Apoptosis and Response to Radiation: Implications for Radiation Therapy

ONCOLOGY

Volumn 11, Issue 3, 1997, Pages 349-356

  Meyn, Raymond E ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOCARCINOMA; ANIMAL; APOPTOSIS; FEMALE; HUMAN; MITOSIS; OVARY TUMOR; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; REVIEW;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; MITOSIS; OVARIAN NEOPLASMS; RADIATION DOSAGE;

EID: 0031091336     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Kerr JFR, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide ranging implications in tissue kinetics. Br J Cancer 26:239-257, 1972.
2. Wyllie A. Apoptosis (The 1992 Frank Rose Memorial Lecture). Br J Cancer 67:205-208, 1992.
3. Peters LJ, Brock WA, Johnson T, et al: Potential methods for predicting tumor radiocurability Int J Radiat Oncol Biol Phys 12:459-467, 1986.
4. Fertil B, Malaise EP: Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors: Analysis of 101 published survival curves. Int J Radiat Oncol Biol Phys 11:1699-1707, 1985
5. Coleman CN: Beneficial liaisons Radiobiology meets cellular and molecular biology. Radiother Oncol 28:1-15, 1993.
6. Puck TT, Marcus PI: Action of x-rays on mammalian cells. J Exp Med 103:653-666, 1956
7. Bacq ZM, Alexander P Fundamentals of Radiobiology, pp 248-252. London, Pergamon Press, 1961
8. Schreck R Cinemicrographic observations and theoretical considerations on reactions of lymphocytes to x-rays. Radiology 65:912-919, 1955.
9. Dewey WC, Ling CC, Meyn RE: Radiation-induced apoptosis: Relevance to radiotherapy. Int J Radiat Oncol Biol Phys 33:781-796, 1995
10. Radford IR: Mouse lymphoma cells that undergo interphase death show markedly increased sensitivity to radiation-induced DNA double-strand breakage as compared with cells that undergo mitotic death. Int J Radiat Oncol Biol Phys 59:1353-1369, 1991.
11. Radford IR: Radiation response of mouse lymphoid and myeloid cell lines: Part I: Sensitivity to killing by ionizing radiation, rate of loss of viability, and cell type of origin. Int J Radiat Biol 65:203-215, 1994
12. Aldridge DR, Arends MJ, Radford IR: Increasing the susceptibility of the rat 208 fibroblast cell line to radiation-induced apoptosis does not alter its clonogic survival dose-response. Br J Cancer 71:571-577, 1995.
13. Kerr JFR, Searle J: Apoptosis: Its nature and kinetic role, in Meyn RE and Withers HR (eds): Radiation Biology in Cancer Research, pp 367-384. New York, Raven Press, 1980.
14. Pratt NE, Sodicoff M: Ultrastructural injury following X-irradiation of rat parotid gland acinar cells. Arch Oral Biol 17:1177-1186, 1972.
15. Potten C: Extreme sensitivity of some intestinal crypt cells to X and γ irradiation. Nature 269:518-521, 1977.
16. Stephens LC, Schultheiss TE, Ang KK, et al: Pathogenesis of radiation injury to the salivary glands and potential methods of protection. Cancer Bull 41:106-114, 1989.
17. Stephens LC, Ang KK, Schultheiss TE, et al: Target cell and mode of radiation injury in Rhesus salivary glands. Radiother Oncol 7:165-174, 1986.
18. Stephens LC, Ang KK, Schultheiss TE, et al: Apoptosis in irradiated murine tumors. Radiat Res 127:308-316, 1991.
19. Stephens LC, Hunter NR, Ang KK, et al: Development of apoptosis in irradiated murine tumors as a function of time and dose. Radiat Res 135:75-80, 1993.
20. Meyn RE, Stephens LC, Ang KK, et al: Heterogeneity in the development of apoptosis in irradiated murine tumours of different histologies. Int J Radiat Biol 64:583-591, 1993.
