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Volumn 3, Issue 3, 1997, Pages 108-115

Liver regeneration: Prospects for therapy based on new technologies

Author keywords

[No Author keywords available]

Indexed keywords

ARTIFICIAL LIVER; CELL TRANSPLANTATION; GENE THERAPY; GENETIC DISORDER; HUMAN; LIVER DISEASE; LIVER REGENERATION; MOLECULAR BIOLOGY; REVIEW; STEM CELL;

EID: 0031084808     PISSN: 13574310     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-4310(96)10062-9     Document Type: Review
Times cited : (41)

References (49)
  • 1
    • 0002676493 scopus 로고
    • Liver regeneration
    • (Arias, I. et al., eds), Raven Press
    • 1 Fausto, N. and Webber, E. (1994) Liver regeneration, in The Liver: Biology and Pathobiology (Arias, I. et al., eds), pp. 1059-1084, Raven Press
    • (1994) The Liver: Biology and Pathobiology , pp. 1059-1084
    • Fausto, N.1    Webber, E.2
  • 2
    • 0030091642 scopus 로고    scopus 로고
    • Hepatocyte proliferation induced by a single dose of a peroxisome proliferator
    • 2 Ohmura, T. et al. (1996) Hepatocyte proliferation induced by a single dose of a peroxisome proliferator, Am. J. Pathol. 148, 815-824
    • (1996) Am. J. Pathol. , vol.148 , pp. 815-824
    • Ohmura, T.1
  • 3
    • 0001896660 scopus 로고
    • Liver stem-cells
    • (Arias, L. et al., eds), Raven Press
    • 3 Fausto, N. (1994) Liver stem-cells, in The Liver: Biology and Pathobiology (Arias, L. et al., eds), pp. 1501-1518, Raven Press
    • (1994) The Liver: Biology and Pathobiology , pp. 1501-1518
    • Fausto, N.1
  • 4
    • 0002500444 scopus 로고
    • The role of bipotential progenitor cells in liver ontogenesis and neoplasia
    • (Sirica, A.E., ed.), CRC Press
    • 4 Marceau, N. et al. (1992) The role of bipotential progenitor cells in liver ontogenesis and neoplasia, in The Role of Cell Types in Hepatocarcinogenesis (Sirica, A.E., ed.), pp. 121-149, CRC Press
    • (1992) The Role of Cell Types in Hepatocarcinogenesis , pp. 121-149
    • Marceau, N.1
  • 5
    • 0028353410 scopus 로고
    • Replacement of diseased mouse liver by hepatic cell transplantation
    • 5 Rhim, J.A. et al. (1994) Replacement of diseased mouse liver by hepatic cell transplantation, Science 263, 1149-1152
    • (1994) Science , vol.263 , pp. 1149-1152
    • Rhim, J.A.1
  • 6
    • 0029557319 scopus 로고
    • Role of growth factors and cytokines in hepatic regeneration
    • 6 Fausto, N., Laird, A.D. and Webber, E.M. (1995) Role of growth factors and cytokines in hepatic regeneration, FASEB J. 9, 1527-1536
    • (1995) FASEB J. , vol.9 , pp. 1527-1536
    • Fausto, N.1    Laird, A.D.2    Webber, E.M.3
  • 7
    • 0025122144 scopus 로고
    • Liver regeneration: Molecular mechanisms of growth control
    • 7 Michalopoulos, G.K. (1990) Liver regeneration: molecular mechanisms of growth control, FASEB J. 4, 176-187
    • (1990) FASEB J. , vol.4 , pp. 176-187
    • Michalopoulos, G.K.1
  • 8
    • 0028023372 scopus 로고
    • Overexpression of transforming growth factor α causes liver enlargement and increased hepatocyte proliferation in transgenic mice
    • 8 Webber, E.M. et al. (1994) Overexpression of transforming growth factor α causes liver enlargement and increased hepatocyte proliferation in transgenic mice, Am. J. Pathol. 145, 398-408
    • (1994) Am. J. Pathol. , vol.145 , pp. 398-408
    • Webber, E.M.1
  • 9
    • 0028213841 scopus 로고
