The human erythroid-specific transcription factor EKLF localizes to chromosome 19p13.12-p13.13

Genomics

Volumn 39, Issue 3, 1997, Pages 393-395

  Van Ree, Janine H ^a   Roskrow, Marie A ^a   Becher, Anna M ^a   McNall, Renée ^a   Valentine, Virginia A ^a   Jane, Stephen M ^c   Cunningham, John M ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROID KRUPPEL LIKE FACTOR; TRANSCRIPTION FACTOR;

ARTICLE; CHROMOSOME 19P; ERYTHROID CELL; ERYTHROPOIESIS; GENE LOCUS; GENE MAPPING; HUMAN; PRIORITY JOURNAL; TISSUE SPECIFICITY;

EID: 0031081372     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.4472     Document Type: Article

References (12)

1. ink4. Mol. Cell. Biol. 15: 2682-2688.
2. 2. Cunningham, J. M., and Jane, S. M. (1996). Hemoglobin switching and fetal hemoglobin reactivation. Semin. Hematol. 33: 1-7.
3. 3. Donze, D., Townes, T. M., and Bieker, J. J. (1995). Role of erythroid Krüppel-like factor in human γ-to β-globin gene switching. J. Biol. Chem. 270: 1955-1959.
4. 4. Feng, W. C., Southwood, C. M., and Bieker, J. J. (1994). Analyses of β-thalassemia mutant DNA interactions with erythroid Krüppel-like factor (EKLF), an erythroid cell-specific transcription factor. J. Biol. Chem. 269: 1493-1500.
5. 5. Kulozik, A. E., Bellan-Koch, A., Bail, S., Kohne, E., and Kleihauer, E. (1991). Thalassemia intermedia: Moderate reduction of beta globin gene transcriptional activity by a novel mutation of the proximal CACCC promoter element. Blood 77: 2054-2058.
6. 6. Miller, I. J., and Bieker, J. J. (1993). A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins. Mol. Cell. Biol. 13: 2776-2786.
7. 7. Mitelman, F. (1994). "Catalog of Chromosome Aberrations in Cancer," pp. 3076-3077, Wiley-Liss, New York.
8. 8. Nuez, B., Michalovich, D., Bygrave, A., Ploemacher, R., and Grosveld, F. (1995). Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene. Nature 375: 316-318.
9. 9. Orkin, S. H., Antonarakis, S. E., and Kazazian, H. H., Jr. (1984). Base substitution at position -88 in a beta-thalassemic globin gene. Further evidence for the role of distal promoter element ACACCC. J. Biol. Chem. 259: 8679-8681.
10. 10. Perkins, A. C., Gaensler, K. M. L., and Orkin, S. H. (1995). The transcription factor, EKLF, is required for completion of the developmental switch from human γ-to β-globin gene expression. Blood 86: 248a [Abstract].
11. 11. Perkins, A. C., Sharpe, A. H., and Orkin, S. H. (1995). Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF. Nature 375: 318-322.
12. 12. Stamatoyannopoulos, G., and Nienhuis, A. W. (1994). Hemoglobin switching. In "The Molecular Basis of Blood Diseases" (G. Stamatoyannopoulos, et al., Eds.), pp. 107-156, Saunders, Philadelphia.