Multiple endocrine neoplasia type 2A in a black South African family

South African Medical Journal

Volumn 87, Issue 3 SUPPL., 1997, Pages 371-372

  Hopley, M ^a   Huddle, K R L ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

DROSOPHILA PROTEIN; ONCOPROTEIN; PROTEIN RET; PROTEIN TYROSINE KINASE; RET ONCOGENE PROTEIN, DROSOPHILA;

ADULT; ARTICLE; CASE REPORT; FEMALE; GENETICS; HUMAN; MALE; NEGRO; PEDIGREE; POINT MUTATION; SIPPLE SYNDROME;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; DROSOPHILA PROTEINS; FEMALE; HUMANS; MALE; MULTIPLE ENDOCRINE NEOPLASIA TYPE 2A; PEDIGREE; POINT MUTATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RET; RECEPTOR PROTEIN-TYROSINE KINASES;

EID: 0031086141     PISSN: 02569574     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Sobol H, Narod SA, Nakamura Y, et al. Screening for multiple endocrine neoplasia type 2a with DNA-potymorphism analysis. N Engl J Med 1989; 321: 996-1001.
2. Mulligan LM, Eng C, Healy CS, et al. Germ-line mutations of the RET protooncogene in multiple endocrine neoplasia type 2A. Nature 1993; 363: 458-460.
3. Donis-Keller H, Dou S, Chi D, et al. Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC. Hum Mol Genet 1993; 2: 851-856.
4. Kwok JBJ, Gardner E, Warner JP, Ponder BAJ, Mulligan LM. Structural analysis of the human RET proto-oncogene using exon trapping. Oncogene 1993; 8: 2575-2582.
5. Iwamoto T, Taniguchi M, Asai N, Ohkusu K, Nakashima I, Takahashi M. cDNA cloning of mouse RET proto-oncogene and its sequence similarity to the cadherin superfamily. Oncogene 1993; 8: 1087-1091.
6. Eng C. The RET proto-oncogene in multiple endocrine neoplasia type 2 and Hirschprung's disease. N Engl J Med 1996; 335: 943-951.
7. Utiger RD. Medullary thyroid carcinoma, genes, and the prevention of cancer. N Engl J Med 1994; 331: 870-871.
8. Lips CJM, Landsvater RM, Höppener JWM, et al. Clinical screening as compared with DNA analysis in families with multiple endocrine neoplasia type 2A. N Engl J Med 1994; 331: 828-835.
9. Wells SA jun, Chi DD, Toshima K, et al. Predictive DNA testing and prophylactic thyroidectomy in patients at risk for multiple endocrine neoplasia type 2A. Ann Surg 1994; 220: 237-250.
10. Easton DF, Ponder MA, Cummings T, et al. The clinical and screening age-at-onset distribution for the MEN 2 syndrome. Am J Hum Genet 1989; 44: 208-215.
11. Ponder BAJ, Ponder MA, Coffey R, et al. Risk estimation and screening in families of patients with medullary thyroid carcinoma. Lancet 1988; 1: 397-401.