Mechanism of thrombin inhibition by heparin cofactor II in the presence of dermatan sulphates, native or oversulphated, and a heparin-like dextran derivative

Biomaterials

Volumn 18, Issue 4, 1997, Pages 359-366

  Maaroufi, Raoui M ^a   Jozefowicz, Marcel ^b   Tapon Bretaudière, Jacqueline ^a   Jozefonvicz, Jacqueline ^b   Fischer, Anne Marie ^a  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b UNIVERSITÉ PARIS 13   (France)

Author keywords

Dermatan sulphate; Dextran; Heparin; Heparin cofactor II; Thrombin

Indexed keywords

CALCULATIONS; CHEMICAL ANALYSIS; DERIVATIVES; DISSOCIATION; ENZYME INHIBITION; MATHEMATICAL MODELS; POLYSACCHARIDES; REACTION KINETICS;

DERMATAN SULPHATES; HEPARIN COFACTOR; HEPARIN LIKE DEXTRAN DERIVATIVE; PROTEASE; THROMBIN INHIBITION;

DRUG INTERACTIONS;

ANTICOAGULANT AGENT; DERMATAN SULFATE; DEXTRAN DERIVATIVE; DISACCHARIDE; FIBRINOGEN; HEPARIN COFACTOR II; POLYSACCHARIDE; PROTEINASE; THROMBIN; THROMBIN INHIBITOR;

ARTICLE; BINDING AFFINITY; CHEMICAL REACTION KINETICS; COMPLEX FORMATION; DISSOCIATION CONSTANT; MODEL; PRIORITY JOURNAL;

EID: 0031081212     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/0142-9612(95)00355-X     Document Type: Article

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