Characterization of ciguatoxins and ciguatoxin congeners present in ciguateric fish by gradient reverse-phase high-performance liquid chromatography/mass spectrometry

Toxicon

Volumn 35, Issue 2, 1997, Pages 159-168

  Lewis, Richard J ^a   Jones, Alun ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CIGUATOXIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG MIXTURE; DRUG PURIFICATION; FISH; INTOXICATION; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; VISCERA;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIGUATOXINS; EELS; FEMALE; MALE; MASS SPECTROMETRY; MICE;

ANGUILLIFORMES; ANIMALIA; LYCODONTIS;

EID: 0031081484     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(96)00132-8     Document Type: Article

References (12)

1. Gillespie, N. C., Lewis, R. J., Pearn, J., Bourke, A. T. C., Holmes, M. J., Bourke, J. B. and Shields, W. J. (1986) Ciguatera in Australia: occurrence, clinical features, pathophysiology and management. Med. J. Aust. 145, 584-590.
2. Holmes, M. J. and Lewis, R. J. (1992) Multiple gambiertoxins (ciguatoxin precursors) from an Australian strain of Gambierdiscus toxicus in culture. In: Recent Advances in Toxinology Research, Vol. 2, pp. 520-530 (Gapalakrishnakone, P. and Tan, C. K., Eds). Singapore: National University of Singapore.
3. Ijames, C. F., Dutky, R. C. and Fales, H. M. (1995) Iron carboxylate oxygen-centred-triangle complexes detected during electrospray use of organic acid modifiers with a comment on the Finnigan TSQ-700 electrospray inlet system. J. Am. Soc. Mass Spectr. 6, 1226-1231.
4. Kuhlmann, F. E., Apffel, A., Fischer, S. M., Goldberg, G. and Goodley, P. C. (1995) Signal enhancement for gradient reverse phase high-performance liquid chromatography - electrospray ionisation mass spectrometry analysis with trifluoroacetic and other strong acid modifiers by postcolumn addition of propionic acid and isopropanol. J. Am. Soc. Mass Spectr. 6, 1221-1225.
5. Lewis, R. J. and Holmes, M. J. (1993) Origin and transfer of toxins involved in ciguatera. Comp. Biochem. Physiol. 106C, 615-628.
6. Lewis, R. J. and Sellin, M. (1992) Multiple ciguatoxins in the flesh of fishes. Toxicon 30, 915-919.
7. Lewis, R. J. and Sellin, M. (1993) Recovery of ciguatoxin from fish flesh. Toxicon 31, 1333-1336.
8. Lewis, R. J., Sellin, M., Poli, M. A., Norton, R. S., MacLeod, J. K. and Shell, M. M. (1991) Purification and characterization of ciguatoxins from moray eel (Lycodontis javanicus, Muraenidae). Toxicon 29, 1115-1127.
9. Lewis, R. J., Holmes, M. J., Alewood, P. F. and Jones, A. (1994) Ionspray mass spectrometry of ciguatoxin-1, maitotoxin-2, and -3, and related marine polyether toxins. Nat. Toxins 2, 56-63.
10. Murata, M., Legrand, A. M., Ishibashi, Y., Fukui, M. and Yasumoto, T. (1990) Structures and configurations of ciguatoxin from moray eel Gymnothorax javanicus and its likely precursor from the dinoftagellate Gambierdiscus toxicus. J. Am. chem. Soc. 112, 4380-4386.
11. Pauillac, S., Bléchaut, J., Cruchet, P., Lotte, C. and Legrand, A.-M. (1995) Recent advances in detection of ciguatoxins in French Polynesia. In: Harmful Marine Algal Blooms, pp. 801-808 (Lassus, P., Arzul, G., Erad, E., Gentien, P. and Marcaillou, C., Eds). Lavoisier: Intercept.
12. Yasumoto, T., Satake, M., Fukui, M., Nagai, H., Murata, M. and Legrand, A.-M. (1993) A turning point in ciguatera study. In: Toxic Phytoplankton Blooms in the Sea, pp. 455-461 (Smayda, T. J. and Shimizu, Y., Eds). New York: Plenum Press.