21. Meyn RE, Stephens LC, Hunter NR, et al: Reemergence of apoptotic cells between fractionated doses in irradiated murine tumors. Int J Radiat Oncol Biol Phys 30:619-624, 1994.
22. Meyn RE, Stephens LC, Milas L: Programmed cell death and radioresistance. Cancer Metastasis Rev 15:119-131, 1996.
23. Story MD, Voehringer DW, Malone CG, et al: Radiation-induced apoptosis in sensitive and resistant cells isolated from a mouse lymphoma. Int J Radiat Biol 66:659-668, 1994.
24. Peter ME, Kischkel FC, Hellbardt S, et al: CD95 (APO-1/Fas)-associating signalling proteins Cell Death and Differentiation 3:161-170, 1996.
25. Barinaga M: Forging a path to cell death. Science 273:735-737, 1996.
26. Gulbins E, Bissonnette R, Mahboubi A, et al: FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway. Immunity 2:341-351, 1995.
27. Saba JD, Obeid LM, Hannun YA Ceramide: an intracellular mediator of apoptosis and growth supression. Phil Trans R Soc Lond B 351:233-244, 1996.
28. Haimovitz-Friedman A, Kan C-C, Ehleiter D, et al: Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J Exp Med 180:525-535, 1994
29. Tomei L, Kanter P, Wenner C. Inhibition of radiation-induced apoptosis in vitro by tumor promotors. Biochem Biophys Res Commun 155-324-331, 1988.
30. Uckun FM, Tuel-Ahlgren L, Song CW, et al: Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell death. Proc Natl Acad Sci USA 89:9005-9009, 1992.
31. Lowe S, Schmitt E, Smith S, et al: p53 is required for radiation-induced apoptosis in mouse thymocytes Nature (London) 362:847-849, 1993.
32. Clarke AR, Purdie CA, Harrison DJ, et al: Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature (London) 362:849-852, 1993
33. Sentman CL, Shutter JR, Hockenberry D, et al: Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67:879-888, 1991.
34. Strasser A, Harris A, Cory S: Bcl-2 transgene inhibits T cell death and perturbs thymic self censorship. Cell 67:889-899, 1991.
35. Kastan M, Zhan W, El-Deiry W, et al: A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 71:587-597, 1992.
36. Evan GI, Wyllie AH, Gilbert CS, et al: Induction of apoptosis in fibroblasts by c-myc protein. Cell 69:119-128, 1992.
37. Chcn CH, Zhang J and Ling CC: Transfected c-myc and c-Ha-ras modulate radiation-induced apoptosis in rat embryo cells. Radiat Res 139:307-315, 1994.
38. Wyllie A, Rose K, Morris R, et al: Rodent fibroblast tumours expressing human myc and ras genes: Growth, metastasis and endogenous oncogene expression. Br J Cancer 56:251-259, 1987.
39. Wheeler JA, Stephens LC, Eifel P, et al: Apoptosis as a predictor of tumor response to radiation in stage IB cervical adenocarcinoma. Int J Radiat Oncol Biol Phys 32 1487-1493, 1995.
40. Chyle V, Pollack A, Czerniak BA, et al: Apoptosis and downstaging after preoperative radiotherapy for muscle-invasive bladder cancer. Int J Radiat Oncol Biol Phys 35:281-287, 1996.
41. Levine EL, Davidson SE, Roberts SA, et al: Apoptosis as predictor of response to radiotherapy in cervical carcinoma. Lancer 344:472, 1994.
42. Spitz FR, Nguyen D, Skibber JM, et al: Adenoviral-mediated wild-type p53 gene expression sensitized colorectal cancer cells to ionizing radiation. Clin Cancer Res 2:1665-1671, 1996.
43. Fukunaga-Johnson N, Gelino EA, Benedict M, et al: Bcl-xs adenovirus-mediated gene therapy approach sensitizes cancer cells to radiation-induced apoptosis. Int J Radiat Oncol Biol Phys 36:191, 1996.
44. Wang C-Y, Mayo MW, Baldwin AS: TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kB. Science 274:784-787, 1996.
45. Wu X, Fan Z, Masui H, et al: Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin. J Clin Invest 95:1897-1905, 1995.