The effects of monophasic and triphasic oral contraceptives on ovarian function and endometrial thickness

European Journal of Contraception and Reproductive Health Care

Volumn 2, Issue 1, 1997, Pages 39-51

  Rabe, T ^a   Nitsche, D C ^a   Runnebaum, B ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Endometrium; Estradiol; Follicular cysts; Oral contraceptives; Ovarian inhibition; Progesterone; Ultrasonography

Indexed keywords

DESOGESTREL; DRUG DERIVATIVE; ESTRADIOL; ETHINYLESTRADIOL; ETHINYLESTRADIOL PLUS GESTODENE; ETHINYLESTRADIOL PLUS NORGESTIMATE; ETHINYLESTRADIOL PLUS NORGESTREL; ORAL CONTRACEPTIVE AGENT; PREGNANE DERIVATIVE; PROGESTERONE;

ADOLESCENT; ADULT; ARTICLE; BLOOD; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DRUG EFFECT; ENDOMETRIUM; FEMALE; HISTOLOGY; HUMAN; MIDDLE AGED; OVARY; PHYSIOLOGY;

ADOLESCENT; ADULT; CONTRACEPTIVES, ORAL, COMBINED; CONTRACEPTIVES, ORAL, SYNTHETIC; CROSS-SECTIONAL STUDIES; DESOGESTREL; ENDOMETRIUM; ESTRADIOL; ETHINYL ESTRADIOL; ETHINYL ESTRADIOL-NORGESTREL COMBINATION; FEMALE; HUMANS; MIDDLE AGED; NORPREGNENES; OVARY; PROGESTERONE;

EID: 0031083273     PISSN: 13625187     EISSN: None     Source Type: Journal    
DOI: 10.1080/13625189709049933     Document Type: Article

References (34)

