Mutants in the CtpA copper transporting P-type ATPase reduce virulence of Listeria monocytogenes

Microbial Pathogenesis

Volumn 22, Issue 2, 1997, Pages 67-78

  Francis, Matthew S ^a   Thomas, Connor J ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

copper transport; Listeria monocytogenes; murine model of infection; P type ATPase; pathogenesis

Indexed keywords

ADENOSINE TRIPHOSPHATASE;

ANIMAL MODEL; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CONTROLLED STUDY; COPPER METABOLISM; IN VITRO STUDY; LISTERIA MONOCYTOGENES; LISTERIOSIS; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0031080061     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1006/mpat.1996.0092     Document Type: Article

References (48)

1. 1 Nieman RE, Lorber B. Listeriosis in adults: A changing pattern. Report of eight cases and review of the literature, 1968-1978. Rev Infect Dis 1980; 2: 207-27.
2. 2 Bille J, Doyle MP. Listeria and Erysipelothrix. In: Lennette EH, Balows A, Hausler WJ Jr, Shadomy HJ, eds. Manual of Clinical Microbiology. Washington DC: American Society for Microbiology, 1991: 287-95.
3. 3 Francis MS, Thomas CJ. The Listeria monocytogenes gene ctpA encodes a putative P-type ATPase involved in copper transport. Mol Gen Genet 1996.
4. 4 Nucifora G, Chu L, Misra TK, Silver S. Cadmium resistance from Staphylococcus aureus plasmid pI258 cadA gene results from cadmium-efflux ATPase. Proc Natl Acad Sci USA 1989; 86: 3544-8.
5. + antiporter (NhaA). J Bacteriol 1992; 174: 4878-84.
6. 6 Lebrun M, Audurier A, Cossart P. Plasmid-borne cadmium resistance genes in Listeria monocytogenes are similar to cad A and cadC of Staphylococcus aureus and are induced by cadmium. J Bacteriol 1994; 176: 3040-8.
7. 7 Kanamaru K, Kashiwagi S, Mizuno T. The cyanobacterium, Synechococcus sp. PCC7942, possesses two distinct genes encoding cation-transporting P-Type ATPases. FEBS Lett 1993; 330: 99-104.
8. 8 Phung LT, Ajlani G, Haselkorn R. P-Type ATPase from the cyanobacterium Synechococcus 7942 related to the human Menkes and Wilson disease gene products. Proc Natl Acad Sci USA 1994; 91: 9651-4.
9. 9 Odermatt A, Suter H, Krapf R, Solioz M. Primary structure of two P-Type ATPases involved in copper homeostasis in Enterococcus hirae. J Biol Chem 1993; 268: 12775-9.
10. 10 Ge Z, Hiratsuka K, Taylor DE. Nucleotide sequence and mutational analysis indicate that two Helicobacter pylori genes encode a P-Type ATPase and a cation-binding protein associated with copper transport. Mol Microbiol 1995; 15: 97-106.
11. 11 Melchers K, Weitzenegger T, Buhmann A, Steinhilber W, Sachs G, Schäfer KP. Cloning and membrane topology of a P-type ATPase from Helicobacter pylori. J Biol Chem 1996; 271: 446-57.
12. 12 Mertz W. The essential trace elements. Science 1981; 213: 1332-6.
13. 13 Brown NL, Rouch DA, Lee BTO. Copper resistance determinants in bacteria. Plasmid 1992; 27: 41-51.
14. g+ extrusion by CopB. Biochem Biophys Res Commun 1994; 202: 44-8.
15. 15 Brown NL, Lee BTO, Silver S. Metal ions in biological systems, vol 30. New York: Dekker, 1994: 405-34.
16. 16 Michel E, Reich KA, Favier R, Berche P, Cossart P. Attenuated mutants of the intracellular bacterium Listeria monocytogenes obtained by single amino acid substitutions in listeriolysin O. Mol Microbiol 1990; 4: 2167-78.
17. 17 Wuenscher MD, Köhler S, Goebel W, Chakraborty T. Gene disruption by plasmid integration in Listeria monocytogenes: insertional inactivation of the listeriolysis determinant lisA. Mol Gen Genet 1991; 228: 177-82.
18. 18 Wuenscher MD, Köhler S, Bubert A, Gerike U, Goebel W. The iap gene of Listeria monocytogenes is essential for cell viability, and its gene product, p60, has bacteriolytic activity. J Bacteriol 1993; 175: 3491-501.
19. 19 Domann E, Wehland J, Rohde M, Pistor S, Hartl M, Goebel W, Leimeister-Wachter M, Wuenscher M, Chakraborty T. A novel bacterial virulence gene in Listeria monocytogenes required for host cell microfilament interaction with homology to the proline-rich region of vinculin. EMBO J 1992; 11: 1981-90.
20. 20 Kocks C, Gouin E, Tabouret M, Berche P, Ohayon H, Cossart P. L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein. Cell 1992; 68: 521-31.
21. 21 Dramsi S, Biswas I, Maguin E, Braun L, Mastroeni P, Cossart P. Entry of Listeria monocytogenes into hepatocytes requires expression of InlB, a surface protein of the internalin multigene family. Mol Microbiol 1995; 16: 251-61.
22. 22 Mengaud J, Braun-Breton C, Cossart P. Identification of phosphatidylinositol-specific phospholipase C activity in Listeria monocytogenes: a novel type of virulence factor? Mol Microbiol 1991; 5: 367-72.
