A detailed lectin analysis of IgG glycosylation, demonstrating disease specific changes in terminal galactose and N-acetylglucosamine

Journal of Autoimmunity

Volumn 10, Issue 1, 1997, Pages 77-85

  Bond, Angela ^a   Alavi, Azita ^a   Axford, John S ^a   Bourke, Brian E ^b   Bruckner, Felix E ^b   Kerr, Michael A ^c   Maxwell, J Douglas ^a   Tweed, Karen J ^a   Weldon, Michael J ^a   Youinou, Pierre ^d   Hay, Frank C ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b ST GEORGE S HOSPITAL   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

Author keywords

ankylosing spondylitis; Crohn's disease; galactose; IgG glycosylation; infectious endocarditis; juvenile onset chronic arthritis; N acetylglucosamine; osteoarthritis; rheumatoid arthritis; Sjogren's syndrome; SLE; ulcerative colitis

Indexed keywords

GALACTOSE; IMMUNOGLOBULIN G; LECTIN; N ACETYLGLUCOSAMINE;

ADULT; AGED; ARTHRITIS; ARTICLE; CONTROLLED STUDY; CROHN DISEASE; GLYCOSYLATION; HUMAN; IMMUNOBLOTTING; MAJOR CLINICAL STUDY; OSTEOARTHRITIS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SJOEGREN SYNDROME;

EID: 0031081480     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.1996.0104     Document Type: Article

References (36)

