Doxymycine-cyanoacrylate treatment of recurrent aphthous ulcers

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics

Volumn 83, Issue 3, 1997, Pages 329-333

  Ylikontiola, L ^a,b   Sorsa, T ^c   Hayrinen Immonen R ^c   Salo, T ^a  

^a UNIVERSITY OF OULU   (Finland)

^b OULU UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; CYANOACRYLATE DERIVATIVE; DOXYCYCLINE; DRUG DERIVATIVE; ISODENT; NONSTEROID ANTIINFLAMMATORY AGENT; TISSUE ADHESIVE;

ADULT; APHTHOUS STOMATITIS; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FACE PAIN; FEMALE; HUMAN; MALE; MIDDLE AGED; PAIN ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ADULT; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYANOACRYLATES; DOXYCYCLINE; FACIAL PAIN; FEMALE; HUMANS; MALE; MIDDLE AGED; PAIN MEASUREMENT; STOMATITIS, APHTHOUS; TISSUE ADHESIVES;

EID: 0031089417     PISSN: 10792104     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1079-2104(97)90238-9     Document Type: Article

References (36)

1. Hay KD, Reade PC. The use of an elimination diet in the treatment of recurrent aphtous ulceration of the oral cavity. Oral Surg Oral Med Oral Pathol 1984;57:504-7.
2. Antoon JW, Miller RL. Aphtous ulcers: a review of the literature on etiology, pathogenesis, diagnosis, and treatment. J Am Dent Assoc 1980;101:803-8.
3. Pedersen A. Psychologic stress and recurrent aphtous ulceration. J Oral Pathol Med 1989;18:119-22.
4. Graykowski EA, Baile MF, Lee WB, Stanley HR. Recurrent aphtous stomatitis, clinical, therapeutic, histopathologic, and hypersensitivity aspects. JAMA 1966;196:637-44.
5. Miller MF, Garfunkle AA, Ram CA, Ship J II. The inheritance of recurrent aphtous stomatitis, observations and susceptibility. Oral Surg Oral Med Oral Pathol 1980;49:409-12.
6. Pedersen A, Klausen B, Hougen HP, Stenvang JP. T-lymphocyte subsets in recurrent aphtous ulceration. J Oral Pathol Med 1989;18:59-60.
7. Axell T, Henricsson V. The occurence of recurrent aphtous ulcers in an adult Swedish population. Acta Odontol Scand 1985;43:121-5.
8. Greenspan JS, Gadol N, Olson JA, Hoover CI, Jacobsen PL, Shillitoe EJ, et al. Lymphocyte function in recurrent aphtous ulceration. J Oral Pathol 1985;14:592-602.
9. Ship J II, Morris AL, Durocher RT, Burket LW. Recurrent aphtous ulcerations in a professional school student population: twelve-month study of natural disease patterns. Oral Surg Oral Med Oral Pathol 1961;14:30-9.
10. Häyrinen-Immonen R, Nordström D, Malmström M, Hietanen J, Konttinen YT. Immune-inflammatory cells in recurrent oral ulcers (ROU). Scand J Dent Res 1991;99:510-8.
11. Porter SR, Scully C. Aphtous stomatitis: an overview of ethiopathogenesis and management. Clin Exp Dermatol 1991;16:235-43.
12. Matthews RW, Scully CM, Levers BHG, Hislop WS. Clinical evaluation of benzydamine, chlorhexidine, and placebo mouthwashes in the management of recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol 1987;63:189-91.
13. Potoky JR. Recurrent aphthous stomatitis: a proposed therapeutic regimen. J Oral Med 1981;36:44-6.
14. Miles DA, Bricker SL, Razmus TF. Triamcinolone acetonide versus chlorhexidine for treatment of recurrent stomatitis. Oral Surg Oral Med Oral Pathol 1993;75:397-402.
15. Cooke BED. The diagnosis of bullous lesions affecting the oral mucosa. Br Dent J 1960;109:83-96.
16. Conklin RJ, Blasberg B. Common inflammatory diseases of the mouth. Int J Dermatol 1991;30:323-35.