23. 23 Camilli A, Tilney LG, Portnoy DA. Dual roles of plcA in Listeria monocytogenes pathogenesis. Mol Microbiol 1993; 8: 143-57.
24. 24 Chakraborty T, Leimeister-Wächter M, Domann E, Hartl M, Goebel W, Nichterlein T, Notermans S. Coordinate regulation of virulence genes in Listeria monocytogenes requires the product of the prfA gene. J Bacteriol 1992; 174: 568-74.
25. 25 Freitag NE, Portnoy DA. Dual promoters of the Listeria monocytognes prfA transcriptional activator appear essential in vitro but are redundant in vivo. Mol Microbiol 1994; 12: 845-53.
26. 26 Portnoy DA, Jacks PS, Hinrichs DJ. Role of hemolysin for the intracellular growth of Listeria monocytogenes. J Exp Med 1988; 167: 1459-71.
27. 27 Camilli A, Paynton CR, Portnoy DA. Intracellular methicillin selection of Listeria monocytogenes mutants unable to replicate in a macrophage cell line. Proc Natl Acad Sci USA 1989; 86: 5522-6.
28. 28 Sun AN, Camilli A, Portnoy DA. Isolation of Listeria monocytogenes small-plaque mutants defective for intracellular growth and cell-to-cell spread. Infect Immun 1990; 58: 3770-8.
29. 29 Gaillard JL, Berche P, Sansonetti P. Transposon mutagenesis as a tool to study the role of hemolysin in the virulence of Listeria monocytogenes. Infect Immun 1986; 52: 50-5.
30. 30 Kathariou S, Metz P, Hof H, Goebel W. Tn916-induced mutations in the hemolysin determinant affecting virulence of Listeria monocytogenes. J Bacteriol 1987; 169: 1291-7.
31. 31 Cossart P, Vicente MF, Mengaud J, Baquero F, Perez-Diaz JC, Berche P. Listeriolysin O is essential for virulence of Listeria monocytogenes: direct evidence obtained by gene complementation. Infect Immun 1989; 57: 3629-36.
32. 32 Miller VL. Tissue-culture invasion: fact or artefact? Trends Microbiol 1995; 3: 69-71.
33. 33. Beisel WR. Magnitude of the host nutrional responses to infection. Am J Clin Nutr 1977; 30: 1236-47.
34. 34 Crocker A, Lee C, Aboko-Cole G, Durham C. Interaction of nutrition and infection: effect of copper deficiency on resistance to Trypanosoma lewisi. J Natl Med Assoc 1992; 84: 697-706.
35. 35 Matousek-de-Abel-de-la-Cruz AJ, Burguera JL, Burguera M, Anez N. Changes in the total content of iron, copper, and zinc in serum, heart, liver, spleen, and skeletal muscle tissues of rats infected with Trypanosoma cruzi. Biol Trace Elem Res 1993; 37: 51-70.
36. 36 Arroyo J, Hurley MC, Wolf M, McClain MS, Eisenstein BI, Engleberg NC. Shuttle mutagenesis of Legionella pneumophila: identification of a gene associated with host cell cytopathicity. Infect Immun 1994; 62: 4075-80.
37. 37 McClain MS, Hurley MC, Brieland JK, Engleberg NC. The Legionella pneumophila hel locus encodes intracellularly induced homologs of heavy-metal ion transporters of Alcaligenes spp. Infect Immun 1996; 64: 1532-40.
38. 38 Alexander JE, Andrew PW, Jones D, Roberts IS. Development of an optimized system for electroporation of Listeria species. Lett Appl Microbiol 1990; 10: 179-81.
39. 39 Park SF, Stewart GSAB. High efficiency transformation of Listeria monocytogenes by electroporation of penicillin-treated cells. Gene 1990; 94: 129-32.
40. 40 Trieu-Cuot P, Carlier C, Poyart-Salmeron C, Courvalin P. Shuttle vectors containing a multiple cloning site and a lacZα, gene for conjugal transfer of DNA from Escherichia coli to Gram-positive bacteria. Gene 1991; 102: 99-104.
41. 41 Trieu-Cuot P, Derlot E, Courvalin P. Enhanced conjugative transfer of plasmid DNA from Escherichia coli to Staphylococcus aureus and Listeria monocytogenes. FEMS Microbiol Lett 1993; 109: 19-24.
42. 42 Simon R, Priefer U, Puhler A. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in Gram-negative bacteria. Biotechnology 1983; 1: 784-94.
43. 43 Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
44. 44 Flamm RK, Hinrichs DJ, Thomashow MF. Introduction of pAMβ1. into Listeria monocytogenes by conjugation and homology between native L. monocytogenes plasmids. Infect Immun 1984; 44: 157-61.
45. 45 Bewsey KE, Johnson ME, Huff P. Rapid isolation and purification of DNA from agarose gels: the phenol-freeze-fracture method. BioTechniques 1991; 10: 724-5.
46. 45 Reed K. Basic blotting-a quick fix. Today's Life Sci 1990; 2: 52-60.
47. 47 Rathjen DA, Geczy CI. Conditioned medium from macrophage cell line supports the single-cell growth of hybridomas. Hybridoma 1986; 5: 255-61.
48. 48 Francis MS, Thomas CJ. Analysis of multiplicity of infection on Listeria monocytogenes pathogenicity of HeLa and Caco-2 cell lines. J Med Microbiol 1996; 45: 323-30.