1. Parekh R.B., Dwek R.A., Sutton R.A., Fernandes D.L., Leung A., Stanworth D., Rademacher T.W., Mizuochi T., Taniguchi T., Matsuta K., Takeuchi F., Nagano Y., Miyamoto T., Kobata A. Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG. Nature. 316:1985;452-457.
2. Parekh R.B., Ansell B.M., Isenberg D.A., Roitt I.M., Dwek R.A., Rademacher T.W. Galactosylation of IgG-associated oligosaccharides: reduction in patients with adult and juvenile onset rheumatoid arthritis and relation to disease activity. Lancet. i:1988;966-969.
3. Parekh R., Isenberg D., Rook G., Roitt I., Dwek R., Rademacher T. A comparative analysis of disease-associated changes in the galactosylation of serum IgG. J. Autoimmunity. 2:1989;101-114.
4. Axford J.S. Glycosylation and rheumatic disease: More than icing on the cake. J. Rheumatol. 21:1994;1791-1795.
5. Bond A., Cooke A., Hay F.C. Glycosylation of IgG, immune complexes and IgG subclasses in the MRL-lpr/lpr mouse model of rheumatoid arthritis. Eur. J. Immunol. 20:1990;2229-2233.
6. Bond A., Alavi A., Hay F.C., Axford J.S. Immunoglobulin G glycosylation changes occur in rheumatoid arthritis and primary Sjögren's syndrome but due to different mechanisms. Arthritis Rheum. 36:1993.
7. Bond A., Alavi A., Axford J.S., Youinou P., Hay F.C. The relationship between exposed galactose and N-acetylglucosamine residues on IgG in rheumatoid arthritis, juvenile chronic arthritis and Sjögren's syndrome. Clin. Exp. Immunol. 105:1996;99-103.
8. Arnett F.C., Edworthy S.M., Block D.A., McShane D.J., Fries J.F., Cooper M.S., Healy L.A., Kaplan S.R., Liang M.H., Luthra H.S., Medsger Jr T.A., Mitchell D.M., Neustadt D.H., Pinals R.S., Schaller J.G., Sharp J.T., Wilder R.L., Hunder G.G. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31:1988;315-324.
9. Tan E.M., Cohen A.S., Fries J.F., Masi A.T., McShane D.J., Rothfield N., Schaller J.G., Talal N., Winchester R.J. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25:1982;1271-1277.
10. Bennett P.H., Burch T.A. New York symposium on population studies in the rheumatic diseases: new diagnostic criteria. Bull. Rheum. Dis. 17:1967;453-458.
11. Lennard-Jones J.E. Classification of inflammatory bowel disease. Scand. J. Gastroenterol. Suppl. 170:1989;2-6.
12. Vitali C., Bombardieri S., Moutsopoulos H.M., Balestrieri G., Bencivelli W., Bernstein R.M., Bjerrum K.B., Braga S., Coll J., de Vita S., Drosos A.A., Ehrenfeld M., Hatron P.Y., Hay E.M., Isenberg D.A., Janin A., Kalden J.R., Kater L., Konttinen Y.T., Maddison P.J., Maini R.N., Manthorpe R., Meyer O., Ostuni P., Pennec Y., Prause J.U., Richards A., Sauvezie B., Schiödt M., Sciuto M., Scully C., Shoenfeld Y., Skopouli F.N., Smolen J.S., Snaith M.L., Tishler M., Todesco S., Valesini G., Venables P.J.W., Wattiaux M.J., Youinou P. Preliminary criteria for the classification of Sjögren's syndrome. Results of a prospective concerted action supported by the European community. Arthritis Rheum. 36:1993;340-347.
13. Truelove S., Witts L. Cortisone and corticotrophin in ulcerative colitis. BMJ. 1:1960;464-467.
14. Best W.R., Becktel J.M., Singleton J.W., Kerr Jr F. Development of a Crohn's disease activity index. National Co-operative Crohn's disease study. Gastroenterology. 70:1976;439-444.
15. Harvey R.F., Bradshaw J.M. A simple index of Crohn's disease activity. Lancet. i:1980.
16. Bond A., Jones M.G., Hay F.C. Human IgG preparations isolated by ion-exchange chromatography differ in their glycosylation profiles. J. Immunol. Methods. 166:1993;27-33.
17. Hudson, L. Hay, F.C. 1989, Single radial immuno-diffusion (SRID), Practical Immunology, 3rd edn, Blackwell Scientific Publications, Oxford.
18. Hardy, R.R. 1986, Purification and characterisation of monoclonal antibodies, Handbook of Experimental Immunology. Volume I, Immunochemistry, 4th edn, D.M. Weir, Blackwell Scientific, Oxford.
19. Sumar N., Bodman K.B., Rademacher T.W., Dwek R.A., Williams P., Parekh R.B., Edge J., Rook G., Isenberg D.A., Hay F.C., Roitt I.M. Analysis of glycosylation changes in IgG using lectins. J. Immunol. Methods. 131:1990;127-136.
20. Bland, M. 1995, Comparisons of means after analysis of variance, An introduction to medical statistics, 2nd edn, M. Bland, Oxford University Press, New York.
21. Gardner, M.J. Altman, D.G. 1989, Calculating confidence intervals for regression and correlation, Statistics with confidence, 1st edn, M.J. GardnerD.G. Altman, The Universities Press, London.
22. Tomana M., Schrohenloher R.E., Koopman W.J., Alarcón G.S., Paul W.A. Abnormal glycosylation of serum IgG from patients with chronic inflammatory diseases. Arthritis Rheum. 31:1988;333-338.
23. Kerr M.A., Wilton E., Naama J.K., Whaley K. Circulating immune complexes associated with decreased complement mediated inhibition of immune precipitation in sera from patients with bacterial endocarditis. Clin. Exp. Immunol. 63:1986;359-366.
24. Parekh R., Roitt I., Isenberg D., Dwek R., Rademacher T. Age-related galactosylation of the N-linked oligosaccharides of human serum IgG. J. Exp. Med. 167:1988;1731-1736.
25. Axford J.S., Sumar N., Alavi A., Isenberg D.A., Young A., Bodman K.B., Roitt I.M. Changes in normal glycosylation mechanisms in autoimmune rheumatic disease. J. Clin. Invest. 89:1992;1021-1031.
26. Hunt K., Bond A., Alavi A., Mrazek I., Sharrock C., Hay F.C., Axford J.S. In healthy individuals increased agalactosylated IgG is found in males and those with HLA DR 2 and 7 gene expression. Br. J. Rheum. 30:1991.
27. Zamze S.E., Ashford D.A., Wooten E.N., Rademacher T.W., Dwek R.A. Structural characterization of the asparagine-linked oligosaccharides fromTrypanosoma brucei. J. Biol. Chem. 266:1991;20244-20261.
28. Alavi A., Axford J.S. The glycosyltransferases. Isenberg D.A., Rademacher T.W. Abnormalities of IgG glycosylation and immunological disorders, 1st edn. 1996;John Wiley, Chichester.
29. Thompson S.J., Leader K.A., Lastra G.C., Elson C.J. The role of agalactosyl IgG in rodent models of autoimmune disease and in the pathogenesis of rheumatoid arthritis. Isenberg D.A., Rademacher T.W. Abnormalities of IgG glycosylation and immunological disorders, 1st edn. 1996;John Wiley, Chichester.
30. Wilson C., Ebringer A., Ahmadi K., Wrigglesworth J., Tiwana H., Fielder M., Binder A., Ettelaie C., Cunningham P., Joannou C., Bansal S. Shared amino acid sequences between major histocompatibility complex class II glycoproteins, type XI collagen and Proteus mirabilis in rheumatoid arthritis. Ann. Rheum. Dis. 54:1995;216-220.
31. Sanderson J.D., Moss M.T., Tizard M.L., Hermon-Taylor J. Mycobacterium paratuberculosis DNA in Crohn's disease tissue. Gut. 33:1992;890-896.
32. Ebringer A. Ankylosing spondylitis is caused by Klebsiella. Spondyloarth. 18:1992;105-121.
33. MacSween, R.N.M. Whaley, K. 1992, Cardiovascular system, Muir's textbook of pathology, 13th edn, R.N.M. MacSweenK. Whaley, Edward Arnold, London.
34. Shillitoe E.J., Daniels T.E., Whitcher J.P., Strand D.V., Talal N., Greenspan J.S. Antibody to cytomegalovirus in patients with Sjögren's syndrome as detected by enzyme linked immunosorbent assay. Arthritis Rheum. 25:1982;260-265.
35. Wolf H., Haus M., Wilmes E. Persistence of Epstein-Barr virus in the parotid gland. J. Virol. 51:1984;795-798.
36. Bond A., Kerr M.A., Hay F.C. Distinct oligosaccharide content of rheumatoid arthritis-derived immune complexes. Arthritis Rheum. 38:1995;744-749.