Itraconazole plasma and tissue concentrations in the spiny lizard (Sceloporus sp.) following once-daily dosing

Journal of Zoo and Wildlife Medicine

Volumn 28, Issue 1, 1997, Pages 89-93

  Gamble, Kathryn C ^a   Alvarado, Tom P ^a   Bennett, Cynthia L ^a  

^a Dallas Zoological Society   (United States)

Author keywords

Antifungals; Itraconazole; Lizard; Sceloporus

Indexed keywords

ANTIFUNGAL AGENT; ITRACONAZOLE;

ANIMAL; ARTICLE; BLOOD; CHEMISTRY; FEMALE; LIVER; LIZARD; MALE; METABOLISM; MUSCLE; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ANIMALS; ANTIFUNGAL AGENTS; FEMALE; ITRACONAZOLE; LIVER; LIZARDS; MALE; MUSCLES;

EID: 0031085611     PISSN: 10427260     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Espinel-Ingroff, A., S. Shadomy, and R. J. Gebhart. 1984. In vitro studies with R 51,211 (itraconazole). Antimicrob. Agents Chemother. 26: 5-9.
2. Grant, S. M., and S. P. Clissold. 1989. Itraconazole: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in superficial and systemic mycoses. Drugs 37: 310-344.
3. Hardin, T. C., J. R. Graybill, R. Fetchick, R. Woestenborghs, M. G. Rinaldi, and J. G. Kuhn. 1988. Pharmacokinetics of itraconazole following oral administration to normal volunteers. Antimicrob. Agents Chemother. 32: 1310-1313.
4. Heykants, J., A. Van Peer, K. Lavrijsen, W. Meuldermans, R. Woestenborghs, and G. Cauwenbergh. 1990. Pharmacokinetics of oral antifungals and their clinical implications. Br. J. Clin. Pract. 44(9 Suppl. 71): 50-56.
5. Heykants, J., A. Van Peer, V. Van de Velde, P. Van Rooy, W. Meuldermans, K. Lavrijsen, R. Woestenborghs, J. Van Cutsem, and G. Cauwenbergh. 1989. The clinical pharmacokinetics of itraconazole: an overview. Mycoses 32(Suppl. 1): 67-87.
6. Jones, M. P., S. E. Orosz, and D. L. Frazier. 1995. Evaluation of the pharmacokinetic disposition of itraconazole in red-tailed hawks (Buteo jamaicensis). Proc. Assoc. Avian Vet. 1995: 19-20.
7. Mader, D. R. (ed.). 1996. Reptile Medicine and Surgery. W. B. Saunders Co., Philadelphia, Pennsylvania.
8. Meinhof, W. 1993. Kinetics and spectrum of activity of oral antifungals: the therapeutic implications. J. Am. Acad. Dermatol. 29: S37-S41.
9. Orosz, S. E., E. C. Schroeder, and D. L. Frazier. 1994. Itraconazole: a new antifungal for birds. Proc. Assoc. Avian Vet. 1994: 13-16.
10. Page, C. D., M. Mautino, H. Derendorf, and W. Mechlinski. 1991. Multiple-dose pharmacokinetics of ketoconazole administered orally to gopher tortoises (Gopherus polyphemus). J. Zoo Wildl. Med. 22: 191-198.
11. Perfect, J. R., D. V. Savani, and D. T. Durack. 1993. Uptake of itraconazole by alveolar macrophages. Antimicrob. Agents Chemother. 37: 903-904.
12. Van Cutsem, J., F. Van Gerven, M. Van de Ven, M. Borgers, and P. A. J. Janssen. 1984. Itraconazole, a new triazole that is orally active in aspergillosis. Antimicrob. Agents Chemother. 26: 527-534.
13. Warnock, D. W., A. Turner, and J. Burke. 1988. Comparison of high performance liquid chromatographic and microbiological methods for determination of itraconazole. J. Antimicrob. Chemother. 21: 93-100.
14. Wishart, J. M. 1987. The influence of food on the pharmacokinetics of itraconazole in patients with superficial fungal infections. J. Am. Acad. Dermatol. 17: 220-223.