In vitro degradation of poly(caprolactone), poly(lactide) and their block copolymers: Influence of composition, temperature and morphology

Reactive and Functional Polymers

Volumn 32, Issue 2, 1997, Pages 161-168

  Ye, Wei Ping ^a   Du, Fu Sheng ^a   Jin, Wei Hua ^a   Yang, Ji Yuan ^a   Xu, Yong ^a  

^a NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

Author keywords

Activation energy; Apparent rate constant; Block copolymer; In vitro degradation; Microphase separation

Indexed keywords

ACTIVATION ENERGY; BIOPOLYMERS; BLOCK COPOLYMERS; COMPOSITION EFFECTS; MONITORING; PHASE SEPARATION; THERMAL EFFECTS; VISCOSITY;

APPARENT RATE CONSTANT; ARRHENIUS PLOT; IN VITRO DEGRADATION; MICROPHASE SEPARATION; PHOSPHATE BUFFER SOLUTION; POLYCAPROLACTONE; POLYLACTIDE; RESIDUAL WEIGHT;

DEGRADATION;

EID: 0031079426     PISSN: 13815148     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1381-5148(96)00081-8     Document Type: Article

References (29)

1. T.H. Barrows, Clin. Mater., 1 (1986) 233.
2. M. Vert, Angew. Makromol. Chem., 166/167 (1989) 155.
3. J. Kohn, Med. Device Technol., 1 (1990) 34.
4. J. Heller, CRC Crit. Rev. Ther. Drug Carrier Syst., 1 (1984) 39.
5. S.J. Holland and B.J. Tighe, in: D. Ganderton and T.J. Jones (Eds.), Advances in Pharmaceutical Sciences, 6. Academic Press, London, 1992, p. 101.
6. R. Arshady, J. Controlled Release, 17 (1991) 1.
7. T.H. Barrows, Clin. Mater, 1 (1986) 233.
8. S.X. Wu, in: D.L. Wise (Ed.), Encyclopedic Handbook of Biomaterials and Bioengineering. Marcel Dekker, New York, NY 1995, p. 1015.
9. H. Pistner, D.R. Bendix, J. Muhling and J.F. Reuther, Biomaterials, 14 (1993) 291.
10. T.G. Park, J. Controlled Release, 30 (1994) 161.
11. J. Heller, J. Controlled Release, 16 (1991) 3.
12. M. Chasin, A. Domb, E. Ron, E. Matthiowits, R. Langer, K. Leong, C. Laurencin, H. Brem and S. Grossman, in: M. Chasin and R. Langer (Eds.), Biodegradable Polymers as Drug Delivery Systems. Marcel Dekker, New York, NY, 1990, p. 43.
13. S.J. Holland, B.J. Tighe and P.L. Gould, J. Controlled Release, 4 (1986) 155.
14. S.M. Li, H. Garreau and M. Vert, J. Mater. Sci., Mater. Med., 1 (1990) 123.
15. C.G. Pitt, A.R. Jeffcoat, R.A. Zweidinger and A. Schindler, J. Biomed. Mat. Res., 13 (1979) 497.
16. C.G. Pitt, D. Christenses, A.R. Jeffcoat, G.L. Kimmel, A. Schindler, M.E. Wall and R.A. Zweidinger, in: H.L. Gabelnick (Ed.), Proceedings Drug Delivery System. DHEW Pub. No. (NIH) 77-1238, 1977, pp. 141.
17. X.D. Feng, C.X. Song and H.Y. Chen, J. Polym. Sci., Letter Ed., (1983) 593.
18. Y.X. Li, Ph.D. Thesis, Peking University, Beijing, 1988.
19. W.P. Ye and Y.W. Chien, J. Pharm. Develop. Technol., 1 (1996) 1.
20. W.P. Ye and Y.W. Chien, J. Controlled Release, 41 (1996) 259.
21. Z.W. Gu, W.P. Ye, J.Y. Yang, Y.X. Li, X.L. Chen, G.W. Zhong and X.D. Feng, J. Controlled Release, 22 (1992) 3.
22. V. Crescenzi, G. Manzini, G. Calzolari and C. Borri, Eur. Polym. J., 8 (1972) 449.
23. C.G. Pitt and Z.W. Gu, J. Controlled Release, 4 (1987) 283.
24. R.D. Gilbert, V. Stannett, C.G. Pitt and A. Schindler, in: N. Grassie (Ed.), Developments in Polymer Degradation, 4. Applied Science Publ., London, 1982, p. 259.
25. A. Nosha and J.E. McGrath, in: Block copolymers. Academic Press, New York, NY, 1977, p. 7.
26. J.V. Dawkins, in: D.C. Allport (Ed.), Block Copolymers. Applied Science Publ., London, 1973, p. 363.
27. O.F. Solomon and I.Z. Ciuta, J. Appl. Polym. Sci., 6 (1962) 683.
28. H.-G. Elias (Ed.), in: Macromolecules, 2. Plenum Press, New York, NY, 1977, p. 576.
29. K. Makino, M. Arakawa and T. Kondo, in: E. Drioli (Ed.), Proceedings of the European-Japanese Congress of Membrane and Membrane Process. Nagasaki, 1986, p. 371.