Combined effects of sesamin with alpha-tocopherol or tocotrienols on lipid and immune indices in Brown-Norway rats

Nutrition Research

Volumn 17, Issue 2, 1997, Pages 339-350

  Gu, Jiong Yan ^a   Tsujita, Akira ^a   Wakizono, Yoko ^a   Yamada, Koji ^a   Sugano, Michihiro ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Immunoglobulin; Leukotriene; Lymphocyte; Sesamin; Tocopherol; Tocotrienol

Indexed keywords

ALPHA TOCOPHEROL; CD4 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; SESAMIN; THIOBARBITURIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; FAT INTAKE; FOOD COMPOSITION; IMMUNOREACTIVITY; LIPID METABOLISM; LYMPHOCYTE COUNT; MALE; MESENTERY LYMPH NODE; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE;

EID: 0031081326     PISSN: 02715317     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0271-5317(96)00263-1     Document Type: Article

References (28)

1. 1. Sugano M, and Akimoto K. Sesamin: a multifunctional gift from nature. J Chinese Nutr Sci 1993; 18:1-11.
2. 2. Namiki M. The chemistry and physiological functions of sesame. Food Reviews International 1995; 11:281-329.
3. 3. Nakabayashi A, Kitagawa Y, Suwa Y, Akimoto K, Asami S, Shimizu S, Hirose N, Sugano M, and Yamada H. α-Tocopherol enhances the hypocholesterolemic action of sesamin in rats. Internat J Vit Nutr Res 1995; 65:162-168.
4. 4. Qureshi AA, Burger WC, Peterson DM and Elson CE. The structure of an inhibitor of cholesterol biosynthesis isolated from barley. J Biol Chem 1986; 261:10544-10550.
5. 5. Pearce BC, Parker RA, Deason ME, Qureshi AA, and Wright JJ. Hypocholesterolemic activity of synthetic and natural tocotrienols. J Med Chem 1992; 35:3595-3606.
6. 6. Goh SH, Hew NF, Norhanom AW, and Yadav M. Inhibition of tumor promotion by various palm-oil tocotrienols. Int J Cancer 1994; 57:529-531.
7. 7. Hayes KC, Pronczuk A, and Liang JS, Differences in the plasma transport and tissue concentration of tocopherol and tocotrienol: observation in humans and hamsters. Proc Soc Exp Biol Med 1993; 202:353-359.
8. 8. Shimizu S, Akimoto K, Shinmen Y, Kawashima H, Sugano M, and Yamada Y. Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acid biosynthesis. Lipids 1991; 26:512-516.
9. 9. Gu JY, Nonaka M, Yamada K, Yoshimura K, Takasugi M, Ito Y, and Sugano M. Effects of sesamin and α-tocopherol on the production of chemical mediators and immunoglobulins in Brown-Norway rats. Biosci Biotech Biochem 1994; 58:1855-1858.
10. 10. Gu JY, Wakizono Y, Tsujita A, Lim BO, Nonaka M, Yamada K, and Sugano M. Effects of sesamin and α-tocopherol, individually or in combination, on the polyunsaturated fatty acid metabolism, chemical mediator production, and immunoglobulin levels in Sprague-Dawley rats. Biosci Biotech Biochem 1995; 59: 2198-2202.
11. 11. Atkinson HAC and Miller K. Assessment of the Brown Norway rat as a suitable model for the investigation of food allergy. Toxicology 1994; 91:281-288.
12. 12. American Institute of Nutrition. Report of the American Institute of Nutrition Ad Hoc committee on standards for nutritional studies. J Nutr 1977; 107:1340-1348.
13. 13. Lim BO, Yamada K, and Sugano M. Effects of bile acids and lectins on immunoglobulin production in rat mesenteric lymph node lymphocytes. In Vitro Cell Dev Biol 1994; 30: 407-413.
14. 14. Folch J, Lees M, and Sloane-stanley GH. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957; 226:497-509.
15. 15. Nagata Y, Imaizumi K, and Sugano M. Effects of soya-bean protein and casein on serum cholesterol levels in rats. Br J Nutr 1980; 44:113-121.
16. 16. Claude L and Xavier P. Thin-layer chromatography of human platelet phospholipids with fatty acid analysis. J Chromatogr 1987; 420:411-416.
17. 17. Ikeda I, Tamari Y, and Sugano M. Interrelated effects of dietary fiber and fat on lymphatic cholesterol and triglyceride absorption in rats. J Nutr 1989; 119:1383-1387.
18. 18. Yagi K. A simple fluorometric assay for lipoperoxide in blood plasma. Biochem Med 1976; 15:212-216.
19. 19. Moqbel R, Wakelin D, MacDonald AJ, King SJ, Grencis RK, and Kay AB. Release of leukotrienes during rapid expulsion of Trichinella spiralis from immune rats. Immunology 1987; 60:425-430.
20. 20. Duncan DB. Multiple range tests for correlated and heteroscedastic means. Biometrics 1957; 3:164-176.
21. 21. Sundram R, Khor H, Ong AS and Pathmanathan R. Effect of dietary palm oil on mammary carcinogenesis in female rats induced by 7,12-dimethylbenz(a) anthracene. Cancer Res 1989; 49:1447-1451.
22. 22. Komiyama K, Iizuka K, Yamaoka M, Watanabe H, Tsuchiya N, and Umezawa I. Studies on the biological activity of tocotrienols. Chem Pharm Bull 1989; 37:1369-1371.
23. 23. Sugano M and Imaizumi K. Effect of palm oil on lipid and lipoprotein metabolism and eicosanoid production in rats. Am J Cli Nutr 1991; 53 (suppl.): 1034S-1038S.
24. 24. Wahlqvist ML, Krivokuca-Bogetic Z, Lo CS, Hage B, Smith R, and Likito W. Differential serum responses of tocopherols and tocotrienols during vitamin supplementation in hypercholesterolemic individuals without change in coronary risk factors. Nutr Res 1992; 12:S181-S201.
25. 25. Howard HT, Rundell CA, Batsakis JG. Vitamin E and serum tipoproteins: a non-correlation. Am J Clin Pathol 1982; 77:243-244.
26. 26. Serbinova E, Kagan V, Han D, Packer L. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol. Free Radic Biol Med 1991; 10:263-275.
27. 27. Koba K, Abe K, Ikeda I, and Sugano M. Effects of α-tocopherol and tocotrienols on blood pressure and linoleic acid metabolism in the spontaneously hypertensive rat (SHR). Biosci Biotech Biochem 1992; 56:1420-1423.
28. 28. Yamashita K, Nohara Y, Katayama K, and Namiki M. Sesame seed lignans and gamma-tocopherol act synergistically to produce vitamin E activity in rats. J Nutr 1992; 122:2440-2446.