Transforming Growth Factor-β1 Responsiveness of Human Articular Chondrocytes in Vitro: Normal Versus Osteoarthritis

Yonsei Medical Journal

Volumn 38, Issue 1, 1997, Pages 40-51

  Jahng, Jun Seop ^a   Lee, Jin Woo ^a   Han, Chang Dong ^a   Kim, Sung Jae ^a   Yoo, Nae Choon ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Chondrocyte; Monolayer culture; Osteoarthritis; Transforming growth factor 1

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; ARTICULAR CARTILAGE; CELL CULTURE; CELL DIVISION; CYTOLOGY; DRUG EFFECT; HUMAN; OSTEOARTHRITIS; PATHOLOGY; REFERENCE VALUE;

CARTILAGE, ARTICULAR; CELL DIVISION; CELLS, CULTURED; HUMANS; OSTEOARTHRITIS; REFERENCE VALUES; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031067530     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.1997.38.1.40     Document Type: Article

References (49)

1. Abyad A, Boyer JT: Arthritis and aging. Curr Opin Rheumatol 4: 153-159, 1992
2. Benya PD, Shaffer JD: Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gel. Cell 30: 215-224, 1982
3. Brittberg M, Faxen E, Peterson L: Carbon fiber scaffolds in the treatment of early knee osteoarthritis. Clin Orthop 307: 155-164, 1994a
4. Brittberg M, Lindahl A, Nilsson A, Ohlsson C, Isaksson O, Peterson L: Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 331: 889-895, 1994b
5. Bulstra SK, Buurman WA, Walenkamp GH, Van der Linden AJ: Metabolic characteristics of in vitro cultured human chondrocytes in relation to the histopathologic grade of osteoarthritis. Clin Orthop 242: 294-302, 1989
6. Carrington JL, Roberts AB, Flanders KC, Roche NS, Reddie AH: Accumulation, location, and compartmentation of transforming growth β during endochondral bone development. J Cell Biol 107: 1969-1975, 1988
7. Chandrasekhar S, Harvey AK: Transforming growth factor-β is a potent inhibitor of IL-1 induced protease activity and cartilage proteoglycan degradation. Biochem Biophys Res Commun 157: 1352-1359, 1988
8. Convery FR, Akeson WH, Keown GH: The repair of large osteochondral defects: an experimental study in horses. Clin Orthop 82: 253-262, 1972
9. Dingle JT, Davies ME, Mativi BY, Middleton HF: Immunohistochemical identification of interleukin-1 in activated chondrocytes. Ann Rheum Dis 49: 889-897, 1990
10. Ewing JW: Arthroscopic treatment of degenerative meniscal lesions and early degenerative arthritis of the knee. In Ewing JW, ed. Articular cartilage and knee joint function. New York, Raven Press, 1990, 137-145
11. Ficat RP, Ficat C, Gedeon PK, Toussaint JF: Spongialization: a new treatment for diseased patellae. Clin Orthop 182: 200-205, 1984
12. Frazer A, Seid JM, Hart KA, Bentley H, Bunning RA, Russell RG: Detection of mRNA for the transforming growth factor beta family in human articular chondrocytes by the polymerase chain reaction. Biochem Biophys Res Commun 180: 602-608, 1991
13. Friedman MJ, Berasi DO, Fox JM, Pizzo WD, Snyder SJ, Ferkel RD: Preliminary results with abrasion arthroplasty in the osteoarthritic knee. Clin Orthop 182: 200-205, 1984
14. Furukawa T, Eyre DR, Koide DR, Glimcher MJ: Biochemical studies on repair cartilage resurfacing experimental defects in the rabbit knee. J Bone Joint Surg 62A: 79-89, 1980
15. 1) on matrix synthesis by monolayer cultures of rabbit articular chondrocytes during the dedifferentiation process. Exp Cell Res 200: 379-392, 1992
16. Gross AE, Beaver RJ, Mohammed MN: Fresh fragment osteochondral allografts used for posttraumatic defects in the knee joint. In Finerman GAM, ed. Biology and biomechanics of the traumatized synovial joint. Rosemont IL, American Academy of Orthopaedic Surgeons, 1992, 123-141
17. Guerne PA, Blanco F, Kaelin A, Desgeorges A, Lotz M: Growth factor responsiveness of human articular chobdrocytes in aging and development. Arthritis Rheum 38: 7: 960-968, 1995
18. Guerne PA, Carson DA, Lotz M: IL-6 production by human articular chondrocytes: modulation of its synthesis by cytokines, growth factors, and hormones in vitro. J Immunol 144: 499-505, 1990
19. Guerne PA, Sublet A, Lotz M: Growth factor responsiveness of human articular chondrocytes: distinct profiles in primary chondrocytes, subcultured chondrocytes, and fibroblasts. J Cell Physiol 158: 476-484, 1994
20. Hamerman D: Aging and osteoarthritis: basic mechanisms. J Am Geriatr Soc 41: 760-770, 1993
21. Homminga GN, Bulstra SK, Bouwmeester PM, Linden AJVD: Perichondrial grafting for cartilage lesion of the knee. J Bone Joint Surg 72B: 1003-1007, 1990
22. Horton WE, Higginbotham JD, Chandrasekhar S: Transforming growth factor-beta and fibroblast growth factor act synergistically to inhibit collagen II synthesis through a mechanism involving regulatory DNA sequences. J Cell Physiol 141: 8-15, 1989
23. Hunziker EB, Rosenberg LC: Induction of repair partial thickness articular cartilage lesions by timed release of TGF-beta. Trans Orthop Res Soc 19: 236, 1994
