Eosinophils Are Not Required for the Rejection of Neovascularized Fetal Pig Proislet Xenografts in Mice

Journal of Immunology

Volumn 158, Issue 5, 1997, Pages 2490-2499

  Simeonovic, Charmaine J ^a   Townsend, Michelle J ^a   Wilson, J Dennis ^b   McKenzie, Katja U S ^a   Ramsay, Alistair J ^a   Matthaei, Klaus I ^a   Mann, David A ^a   Young, Ian G ^a  

^a Biology and Environment   (Australia)

^b CANBERRA HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; INTERLEUKIN 3; MESSENGER RNA; MONOCLONAL ANTIBODY;

ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; CBA MOUSE; EOSINOPHIL; GENETIC TRANSCRIPTION; GENETICS; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOLOGY; MALE; METABOLISM; MOUSE; MOUSE MUTANT; NEOVASCULARIZATION (PATHOLOGY); NUDE MOUSE; PANCREAS ISLET; PANCREAS ISLET TRANSPLANTATION; PATHOLOGY; PATHOPHYSIOLOGY; STEM CELL; STEM CELL TRANSPLANTATION; SWINE; VASCULARIZATION; XENOGRAFT;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; CYTOKINES; EOSINOPHILS; GRAFT REJECTION; GRAFT SURVIVAL; INTERLEUKIN-3; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; RNA, MESSENGER; STEM CELL TRANSPLANTATION; STEM CELLS; SWINE; TRANSCRIPTION, GENETIC; TRANSPLANTATION, HETEROLOGOUS;