1. Guillebaud J. The forgotten pill - and the paramount importance of the pill-free week. Br J Fam Plann 1987; 12 (suppl 4): 35-43
2. Korver T, Goorissen E, Guillebaud J. The combined oral contraceptive pill: what advice should we give when tablets are missed? Br J Obstet Gynaecol 1995; 102; 601-7
3. Runnebaum B, Rabe T, eds. Gynäkologische Endokrinologie, vol. 1. Berlin: Springer Verlag, 1994; 33-8, 67-70, 86-9, 389-404, 430-2, 451-2
4. Gips H, Runnebuam B. Kontrazeption bei prämenopausalen Frauen: Wie Sicherheit, Blutungen und Osteoporose-Prävention unter einen Hut zu bringen sind. Cyn News 1994; 1
5. Knörr K, Knörr-Gärtner H, Beller FK, Lauritzen C. Geburtshilfe und Gynäkologie Physiologie und Pathologie der Reproduktion, 3rd edn. Berlin: SpringerVerlag 1989; 575
6. Merz E, ed. Vaginalsonographie. Stuttgart: Ferdinand Enke Verlag, 1992; 25-35, 36-48
7. Bald R, Hackelöer B. Ultraschalldarstellung verschiedener Endometriumformen. In Otto RC, Jann FX, eds. Ultraschalldiagnostik 82. Stuttgart:Thieme, 1983; 187-92
8. Degenhardt F. Atlas der vaginale Ultraschalldiagnostik. Stuttgart: Wissenschaftliche Verlagsgesellschaft, 1988; 40-3
9. van derVange N. Ovarian activity during low dose oral contraceptives. In Chamberlain G, ed. Contemporary Obstetrics and Gynaecology. London: Butterworths, 1988; 315-26
10. Hamilton CJCM, Hoogland HJ. Longitudinal ultrasonographic study of the ovarian suppressive activity of a low-dose triphasic oral contraceptive during correct and incorrect pill intake. Am J Obstet Gynecol 1989; 161: 1559-62
11. Tayob Y, Robinson G, Adams J, et al. Ultrasound appearance of the ovaries during the pill-free interval. Br J Fam Plann 1990; 16: 94-6
12. Shaw G, Killick S, Elstein M. Assessment of ovarian activity in a gestodene containing triphasic oral contraceptive. Br J Fam Plann 1992; 18: 76-8
13. Fitzgerald C, Feichtinger W, Spona J, et al. A comparison of the effects of two monophasic low dose oral contraceptives on the inhibition of ovulation. Adv Contracept 1994; 10: 5-18
14. Killick S, Eyong E, Elstein M. Ovarian follicular development in oral contraceptive cycles. Fertil Steril 1987; 48: 409-13
15. Killick SR. Ovarian follicles during oral contraceptive cycles: their potential for ovulation. Fertil Steril 1989; 52: 580-2
16. Grimes DA, Godwin AJ, Rubin A, et al. Ovulation and follicular development associated with three low-dose oral contraceptives: a randomized controlled trial. Obstet Gynecol 1994; 83: 29-34
17. Mall-Haefeli M, Werner-Zodrow I, Huber PR. Klinische Erfahrungen mit Mercilon und Marvelon unter besonderer Berücksichtigung der Ovar-Funktion. Geburtshilfe Frauenheilkd 1991; 51: 34-8
18. Taylor DR, Anthony FW, Dennis KJ. Suppression of ovarian function by Microgynon 30 in day 1 and day 5 'starters'. Contraception 1986; 33: 463-71
19. Killick SR, Bancroft K, Oelbaum S, et al. Extending the duration of the pill-free interval during combined oral contraception. Adv Contracept 1990; 6: 33-40
20. Landgren BM, Csemiczky G. The effect on follicular growth and luteal function of 'missing the pill'. Contraception 1991; 43: 149-59
21. Hedon B, Cristol P, Plauchut A, et al. Ovarian consequences of the transient interruption of combined oral contraceptives. Int J Fertil 1992; 37: 270-6
22. Kuhnz W, Fritzemeier KH, Hegele-Hartung C, et al. Comparative progestational activity of norgestimate, levonorgestrel-oxime and levonorgestrel in the rat and binding of these compounds to the progesterone receptor. Contraception 1995; 51: 131-9
23. Porcu E, Venturoli S, Dal Prato L, et al. Frequency and treatment of ovarian cysts in adolescence. Arch Gynecol Obstet 1994; 255: 69-72
24. Rabe T. Gynäkologie und Geburtshilfe, 1st edn. Weinheim: Medizin VCH, 1990; 235-6
25. Denis C. Oral contraception: disadvantages of estrogen reduction. Contracept Fertil Sex 1993; 21: 481-8
26. Corson SL. Contraceptive efficacy of a monophasic oral contraceptive containing desogestrel. Am J Obstet Gynecol 1993; 168: 1017-20
27. Mall-Haefeli M, Werner-Zodrow PR, Edelmann A. Oral contraception and ovarian function. In Runnebaum B, Rabe T, Kiesel C, eds. Female Contraception, 1st edn. Berlin: Springer Verlag, 1988; 97-105
28. Egarter C, Putz M, Strohmer H, et al. Ovarian function during low-dose oral contraceptive use. Contraception 1995; 51: 329-33
29. Sterzik K, Grab D, Rosenbusch B, et al. Zur Rezeptivität des Endometriums: Vergleich sonographischer und histologischer Befunde nach hormonelle Stimulation. Geburtshilfe Frauenheilkd 1991; 51: 554-8
30. Fleischer AC, Kalemeris GC, Machin JE, et al. Sonographic depiction of normal and abnormal endometrium with pathologic correlation. J Ultrasound Med 1986; 86: 445-52
31. Taubert HD, Kuhl H. Kontrazeption mit Hormonen, 2nd edn. Stuttgart: Thieme, 1995; 132-5, 251-2
32. Dallenbach-Hellweg G, Fenzel J. Die Abhängigkeit morphologischerVeränderungen an Portio, Cervix und Endometrium von Dosierung oder Potenz synthetischer Gestagene. Gebursthilfe Frauenheilkd 1985; 45: 238-43
33. Farkas M. Comparative evaluation of the effect of mono-, bi- and three-phase oral contraceptive tablets on the endometrium. Acta Pharm Hung 1992; 62: 284-94
34. Eyong E, Buchi K, Elstein M. Effects of 180 mg and 250 mg norgestimate on pituitary/ovarian function and cervical mucus. Fertil Steril 1988; 50: 756-60