24. Hunziker EB, Rosenberg LC: Repair of partialthickness defects in articular cartilage: cell recruitment from the synovial membrane. J Bone Joint Surg 78A: 721-733, 1996
25. Inoue H, Kato Y, Iwamoto M, Hiraki Y, Sakuda M, Suzuki F: Stimulation of cartilage-matrix proteoglycan synthesis by morphological transformed chondrocytes grown in the presence of fibroblast growth factor and transforming growth factorbeta. J Cell Physiol 138: 329-337, 1989
26. Iwamoto M, Sato K, Nakashima K, Fuchihata H, Suzuki F, Kato Y: Regulation of colony formation of differentiated chondrocytes in soft agar by transforming growth factor-beta. Biochem Biophys Res Commun 159: 3: 1006-1011, 1989
27. Johnson LL: Arthroscopic abrasion arthroplasty. Historical and pathological perspective: present status. Arthroscopy 2: 54-59, 1986
28. Lotz M, Terkeltaub R, Villiger PM: Cartilage and joint inflammation regulation of IL-8 expression by human articular chondrocytes. J Immunol 148: 466-473, 1992
29. Mankin H: Current concepts review. The response of articular cartilage to mechanical injury. J Bone Joint Surg 64A: 460-466, 1982
30. Mankin HJ, Dorfman H, Lippiello L, Zarins A: Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic hips. J Bone Joint Surg 53A: 523-537, 1971
31. Meachim G, Roberts C: Repair of the joint surface from subarticular tissue in rabbit knee. J Anat 109: 317-327, 1971
32. Meyers MH, Akeson W, Convery FR: Resurfacing the knee with fresh osteochondral allografts. J Bone Joint Surg 71A: 704-713, 1989
33. Miura Y, Fitzsimmons JS, Commisso CN, Gallay SH, O'Driscoll SW: Enhancement of periosteal chondrogenesis in vitro. Dose response for transforming growth factor-beta 1(TGF-β). Clin Orthop 301: 271-280, 1994
34. Morales TI, Joyce ME, Sobel ME, Roberts AB: Autocrine production of TGF-β by calf articular cartilage. Trans Orthop Res Soc 15: 109, 1990
35. Muckle DS, Minns RJ: Biological response to woven carbon fiber pads in the knee: a clinical and experimental study. J Bone Joint Surg 72B: 60-62, 1990
36. Nilsson A, Isgaard J, Lindahl A, Dahlstrom A, Skottner A, Isaksson OG: Regulation by growth hormone of number of chondrocytes containing IGF-I in rat growth plate. Science 233: 571-574, 1986
37. Peracchia F, Ferrari G, Poggi A, Rotilio D: IL-1 beta induced expression of PDGF-AA isoform in rabbit articular chondrocytes is modulated by TGF-beta 1. Exp Cell Res 193: 208-212, 1991
38. Redini F, Daireaux M, Mauviel A, Galera P, Loyau G, Pujol JP: Characterization of proteoglycans synthesized by rabbit articular chondrocytes in response to transforming growth factor-beta (TGF-β). Biochem Biophys Acta 1093: 196-206, 1991
39. Roberts AB, Anzano MA, Lamb LC, Smith JM, Sporn MB: New class of transforming growth factors potentiated by epidermal growth factor: Isolation from non-neoplastic tissues. Proc Natl Acad Sci USA 78: 5339-5343, 1981
40. Rosen DM, Stempien SA, Thompson AY, Seyedin SM: Transforming growth factor-beta modulates the expression of osteoblast and chondroblast phenotypes in vitro. J Cell Physiol 134: 337-346, 1988
41. Rosier RN, O'Keefe BJ, Grabb ID, Puzas JE, Brand JS: Articular and growth plate chondrocytes exhibit markedly different metabolic responses to growth factors. J Bone Miner Res 3: S185, 1988
42. Rosier RN, O'Keefe BJ, Grabb ID, Puzas JE: Transforming growth factor beta: an autocrine regulator of chondrocytes. Connect Tissue Res 20: 295-301, 1989
43. Rossi P, Karsenty G, Roberts AB, Roche NS, Sporn MB, De Crombrugghe B: A nuclear factor 1 binding mediates the transcriptional activation of a type I collagen promotor by transforming growth factor-beta. Cell 52: 405-414, 1988
44. Sandell EJ, Dudek BB, Wight TN: Regulation of cartilage collagen and proteoglycan synthesis by transforming growth factor-B. Orthop Trans 13: 342, 1989
45. Schiltz JR, Mayne R, Holtzer H: The synthesis of collagen and glycosaminoglycans by dedifferentiated chondroblasts in culture. Cell Differentiation 1: 97-108, 1973
46. Skantze KA, Brinckerhoff CE, Collins JP: Use of agarose culture to measure the effect of transforming growth factor β and epidermal growth factor on rabbit articular chondrocytes. Cancer Res 45: 4416-4421, 1985
47. Villiger PM, Lotz M: Differential expression of TGF beta isoforms by human articular chondrocytes in response to growth factors. J Cell Physiol 151: 318-325, 1992
48. Villiger PM, Terkeltaub R, Lotz M: Monocyte chemoattractant protein-1 (MCP-1) expression in human articular cartilage induction by peptide regulatory factors and differential effects of dexamethasone and retinoic acid. J Clin Invest 90: 488-496, 1993
49. Von der Mark K, Gauss V, Von der Mark H, Muller P: Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture. Nature 267: 531-532, 1977