EID: 0031092639     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Coffman, R. L., B. W. P. Seymour, S. Hudak, J. Jackson, and D. Rennick. 1989. Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice. Science 24:308.
2. + B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity 4:15.
3. Corrigan, C. J., and A. B. Kay. 1992. T cells and eosinophils in the pathogenesis of asthma. Immunol. Today 13:501.
4. Walsh, R. E., and T. S. Gaginella. 1991. The eosinophil in inflammatory bowel disease. Scand. J. Gastroenterol. 26:1217.
5. Herndon, F. J., and S. G. Kayes. 1992. Depletion of eosinophils by anti-IL-5 monoclonal antibody treatment of mice infected with Trichinella spiralis does not alter parasite burden or immunologic resistance to reinfection. J. Immunol. 149: 3642.
6. Foster, P. S., S. P. Hogan, A. J. Ramsay, K. I. Matthaei, and I. G. Young. 1996. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J. Exp. Med. 183:1.
7. Corry, D. B., H. G. Folkesson, M. L. Warnock, D. J. Erle, M. A. Matthay, J. P. Wiener-Kronish, and R. M. Locksley. 1996. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J. Exp. Med. 183:109.
8. + T cell-depleted mice. Transplantation 49:849.
9. Morris, C. F., C. J. Simeonovic, M.-C. Fung, J. D. Wilson, and A. J. Hapel. 1995. Intragraft expression of cytokine transcripts during pig proislet xenograft rejection and tolerance in mice. J. Immunol. 154:2470.
10. Mandel, T. E., and M. Koulmanda. 1992. Survival of xeno-, allo-, and isografts in NOD and xenografts in other mouse strains following immunosuppression with anti-CD4 monoclonal antibody. Diabetes Nutr. Metab. 5(Suppl.):91.
11. + macrophage and not a T lymphocyte. Transplantation 60:594.
12. + T-lymphocytes in rejection by mice of fetal pig proislet xenografts. Diabetes 38(Suppl. 1):217.
13. Spry, C. J. F., A. B. Kay, and G. J. Gleich. 1992. Eosinophils. Immunol. Today 13:384.
14. Kopf, M., G. Le Gros, M. Bachmann, M. C. Lamers, H. Bluethmann, and G. Kohler. 1993. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 362:245.
15. Tepper, R. I., P. K. Pattengale, and P. Leder. 1989. Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell 57:503.
16. Lopez, A. F., C. J. Sanderson, J. R. Gamble, H. D. Campbell, I. G. Young, and M. A. Vadas. 1988. Recombinant human interleukin 5 is a selective activator of human eosinophil function. J. Exp. Med. 167:219.
17. Dialynas, D. P., Z. S. Quan, K. A. Wall, A. Pierres, J. Quintans, M. R. Loken, M. Pierres, and F. W. Fitch. 1983. Characterization of the murine T cell surface molecule designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule. J. Immunol. 131:2445.
18. Abrams, J. S., and M. K. Pearce. 1988. Development of rat anti-mouse interleukin 3 monoclonal antibodies which neutralize bioreactivity in vitro. J. Immunol. 140: 131.
19. Kirkman, R. L., R. B. Colvin, M. W. Flye, G. S. Leight, S. A. Rosenberg, G. M. Williams, and D. H. Sachs. 1979. Transplantation in miniature swine. VI. Factors influencing survival of renal allografts. Transplantation 28:18.
20. +) subsets among anti-la cytolytic T cell clones. J. Immunol. 132:2775.
21. Ledbetter, J. A., and L. A. Herzenberg. 1979. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 47:63.
22. Warren, H. S., M. J. Hodder, W. Allan, D. A. Hume, and C. J. Simeonovic. 1992. Induction of class II major histocompatibility antigens on thyroid, adult pancreatic islet and fetal proislet allografts. Transplantation 53:834.
23. Lille, R. D., ed. 1977. H. J. Conn's Biological Stains, 9th Ed., Ch. 6. Williams & Wilkins, Baltimore, p. 109.
24. Emmel, V. M., and E. V. Cowdry, eds. 1970. Laboratory technique in biology and medicine. Robert E. Krieger Publishing Co., Inc., Huntington, p. 404.
25. Chirgwin, J. M., A. E. Przybyla, R. J. MacDonald, and W. J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294.
26. Warner, N. L., M. A. S. Moore, and D. Metcalf. 1969. A transplantable myelomonocytic leukemia in BALB/c mice: cytology, karyotype and muramidase content. J. Natl. Cancer Inst. 43:963.
27. Ralph, P., M. A. S. Moore, and K. Nilsson. 1976. Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines. J. Exp. Med. 143:1528.
28. Kaye, J., S. Porchelli, J. Tite, B. Jones, and C. A. Janeway, Jr. 1983. Both a mono-clonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells. J. Exp. Med. 158:836.
29. Montgomery, R. A., and M. J. Dallman, M. J. 1991. Analysis of cytokine expression during fetal thymic ontogeny using the polymerase chain reaction. J. Immunol. 147:554.
30. + T cell-depleted diabetic mice. Transplantation 50:657.
31. Martinez, O. M., N. L. Ascher, L. Ferrell, J. Villanueva, J. Lake, J. P. Roberts, and S. M. Krams. 1993. Evidence for a nonclassical pathway of graft rejection involving interleukin 5 and eosinophils. Transplantation 55:909.
32. Forster, P., H. N. Sankary, M. Hart, M. Ashman, and J. W. Williams. 1989. Blood and graft eosinophilia as predictors of rejection in human liver transplantation. Transplantation 47:72.
33. Kormendi, F., and W. J. C. Amend. 1988. The importance of eosinophil cells in kidney allograft rejection. Transplantation 45:537.
34. Weir, J. R., M. Craggs-Hall, S. Y. Shen, J. N. Posner, S. V. Alongi, F. J. Dagher, and J. H. Sadler. 1986. The prognostic value of the eosinophil in acute renal allograft rejection. Transplantation 41:709.
35. Sher, A., R. L. Coffman, S. Hieny, and A. W. Cheever. 1990. Ablation of eosinophil and IgE responses with anti-IL-5 or anti-IL-4 antibodies fails to affect immunity against Schistosoma mansoni in the mouse. J. Immunol. 145:3911.
36. + T cells, IL-5, and mast cells, Clin. Immunol. Immunopathol. 73:305.
37. + T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea. Am. Rev. Respir. Dis. 146:374.
38. Schumacher, J. H., A. O'Garra, B. Schrader, A. van Kimmenade, M. M. Bond, T. R. Mosmann, and R. T. Coffman. 1988. The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. J. Immunol. 141:1576.
39. Dent, L. A., M. Strath, A. L. Mellor, and C. J. Sanderson. 1990. Eosinophilia in transgenic mice expressing interleukin 5. J. Exp. Med. 172:1425.
40. Teixeira, M. M., T. J. Williams, and P. G. Hellewell. 1995. Mechanisms and pharmacological manipulation of eosinophil accumulation in vivo. Trends Pharmacol. Sci. 16:418.
41. Rothenberg, M. E., A. D. Luster, and P. Leder. 1995. Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression. Proc. Natl. Acad. Sci. USA 92:8960.
42. Tepper, R. I., R. L. Coffman, and P. Leder. 1992. An eosinophil-dependent mechanism for the antitumor effect of interleukin-4. Science 257:548.
43. Hayashi, M., O. M. Martinez, R. Garcia-Kennedy, S. So, C. O. Esquivel, and S. M. Krams. 1995. Expression of cytokines and immune mediators during chronic liver allograft rejection. Transplantation 60:1533.
44. Kita, H., S. Sur. L. W. Hunt, E. S. Edell, D. A. Weiler, M. C. Swanson, R. W. Samsel, J. S. Abrams, and G. J. Gleich. 1996. Cytokine production at the site of disease in chronic eosinophilic pneumonitis. Am. J. Respir. Crit. Care Med. 153: 1437.
45. + T cells secreting Th1 orTh2 cytokines. Immunity 2:271.
46. Wogensen, L., H. Xiaojian, and N. Sarvetnick. 1993. Leukocyte extravasation into the pancreatic tissue in transgenic mice expressing interleukin 10 in the islets of Langerhans. J. Exp. Med. 178:175.
47. + T helper cells and self antigen-presenting cells in the mouse. J. Exp. Med. 172:567.
48. Yoshizawa, K., and A. Yano. 1984. Mouse T lymphocytes proliferative responses specific for human MHC products in mouse anti-human xenogeneic MLR. J. Immunol. 132:2820.
49. Del Pozo, V., B. De Andres, E. Martin, B. Cardaba, J. C. Fernandez, S. Gallardo, P. Tramon, F. Leyva-Coblan, P. Palomino, and C. Lahoz. 1992. Eosinophil as antigen-presenting cell: activation of T cell clones and T cell hybridoma by eosinophils after antigen processing. Eur. J. Immunol. 22:1919.
50. Lopez, A. F., C. J. Strath, and C. J. Sanderson. 1981. IgG and complement receptors on purified mouse eosinophils and neutrophils. Immunology 43:779.