    • Hepatocyte growth factor in transgenic mice: Effects on hepatocyte growth, liver regeneration and gene expression
    • 9 Shiota, G., Wang, T., Nakamura, T. and Schmidt, E. (1994) Hepatocyte growth factor in transgenic mice: effects on hepatocyte growth, liver regeneration and gene expression, Hepatology 19, 962-972
    • (1994) Hepatology , vol.19 , pp. 962-972
    • Shiota, G.1    Wang, T.2    Nakamura, T.3    Schmidt, E.4
  • 10
    • 0028959432 scopus 로고
    • Induction of liver growth in normal mice by infusion of hepatocyte growth factor/scatter factor
    • 10 Roos, F. et al. (1995) Induction of liver growth in normal mice by infusion of hepatocyte growth factor/scatter factor, Am. J. Physiol. 268, G380-G386
    • (1995) Am. J. Physiol. , vol.268
    • Roos, F.1
  • 11
    • 0028040336 scopus 로고
    • In vivo response of hepatocytes to growth factors requires an initial priming stimulus
    • 11 Webber, E.M., Godowski, P.J. and Fausto, N. (1994) In vivo response of hepatocytes to growth factors requires an initial priming stimulus, Hepatology 19, 489-497
    • (1994) Hepatology , vol.19 , pp. 489-497
    • Webber, E.M.1    Godowski, P.J.2    Fausto, N.3
  • 12
    • 0028238890 scopus 로고
    • Collagenase pretreatment and the mitogenic effects of hepatocyte growth factor and transforming growth factor α in adult rat liver
    • 12 Liu, M-L., Mars, W.M., Zarnegar, R. and Michalopoulos, G.K. (1994) Collagenase pretreatment and the mitogenic effects of hepatocyte growth factor and transforming growth factor α in adult rat liver, Hepatology 19, 1521-1527
    • (1994) Hepatology , vol.19 , pp. 1521-1527
    • Liu, M.-L.1    Mars, W.M.2    Zarnegar, R.3    Michalopoulos, G.K.4
  • 13
    • 0028914369 scopus 로고
    • Rapid DNA binding by nuclear factor κB in hepatocytes at the start of liver regeneration
    • 13 FitzGerald, M., Webber, E., Donovan, J. and Fausto, N. (1995) Rapid DNA binding by nuclear factor κB in hepatocytes at the start of liver regeneration, Cell Growth Differ. 6, 417-427
    • (1995) Cell Growth Differ. , vol.6 , pp. 417-427
    • Fitzgerald, M.1    Webber, E.2    Donovan, J.3    Fausto, N.4
  • 14
    • 0028097547 scopus 로고
    • Rapid activation of post-hepatectomy factor/nuclear factor κB in hepatocytes, a primary response in the regenerating liver
    • 14 Cressman, D.E., Greenbaum, L.E., Haber, B.A. and Taub, R. (1994) Rapid activation of post-hepatectomy factor/nuclear factor κB in hepatocytes, a primary response in the regenerating liver, J. Biol. Chem. 269, 30429-30435
    • (1994) J. Biol. Chem. , vol.269 , pp. 30429-30435
    • Cressman, D.E.1    Greenbaum, L.E.2    Haber, B.A.3    Taub, R.4
  • 15
    • 0028984775 scopus 로고
    • Activation of jun kinase is an early event in hepatic regeneration
    • 15 Westwick, J., Weitzel, C., Leffert, H. and Brenner, D. (1995) Activation of jun kinase is an early event in hepatic regeneration, J. Clin. Invest. 95, 803-810
    • (1995) J. Clin. Invest. , vol.95 , pp. 803-810
    • Westwick, J.1    Weitzel, C.2    Leffert, H.3    Brenner, D.4
  • 16
    • 0030098001 scopus 로고    scopus 로고
    • Transcriptional control of liver regeneration
    • 16 Taub, R. (1996) Transcriptional control of liver regeneration, FASEB J. 10, 413-427
    • (1996) FASEB J. , vol.10 , pp. 413-427
    • Taub, R.1
  • 17
    • 0030077331 scopus 로고    scopus 로고
