Affinity characterization of monoclonal and recombinant antibodies for multianalyte detection with an optical transducer

Sensors and Actuators, B: Chemical

Volumn 39, Issue 1-3, 1997, Pages 432-437

  Piehler, Jacob ^a   Brecht, Andreas ^a   Giersch, Thomas ^b   Kramer, Karl ^b   Hock, Bertold ^b   Gauglitz, Günter ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Antibody array; Immunoassay; Immunoprobe; Pattern recognition; s Triazines

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; CALCULATIONS; IMMUNOSENSORS; MONOCLONAL ANTIBODIES; TRANSDUCERS;

IMMUNOASSAY; IMMUNOPROBE; OPTICAL TRANSDUCERS;

OPTICAL SENSORS;

EID: 0031084093     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4005(96)02118-1     Document Type: Article

References (23)

1. Ch.P. Price and D.J. Newman (eds.), Principles and Practice of Immunoassay, Stockton Press, New York, 1991.
2. F.F. Bier and R.D. Schmid, Real time analysis of competitive binding using grating coupler immunosensor for pesticide detection, Biosensors Bioelectron., 9 (1994) 125-130.
3. M. Minnuni and M. Mascini, Detection of pesticide in drinking water using real-time bio-specific interaction analysis (BIA), Anal. Lett., 26 (1993) 1441-1460.
4. A. Brecht, J. Piehler, G. Lang and G. Gauglitz, A direct optical immunosensor for atrazine detection, Anal. Chim. Acta, 311 (1995) 289-299.
5. G. Lang, A. Brecht and G. Gauglitz, Characterisation and optimisation of an immunoprobe for triazines, Fresenius' Z. Anal. Chem., 354 (1996) 857-860.
6. C. Mouvet, L. Almaric, S. Broussard, G. Lang, G. Brecht and G. Gauglitz, Reflectometric interference spectroscopy for the determination of atrazine in natural water samples, Environmental Sci. Technol., in press (1996).
7. M.W. Steward and A.M. Lew, The importance of antibody affinity in the performance of immunoassays for antibody, J. Immunol. Methods, 78 (1985) 173-190.
8. T. Giersch, K. Kramer and B. Hock, Optimisation of a monoclonal antibody-based immunoassay for the detection of terbuthylazine, Sci. Total Environment, 132 (1993) 435-448.
9. M.T. Muldoon, G.F. Fries and J.O. Nelson, Evaluation of ELISA for the multianalyte analysis of s-triazines in pesticide waste and rinsate, J. Agricult. Food. Chem., 41 (1993) 322-328.
10. P.Y.K. Cheung, L.M. Kauvar, A.E. Enquist-Goldstein, and S.M. Ambler, Harnessing immunochemical cross-reactivity: use of pattern recognition to classify molecular analogs, Anal. Chim. Acta, 282 (1993) 181-192.
11. A.E. Karu, T.H. Lin, L. Breiman, M.T. Muldoon and J. Hsu, Use of multivariate statistical methods to identify immunochemical cross-reactants, Food Agricult. Immunol., 6 (1994) 371-384.
12. M. Wortberg, S.B. Kreissig, G. Jones, D.M. Rocke and B.D. Hammock, An immunoarray for the simultaneous determination of multiple triazine herbicides, Anal. Chim. Acta, 304 (1995) 339-352.
13. G. Jones, M. Wortberg, S.B. Kreissig, D.S. Bunch, S.J. Gee, B.D. Hammock and D.M. Rocke, Extension of the four parameter logistic model for ELISA to multianalyte analysis, J. Immunol. Meth., 177 (1994) 1-7.
14. J. Piehler, A. Brecht, K. Kramer, B. Hock and G. Gauglitz, Multi-analyte determination with an optical multi-antibody detection system, Proc. SPIE, Vol. 2504, Environmental Monitoring and Hazardous Waste Site Remediation, 1995, pp. 185-193.
15. J. Piehler, A. Brecht, Th. Giersch, B. Hock and G. Gauglitz, Assessment of affinity constants by rapid solid phase detection of equilibrium binding in a flow system, J. Immunol. Methods, in press.
16. J. Piehler, A. Brecht and G. Gauglitz, Surface modification for direct immunoprobes, Biosensors Bioelectron., 11 (1996) 579-590.
17. T. Giersch and B. Hock, Production of monoclonal antibodies for the determination of s-triazines with enzyme immunoassay, FoodAgricult. Immunol., 2 (1990) 85-97.
18. T. Giersch, A new monoclonal antibody for sensitive detection of atrazine with immunoassay in microtiter plate and dipstick format, J. Agricult. Food Chem., 41 (1993) 1006-1011.
19. K. Kramer, T. Giersch and B. Hock, Magnetic bead selection of hybridomas producing pesticide antibodies, Food Agricult. Immunol., 6 (1994) 5-16.
20. K. Kramer and B. Hock, Recombinant single-chain antibodies against s-triazines, Food Agricult. Immunol., 8 (1996) 97-109.
21. G. Gauglitz, A. Brecht, G. Kraus and W. Nahm, Chemical and biochemical sensors based on interferometry at thin (multi-)layers, Sensors and Actuators B, 11 (1993) 21-27.
22. A. Brecht and G. Gauglitz, Interferometric immunoassay in a FIA-system: a sensitive and rapid approach in label-free immunosensing, Biosensors Bioelectron., 8 (1993) 387-392.
23. J. Piehler, A. Brecht and G. Gauglitz, Affinity detection of low molecular weight analytes, Anal. Chem., 68 (1996) 139-143.