Two enhancer domains control early aspects of the complex expression pattern of Msx1

Mechanisms of Development

Volumn 62, Issue 1, 1997, Pages 29-40

  MacKenzie, Alasdair ^a   Purdie, Lorna ^a   Davidson, Duncan ^a   Collinson, Martin ^a,b   Hill, Robert E ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

enhancer domains; homeobox gene; LacZ reporter gene; Msx1 promoter; transgenic mice

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMBRYO; ENHANCER REGION; GENE DELETION; GENE EXPRESSION REGULATION; GENE STRUCTURE; HISTOLOGY; HOMEOBOX; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENIC MOUSE;

ANIMALS; BASE SEQUENCE; DNA; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MSX1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS;

EID: 0031079721     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(96)00646-6     Document Type: Article

References (36)

1. Asakura, A., Lyons, G.E. and Tapscott, S.J. (1995) The regulation of MyoD gene expression: conserved elements mediate expression in embryonic axial muscle. Dev. Biol. 171, 386-398.
2. Bell. J.R., Noveen, A., Lui, Y.H., Ma, L., Dobias, S., Kundu, R., Luo, W., Xia, Y., Lusis, A.J., Snead, M.L. and Maxson, R. (1993) Genomic structure, chromosomal location and evolution of the mouse Hox-8 gene. Genomics 16, 123-131.
3. Brown, J.M., Wedden, S.E., Millburn, H.G.M., Robson, L.G., Hill, R.E., Davidson, D.R. and Tickle, C. (1993) Experimental analysis of the control of expression of the homeobox gene Msx1 in the developing limb and face. Development 119, 41-48.
4. Chan-Thomas, P.S., Thomson, R.P., Robert, B., Yacoub, M.H. and Barton, P.J.R. (1993) Expression of homeobox genes Msx1 and Msx2 during cardiac development in the chick. Dev. Dyn. 197, 203-216.
5. Coelho, C.D., Krabbenhoft, K.M., Upholt, W.B., Fallon, J.F. and Kosher, R.A. (1993) Ectoderm from various regions of the developing chick limb bud differentially regulates the expression of the chicken homeobox genes GHox-7 and GHox-8 by limb mesenchyme cells. Dev. Biol. 156, 303-306.
6. Davidson, D. (1995) The function and evolution of Msx genes: pointers and paradoxes. TIGS 11, 405-411.
7. Davidson, D.R. and Hill, R.E. (1991) Msh-like genes: a family of homeobox genes with wide ranging expression during vertebrate development. Semin. Dev. Biol. 2, 405-412.
8. Davidson, D.R., Crawley, A., Hill, R.E. and Tickle, C. (1991) Position dependency of two related homeobox genes in developing vertebrate limbs. Nature 352, 429-431.
9. Ehrich, E., Craig, H., Poustka, A., Frischauf, A.M. and Lehrach, H. (1987) A family of cosmid vectors with the multi-copy R6K replication origin. Gene 57, 229-237.
10. Hewitt, J.E., Clark. L.N., Ivens, I. and Williamson, R. (1991) Structure and sequence of the human homeobox gene HOX-7. Genomics 11, 670-678.
11. Hill, R.E., Jones, P.F., Rees, A.R., Sime, C.M., Justice, M.J., Copeland, N.G., Jenkins, N.A., Graham, E. and Davidson, D.R. (1989) A new family of mouse homeobox containing genes: molecular structure, chromosome location and developmental expression of Hox-7. Genes Dev. 3, 26-37.
12. Hogan, B., Constantini, F. and Lacy, E. (1986) Manipulating the Mouse Embryo. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
13. Holland, P.W.H. (1991) Cloning and evolutionary analysis of Msh like homeobox genes from mouse, zebrafish and ascidians. Gene 98, 253-257.
14. Jowett, A.K., Vainio, S., Ferguson, M.J.W., Sharpe, P.T. and Thesleff, I. (1993) Epithelial-mesenchymal interactions are required for Msx1 and Msx-2 gene expression in the developing murine molar tooth. Development 117, 461-470.
15. Krabbenhoft, K.M. and Fallon, J.F. (1992) Talpid limb bud mesoderm does not express GHox-8 and has altered expression pattern of GHox-7. Dev. Dyn. 194, 52-62.
16. Kuzuoka, M., Takahashi, T., Guron, C. and Raghow, R. (1994) Murine homeobox containing gene, Msx1: promoter structure and potential autoregulatory cis-acting elements. Genomics 21, 85-91.