    • Regulation of signal transduction during liver regeneration
    • 17 Diehl, A.M. and Rai, R.M. (1996) Regulation of signal transduction during liver regeneration, FASEB J. 10, 215-227
    • (1996) FASEB J. , vol.10 , pp. 215-227
    • Diehl, A.M.1    Rai, R.M.2
  • 18
    • 0029049780 scopus 로고
    • Rapid activation of the stat3 transcription complex in liver regeneration
    • 18 Cressman, D.E., Diamond, R.H. and Taub, R. (1995) Rapid activation of the Stat3 transcription complex in liver regeneration, Hepatology 21, 1443-1449
    • (1995) Hepatology , vol.21 , pp. 1443-1449
    • Cressman, D.E.1    Diamond, R.H.2    Taub, R.3
  • 19
    • 0026801421 scopus 로고
    • Antibodies to tumor necrosis factor α inhibit liver regeneration after partial hepatectomy
    • 19 Akerman, P. et al. (1992) Antibodies to tumor necrosis factor α inhibit liver regeneration after partial hepatectomy, Am. J. Physiol. 263, G579-G585
    • (1992) Am. J. Physiol. , vol.263
    • Akerman, P.1
  • 20
    • 0027445066 scopus 로고
    • Cyclin and cyclin-dependent kinase 1 mRNA expression in models of regenerating liver and human liver diseases
    • 20 Albrecht, J.H., Hoffman, J.S., Kren, B.T. and Steer, C.J. (1993) Cyclin and cyclin-dependent kinase 1 mRNA expression in models of regenerating liver and human liver diseases, Am. J. Physiol. 265, G857-G864
    • (1993) Am. J. Physiol. , vol.265
    • Albrecht, J.H.1    Hoffman, J.S.2    Kren, B.T.3    Steer, C.J.4
  • 21
    • 0027242180 scopus 로고
    • c-jun is essential for normal mouse development and hepatogenesis
    • 21 Hilberg, F., Aguzzi, A., Howells, N. and Wagner, E. (1993) c-jun is essential for normal mouse development and hepatogenesis, Nature 365, 179-181
    • (1993) Nature , vol.365 , pp. 179-181
    • Hilberg, F.1    Aguzzi, A.2    Howells, N.3    Wagner, E.4
  • 22
    • 0028911690 scopus 로고
    • Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor
    • 22 Uehara, Y. et al. (1995) Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor, Nature 373, 702-705
    • (1995) Nature , vol.373 , pp. 702-705
    • Uehara, Y.1
  • 23
    • 0028899952 scopus 로고
    • Scatter factor/hepatocyte growth factor is essential for liver development
    • 23 Schmidt, C. et al. (1995) Scatter factor/hepatocyte growth factor is essential for liver development, Nature 373, 699-702
    • (1995) Nature , vol.373 , pp. 699-702
    • Schmidt, C.1
  • 24
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB
    • 24 Beg, A.A. et al. (1995) Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB, Nature 376, 167-170
    • (1995) Nature , vol.376 , pp. 167-170
    • Beg, A.A.1
  • 25
    • 0029846756 scopus 로고    scopus 로고
    • Liver Failure and defective hepatocyte regeneration in interleukin-6-deficient mice
    • 25 Cressman, D.E. et al. (1996) Liver Failure and defective hepatocyte regeneration in interleukin-6-deficient mice, Science 74, 1379-1383
    • (1996) Science , vol.74 , pp. 1379-1383
    • Cressman, D.E.1
  • 26
    • 4244079263 scopus 로고    scopus 로고
    • Initiation of liver growth by tumor necrosis factor: Deficient liver regeneration in mice lacking type ITNF receptor
    • in press
    • 26 Yamada, Y., Kirilova, I., Peschon, J.J. and Fausto, N. Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type ITNF receptor, Proc. Natl. Acad. Sci. U. S. A. (in press)
    • Proc. Natl. Acad. Sci. U. S. A.
