New nepenthone and thevinone derivatives

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 2, 1997, Pages 369-382

  Marton, János ^a   Simon, Csaba ^a   Hosztafi, Sándor ^a   Szabó, Zoltán ^a   Márki, Árpád ^b   Borsodi, Anna ^b   Makleit, Sándor ^c  

^a Alkaloida Chemical Company Ltd   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Opioid receptor specificity; 6,14 Ethenomorphinans; Nepenthone; Thevinone

Indexed keywords

BUPRENORPHINE; DELTA OPIATE RECEPTOR; DIPRENORPHINE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ETHYLKETAZOCINE; ETORPHINE; MORPHINAN DERIVATIVE; MU OPIATE RECEPTOR;

ALKYLATION; ANIMAL TISSUE; ARTICLE; BRAIN; CHIRALITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; STEREOCHEMISTRY;

ANIMALS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MORPHINANS; RATS; STEREOISOMERISM;

ANIMALIA;

EID: 0031081617     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(96)00257-X     Document Type: Article

References (16)

1. 1. Wang, D.-X.; Lu, X.-Q.; Qin, B.-Y. J. Pharm. Pharmacol. 1995, 47, 669.
2. 2. Bentley, K. W.; Hardy, D. G. J. Am. Chem. Soc. 1967, 69, 3281.
3. 3. Bentley, K. W.; Hardy, D. G.; Meek, B. J. Am. Chem. Soc. 1967, 89, 3273.
4. 4. Fulmor, W.; Lancaster, J. E.; Morton, G. O.; Brown, J. J.; Howell, C. F.; Nora, C. T.; Hardy, R. A. J. J. Am. Chem. Soc. 1967, 89, 3322.
5. 5. Bentley, K. W.; Ball, J. C. J. Org. Chem. 1958, 23, 1720.
6. 6. Marton, J.; Szabó, Z.; Simon, C.; Hosztafi, S.; Makleit, S. Liebigs Ann. Chem. 1996, 1653.
7. 7. Marton, J.; Szabó, Z.; Hosztafi, S. Liebigs Ann. Chem. 1993, 915.
8. 8. Marton, J.; Hosztafi, S.; Berényi, S.; Simon, C.; Makleit, S. Monatsh. Chem. 1994, 125, 1229.
9. 9. Lewis, J. W.; Readhead, M. J. Tetrahedron 1968, 24, 1829.
10. 10. Valhari, M. U.; Rahman, A. U.; Memon, M. U.; Nachnani, F. C.; Khan, M. Y. Sci. Int. (Lahore) 1992, 4, 53.
11. 11. Pasternak, G. W.; Wilson, H. A., Snyder, S. H. Mol. Pharmacol. 1975, 11, 340.
12. 12. Bradford, M.-Anal. Biochem. 1976, 72, 248.
13. 13. Búzás, B.; Tóth, G.; Cavagnero, S.; Hruby, V. J.; Borsodi, A. Life Sci. 1992, 50, PL71.
14. 14. Handa, B. K.; Lane, A. C.; Lord. J. A. H.; Morgan, B. A.; Rance, M. J.; Smith, C. F. C. Eur. J. Pharm. 1981, 70, 531.
15. 15. Munson, P. J.; Rodbard, D. Anal. Biochem. 1980, 107. 220.
16. 16. Klein, P.; Nelson, W. L.; Yao, Y.-H.; Simon, E. J. J. Med. Chem. 1990, 33, 2286.