17. Golub JL, Ciancio S, Ramamurthy NS, Leung M, McNamara TF. Low dose doxycycline therapy: effect on gingival and crevicular fluid collagenase activity in humans. J Periodontol 1990;25:321-30.
18. Sorsa T, Ding Y, Salo T, et al. Effects of tetracyclines on neutrophil, gingival, and salivary collagenases. Ann N Y Sci 1994;732:112-31.
19. Lauhio A, Sao T, Tjäderhane L, Lähdevirta J, Golub LM, Sorsa T. Tetracyclines in treatment of rheumatoid arthritis. Lancet 1995;346:645-6.
20. Golup LM, Sorsa T, Lee H-M, Ciancio S, Ramamurthy NS, Gruber B, et al. Doxymycine inhibits neutrophil (PMN)-type matrix metalloproteinases in human adult periodontis gingiva. J Clin Periodontol 1995;22:100-9.
21. Lauhio A, Sorsa T, Lindy O, Sudmalainen K, Saari H, Golub LM. The anticollagenolytic potential of lymecycline in the long term treatment of reactive arthritis. Arthritis Rheum 1992;35:195-8.
22. Ramamurthy NS, Vernillo AT, Greenwald RA, Lee H-M, Sorsa T, Golub LM, et al. Reactive oxygen species activate and tetracycline inhibits rat osteoblast collagenase. J Bone Min Res 1993;8:1247-53.
23. Birkedahl-Hansen H, Moore W, Bodden M, Windsor L, Birkedahl-Hansen B, DeCarlo A, et al. Matrix metalloprotinases: a review. Crit Rev Oral Biol Med 1993; 4:197-250.
24. Weiss SJ. Tissue destruction by neutrophils. N Engl J Med 1989;320:365-76.
25. Konttinen YT, Lindy O, Kemppinen P. Collagenase reserves in polymorphonuclear neutrophil leukocytes from synovial fluid and peripheral blood of patients with rheumatoid arthritis. Matrix 1991;11:296-301.
26. Häyrinen-Immonen R, Sorsa T, Pettilä J, Konttinen YT, Teronen O, Malmström M. Effect of tetracyclines on collagenase activity in patients with recurrent aphthous ulcers. J Oral Pathol Med 1994;23:269-72.
27. Golup LM, Suomalainen K, Sorsa T. Host modulation with tetracyclines and their chemically modified analogues. Curr Opin Dent 1992;2:80-90.
28. Häyrinen-Immonen R, Sorsa T, Nordström D, Malmström M, Konttinen YT. Collagenase and stromelysin in recurrent aphthous ulcers (RAU). Int J Oral Maxillofac Surg 1993;22:46-9.
29. Diekmann O, Tschesche H. Degradation of kinins, angiotensins, and substance P by polymorphonuclear matrix metalloproteinases MMP-8 and MMP-9. Braz J Med Biol Res 1994;8:1865-7.
30. Sorsa T. Activation of latent collagenase purified from human leukocytes. Scand J Rheumatol 1987;16:167-75.
31. Suomalainen K. Interstitial collagenases in gingival crevicular fluid and saliva in periodontal diseases. Helsinki, Finland: University of Helsinki; 1993.
32. Lauhio A, Salo T, Ding Y. In vivo inhibition of human neutrophil collagenase (MMP-8) activity during long-term combination therapy of doxycycline and nonsteroidal antiinflammatory drugs (NSAID) in acute reactive arthritis. Clin Exp Immunol 1994;98:21-8.
33. Smith GN, Brandt K, Hasty KA. Procollagenase is reduced to inactive lower molecular species upon activation in the presence of doxycycline. Ann N Y Acad Sci 1994;732:436-8.
34. Uitto V-J, Firth JD, Nip L, Golup LM. Doxycycline and chemically modified tetracycline inhibit gelatinase A (MMP-2) gene expression in human skin keratinocytes. Ann N Y Acad Sci 1994;732:140-51.
35. Gabler WL, Creamer HR. Suppression of human neutrophil functions by tetracyclines. J Periodontal Res 1991;26:52-8.
36. Wasil M, Halliwell B, Moonhouse CP. Scavenging of hypochlorous acid by tetracycline, rifampicin and some other antibiotics: a possible antioxidant action of rifampicin and tetracycline. Biochem Pharmacol 1981;37:775-84.