    • Yamada, Y.1    Kirilova, I.2    Peschon, J.J.3    Fausto, N.4
  • 27
    • 0028342913 scopus 로고
    • Regulation of the transcription factors NF-κB and AP-1 by redox changes
    • 27 Meyer, M., Pahl, H.L. and Baeurle, P.A. (1994) Regulation of the transcription factors NF-κB and AP-1 by redox changes, Chemico-Biological Interactions 91, 91-100
    • (1994) Chemico-biological Interactions , vol.91 , pp. 91-100
    • Meyer, M.1    Pahl, H.L.2    Baeurle, P.A.3
  • 28
    • 0026501424 scopus 로고
    • Hepatocyte transplantation: Back to the future
    • 28 Gupta, S. and Chowdhury, J.R. (1992) Hepatocyte transplantation: back to the future, Hepatology 15, 156-160
    • (1992) Hepatology , vol.15 , pp. 156-160
    • Gupta, S.1    Chowdhury, J.R.2
  • 29
    • 0029113869 scopus 로고
    • Long-term hepatic adenovirus-mediated gene expression in mice following CTLA41g administration
    • 29 Kay, M.A. et al. (1995) Long-term hepatic adenovirus-mediated gene expression in mice following CTLA41g administration, Nat. Genet. 11, 191-197
    • (1995) Nat. Genet. , vol.11 , pp. 191-197
    • Kay, M.A.1
  • 30
    • 0029391177 scopus 로고
    • Beneficial effect of s-adenosylmethionine during both cold storage and cryopreservation of isolated hepatocytes
    • 30 Vara, E. et al. (1995) Beneficial effect of S-adenosylmethionine during both cold storage and cryopreservation of isolated hepatocytes, Cryobiology 32, 422-427
    • (1995) Cryobiology , vol.32 , pp. 422-427
    • Vara, E.1
  • 31
    • 0026031297 scopus 로고
    • Mouse hepatocytes migrate to liver parenchyma and function indefinitely after splenic transplantation
    • 31 Parker Ponder, K. et al. (1991) Mouse hepatocytes migrate to liver parenchyma and function indefinitely after splenic transplantation, Proc. Natl. Acad. Sci. U. S. A. 88, 1217-1221
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 1217-1221
    • Parker Ponder, K.1
  • 32
    • 0025912865 scopus 로고
    • Permanent engraftment and function of hepatocytes delivered to the liver: Implications for gene therapy and liver repopulation
    • 32 Gupta, S. et al. (1991) Permanent engraftment and function of hepatocytes delivered to the liver: implications for gene therapy and liver repopulation. Hepatology 14, 144-149
    • (1991) Hepatology , vol.14 , pp. 144-149
    • Gupta, S.1
  • 33
    • 0028168779 scopus 로고
    • Hepatocytes exhibit superior transgene expression after transplantation into liver and spleen compared with peritoneal cavity or dorsal fat pad: Implications for hepatic gene therapy
    • 33 Gupta, S. et al. (1994) Hepatocytes exhibit superior transgene expression after transplantation into liver and spleen compared with peritoneal cavity or dorsal fat pad: implications for hepatic gene therapy, Hum. Gene Ther. 5, 959-967
    • (1994) Hum. Gene Ther. , vol.5 , pp. 959-967
    • Gupta, S.1
  • 34
    • 0028104258 scopus 로고
    • Human fetal hepatocyte transplantation in patients with fulminant hepatic failure
    • 34 Habibullah, C-M., Syed, I-H., Qamar, A. and Tahar-Uz, Z. (1994) Human fetal hepatocyte transplantation in patients with fulminant hepatic failure, Transplantation 58, 951-952
    • (1994) Transplantation , vol.58 , pp. 951-952
    • Habibullah, C.-M.1    Syed, I.-H.2    Qamar, A.3    Tahar-Uz, Z.4
  • 35
    • 0027099789 scopus 로고
    • Hepatocyte transplantation in man
    • 35 Mito, M., Kusano, M. and Kawaura, Y. (1992) Hepatocyte transplantation in man, Transplant. Proc. 24, 3052-3053
    • (1992) Transplant. Proc. , vol.24 , pp. 3052-3053
    • Mito, M.1    Kusano, M.2    Kawaura, Y.3
  • 36
    • 0026890750 scopus 로고
    • A study of hepatocellular transplantation
    • 36 Kusano, M. and Mito, M. (1992) A study of hepatocellular transplantation, Nippon Rinsho 50, 1679-1688
    • (1992) Nippon Rinsho , vol.50 , pp. 1679-1688
    • Kusano, M.1    Mito, M.2
  • 37
    • 0028200645 scopus 로고
    • Proliferative response of hepatocytes transplanted into spleen or solid support
    • 37 Borel Rinkes, I.H. et al. (1994) Proliferative response of hepatocytes transplanted into spleen or solid support, J. Surg. Res. 56, 417-423