17. Liu, Y.H., Ma, L., Wu, L.Y., Luo, W., Kundu, R., Sangiorgi, F., Snead, M.L. and Maxon, R. (1994) Regulation of the Msx-2 homeobox gene during mouse embryogenesis: a transgene with 439 bp of 5′ flanking sequence is expressed exclusively in the apical ectodermal ridge of the developing limb. Mech. Dev. 48, 187-197.
18. Lyons, G.E., Houzelstein, D., Sassoon, D., Robert, B. and Buckingham, M.E. (1992) Multiple sites of Hox-7 expression during mouse embryogenesis: comparison with retinoic acid receptor mRNA location. Mol. Reprod. Dev. 32, 303-314.
19. MacKenzie, A., Leeming, G.L., Jowett, A.K., Ferguson, M.W.J. and Sharpe, P.T. (1991a) The homeobox containing gene Hox-7 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro. Development 111, 269-285.
20. MacKenzie, A., Ferguson, M.J.W. and Sharpe, P.T. (1991b) Hox-7 expression during murine craniofacial development. Development 113, 601-611.
21. MacKenzie, A., Ferguson, M.J.W. and Sharpe, P.T. (1992) Expression patterns of the homeobox gene, Hox-8, in the mouse embryo suggest a role in specifying tooth initiation and shape. Development 115, 403-420.
22. Monaghan, A.P., Davidson, D.R., Sime, C., Graham, E., Baldcock, R., Bhattacharya, S.S. and Hill, R.E. (1991) The Msh-like homeobox genes define domains in the developing vertebrate eye. Development 112, 1053-1061.
23. Prestridge, D.S. (1991) Signal scan: a computer programme that scans DNA sequences for eukaryotic transcriptionaf elements. CABIOS 7, 203-206.
24. Robert, B., Sassoon, D., Jacq, B., Gehring, W. and Buckingham, M. (1989) Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis. EMBO J. 8, 91-100.
25. Robert, B., Lyons, G., Simandl, B.K., Kuroiwa, A. and Buckingham, M. (1991) The apical ectodermaJ ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds. Genes Dev. 5, 2363-2374.
26. Sambrook, J., Frisch, E.F. and Maniatis, T. (1989) Molecular Cloning: a Laboratory Manual (2nd edn.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 5.45-5.47.
27. Sanes, J.K., Rubenstein, J.L.R. and Nicolas, J.F. (1986) Use of a recombinant retrovirus to study post implantation cell lineage in mouse embryos. EMBO J. 5, 3133-3142.
28. Shen, R., Chen, Y., Huang, L., Vitale, E. and Solursh, M. (1994) Characterisation of the human MSX-1 promoter and an enhancer responsible for retinoic acid induction. Cell. Mol. Biol. Res. 40, 297-312.
29. Song, K., Wang, Y. and Sassoon, D. (1992) Expression of Msx1 on myoblasts inhibits terminal differentiation and induces cell transformation. Nature 360, 477-481.
30. Sumoy, L., Wang, C.K.L., Lichtler, A.C., Pierro, L.T., Kosher, R.A. and Upholt, W.B. (1995) Identification of a spatially specific enhancer element in the chicken Msx2 gene that regulates its expression in the apical ectodermal ridge of the developing limb buds of transgenics mice. Dev. Biol. 170, 230-242.
31. Takahashi, Y. and Le Douarin, N. (1990) cDNA cloning of a quail homeodomain gene and its expression in neural crest derived mesenchyme and lateral plate mesoderm. Proc. Natl. Acad. Sci. USA 87, 7482-7486.
32. Takahashi, Y., Monsoro-Burq, A., Bontoux, M. and Le Douarin, N.M. (1992) A role for Quox-8 in the establishment of the dorsoventral pattern during vertebrate development. Proc. Natl. Acad. Sci. USA 89, 10237-10241.
33. Wang, Y. and Sassoon, D. (1995) Ectoderm-mesenchyme and mesenchyme-mesenchyme interactions regulate Msx1 expression and cellular differentiation in the murine limb bud. Dev. Biol. 168, 374-382.
34. Woloshin, P., Song, K., Degnin, C., Killary, A.M., Goldhammer, D.G., Sassoon, D. and Thayer, M.J. (1995) MSX1 inhibits MyoD expression in fibroblasts × 10T1/2 cell hybrids. Cell 82, 611-620.
35. Yee, S.P. and Rigby, P.W.J. (1993) The regulation of Myogenin gene expression during the embryonic development of the mouse. Genes Dev. 7, 1277-1289.
36. Yokouchi, Y.R., Ohshugi, K., Sasaki, H. and Kuroiwa, A. (1991) Chicken homeobox gene Msx1: structure, expression in limb buds and effects of retinoic acid. Development 113, 431-444.