silvennoinen-Kassinen, S., I. Ikäheimo, J. Karvonen, M. Kauppinen, and M. Kallioinen. 1992. Mononuclear cell subsets in the nickel-allergic reaction in vitro and in vivo. J. Allergy Clin. Immunol. 89:794.
6. + T-lymphocyte clones from nickel contact allergic and non-allergic individuals. J. Invent. Dermatol. 98:59.
7. Sinigaglia, F., D. Scheidegger, G. Garotta, R. Scherper, M. Pletscher, and A. Lanzavecchia. 1985. Isolation and characterization of Ni-specific clones from patients with Ni-contact dermatitis. J. Immunol. 135:3929.
8. Daser, A., N. Meissner, U. Herz, and H. Renz. 1995. Role and modulation of T cell cytokines in allergy. Curr. Opin. Allergy. 7:762.
9. Sager, N., A. Feldmann, G. Schilling, P. Kreitsch, and C. Neumann. 1992. House dust mite-specific T cells in the skin of subjects with atopic dermatitis: frequency and lymphokine profile in the allergen patch test. J. Allergy Clin. Immunol. 89:801.
10. Werfel, T., A. Morita, M. Grewe, H. Renz, U. Wahn, J. Krutmann, and A. Kapp. 1996. Allergen specificity of skin-infiltrating T cells is not restricted to a type-2 cytokine pattern in chronic skin lesions of atopic dermatitis. J. Invest. Dermatol. 107:871.
11. Taswell, C. 1981. Limiting dilution assays for the determination of immunocompetent cell frequencies. J. Immunol. 126:1614.
12. Kalish, R. S., and K. L. Johnson. 1990. Enrichment and function of urushiol (poison ivy) specific T lymphocytes in lesions of allergic contact dermatitis to urushiol. J. Immunol. 145:3706.
13. Mosmann, T. R., and R. L. Coffmann. 1987. Two types of mouse helper T-cell clones: implications for immune regulation. Immunol. Today 8:223.
14. Cher, D. J., and T. R. Mosmann. 1987. Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones. J. Immunol. 138:3688.
15. Parronchi, P., D. Macchia, M. P. Piccinni, P. Biswas, C. Simonelli, E. Maggi, M. Ricci, A. A. Ansari, and S. Romagnani. 1991. Allergen-and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production. Proc. Natl. Acad. Sci. USA 88:4538.
16. + T cell clones. J. Immunol. 141:849.
17. Del Prete, G. F., M. De Carli, C. Mastromauro, R. Biagiotti, D. Macchia, P. Falagiani, M. Ricci, and S. Romagnani. 1991. Purified protein derivative (PPD) of Mycobacterium tuberculosis and excretory-secretory antigen(s) (TES) of Toxocara canis select human T cell clones with stable and opposite (TH1 or TH2) profile of cytokine production. J. Clin. Invest. 88:346.
18. + T lymphocytes in atopic patients. J. Immunol. 144:4651.
19. Estlander, T., L. Kanerva, O. Tupasela, H. Keskinen, and R. Jolanki. 1993. Immediate and delayed allergy to nickel with contact urticaria, rhinitis, asthma and contact dermatitis. Clin. Exp. Allergy 23:306.
20. Hamid, Q., M. Boguniewicz, and D. Y. M. Leung. 1994. Differential cytokine gene expression in acute vs chronic atopic dermatitis. J. Clin. Invest. 94:870.
21. Grewe, M., K. Gyufko, E. Schöpf, and J. Krutmann. 1994. Lesional expression of interferon-γ in atopic eczema. Lancet 343:25.
22. Grewe, M., S. Walther, K. Gyufko, W. Czech, E. Schöpf, and J. Krutmann. 1995. Analysis of the cytokine pattern expressed in situ in inhalant allergen patch test reactions of atopic dermatitis patients. J. Invest. Dermatol. 105:407.
23. Ohmen, J. D., J. M. Hanifin, B. J. Nickoloff, T. H. Rea, R. Wyzykowski, J. Kim, D. Jullien, T. McHugh, A. S. Nassif, S. C. Chan, and R. L. Modlin. 1995. Over-expression of IL-10 in atopic dermatitis: contrasting cytokine patterns with delayed-type hypersensitivity reactions. J. Immunol. 154:1956.
24. + T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion. J. Immunol. 144:4121.
25. van Loveren, H., K. Kato, D. Meade, D. Green, M. Horowitz, and W. Ptak. 1984. Characterization of two different Ly 1 T cell populations that mediate delayed type of hypersensitivity. J. Immunol. 133:2402.
26. Ralfkiaer, E., and G. L. Wantzin. 1984. In situ immunological characterization of the infiltrating cells in positive patch tests. Br. J. Dermatol. 111:13.
27. - cells that make TH2 cytokines and help B cells. Science 260:1802.
28. + cells can be primed in vitro to produce IL-4. J. Immunol. 148:1652.
29. Dunn, D. A., A.-S. Gadenne, S. Simha, E. A. Lerner, M. Bigby, and P. A. Bleicher. 1993. T-cell receptor Vβ expression in normal human skin. Proc. Natl. Acad. Sci. USA 90:1267.
30. Lewis, H. M., B. S. Baker, S. Bokth, A. V. Powles, J. J. Garioch, H. Valdimarsson, and L. Fry. 1993. Restricted T cell receptor Vβ gene usage in the skin of patients with guttate and chronic plaque psoriasis. Br. J. Dermatol. 129:514.
31. Leung, D. Y. M., P. Walsh, R. Giorno, and D. A. Norris. 1993. A potential role for superantigens in the pathogenesis of psoriasis. J. Invent. Dermatol. 100:225.
32. Renz, H., J. Saloga, K. L. Bradley, J. E. Loader, J. L. Greenstein, G. Larsen, and E. W. Gelfand. 1993. Specific V-β T cell subsets mediate the immediate hypersensitivity response to ragweed allergen. J. Immunol. 151:1907.
33. Renz, H., K. Bradley, J. Saloga, J. Loader, G. L. Larsen, and E. W. Gelfand. 1993. T cells expressing specific V-β elements regulate immunglobulin E production and airways responsiveness in vivo. J. Exp. Med. 177:1175.