    • (1994) J. Surg. Res. , vol.56 , pp. 417-423
    • Borel Rinkes, I.H.1
  • 38
    • 0025781894 scopus 로고
    • Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene
    • 38 Sandgren, E.P. et al. (1991) Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene, Cell 66, 245-256
    • (1991) Cell , vol.66 , pp. 245-256
    • Sandgren, E.P.1
  • 39
    • 0028146998 scopus 로고
    • Self-induced correction of the genetic defect in tyrosinemia type 1
    • 39 Kvittingen, E.A. et al. (1993) Self-induced correction of the genetic defect in tyrosinemia type 1, J. Clin. Invest. 94, 1657-1661
    • (1993) J. Clin. Invest. , vol.94 , pp. 1657-1661
    • Kvittingen, E.A.1
  • 40
    • 0029875835 scopus 로고    scopus 로고
    • Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinemia type 1
    • 40 Overturf, K. et al. (1996) Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinemia type 1, Nat. Genet. 12, 266-273
    • (1996) Nat. Genet. , vol.12 , pp. 266-273
    • Overturf, K.1
  • 41
    • 0028283407 scopus 로고
    • Gene therapy for metabolic disorders
    • 41 Kay, M.A. and Woo, S.L. (1994) Gene therapy for metabolic disorders, Trends Genet. 10, 253-257
    • (1994) Trends Genet. , vol.10 , pp. 253-257
    • Kay, M.A.1    Woo, S.L.2
  • 42
    • 0026355641 scopus 로고
    • Long-term improvement of hypercholesterolemia after ex vivo gene therapy in LDLR-deficient rabbits
    • 42 Chowdhury, J.R. et al. (1991) Long-term improvement of hypercholesterolemia after ex vivo gene therapy in LDLR-deficient rabbits, Science 254, 1802-1805
    • (1991) Science , vol.254 , pp. 1802-1805
    • Chowdhury, J.R.1
  • 43
    • 0026586140 scopus 로고
    • 1-antitrypsin in dogs after autologous transplantation of retroviral transduced hepatocytes
    • 1-antitrypsin in dogs after autologous transplantation of retroviral transduced hepatocytes, Proc. Natl. Acad. Sci. U. S. A. 89, 89-93
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 89-93
    • Kay, M.A.1
  • 44
    • 0028793489 scopus 로고
    • A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia
    • 44 Grossman, M. et al. (1995) A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia. Nat. Med. 1, 1148-1154
    • (1995) Nat. Med. , vol.1 , pp. 1148-1154
    • Grossman, M.1
  • 45
    • 0028158811 scopus 로고
    • Liver-directed gene therapy: Quantitative evaluation of promoter elements by using in vivo retroviral transduction
    • 45 Rettinger, S.D. et al. (1994) Liver-directed gene therapy: quantitative evaluation of promoter elements by using in vivo retroviral transduction, Proc. Natl. Acad. Sci. U. S. A. 91, 1460-1464
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 1460-1464
    • Rettinger, S.D.1
  • 46
    • 0029088057 scopus 로고
    • A modified urokinase plasminogen activator induces liver regeneration without bleeding
    • 46 Lieber, A. et al. (1995) A modified urokinase plasminogen activator induces liver regeneration without bleeding, Hum. Gene Ther. 6, 1029-1037
    • (1995) Hum. Gene Ther. , vol.6 , pp. 1029-1037
    • Lieber, A.1
  • 47
    • 0029010354 scopus 로고
    • Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo
    • 47 Lieber, A. et al. (1995) Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo, Proc. Natl. Acad. Sci. U. S. A. 92, 6210-6214
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 6210-6214
    • Lieber, A.1
  • 48
    • 0028949815 scopus 로고
    • Early clinical experience with a hybrid bioartificial liver
    • 48 Demetriou, A.A. et al. (1995) Early clinical experience with a hybrid bioartificial liver, Scand. J. Gastroenterol. 208, 111-117
    • (1995) Scand. J. Gastroenterol. , vol.208 , pp. 111-117
    • Demetriou, A.A.1
  • 49
    • 0027156124 scopus 로고
    • Improved liver function following treatment with an extracorporeal liver assist device
    • 49 Sussman, N.L. and Kelly, J.H. (1993) Improved liver function following treatment with an extracorporeal liver assist device, Artif. Organs 17, 27-30
    • (1993) Artif. Organs , vol.17 , pp. 27-30
    • Sussman, N.L.1    Kelly, J.H.2


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