The effect of aging on glucose tolerance and B cell secretion in man;Wpływ wieku na tolerancjȩ glukozy i czynność wydzielnicza̧ komórek B wysp trzustkowych

Polskie Archiwum Medycyny Wewnetrznej

Volumn 97, Issue 2, 1997, Pages 112-119

  Dembe, Krzysztof ^a   Karnafel, Waldemar ^a   Pacuła, Piotr ^a  

^a Kat I Klinika Gastroenterologii I

Author keywords

Aging; Glucose tolerance; Serum C peptide; Serum insulin

Indexed keywords

C PEPTIDE; INSULIN;

ADAPTATION; ADOLESCENT; ADULT; AGED; AGING; ARTICLE; BLOOD; BODY MASS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HUMAN; LIVER; MALE; METABOLISM; MIDDLE AGED; PANCREAS ISLET; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; BLOOD GLUCOSE; BODY MASS INDEX; C-PEPTIDE; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; ISLETS OF LANGERHANS; LIVER; MALE; MIDDLE AGED;

EID: 0031063456     PISSN: 00323772     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. De Fronzo R.: Glucose intolerance and aging. Diabetes Care, 1981, 4, 493.
2. Shimokata H., Muller D.: Age as independent determinant of glucose tolerance. Diabetes, 1991, 40, 44.
3. Dual R.: Einsinck J.: Insulin and glucagon relationship during aging in man. Metabolism, 1977, 26, 33.
4. Czyżyk A.: Patofizjologia i klinika cukrzycy. Warszawa, PZWL, 1987.
5. Faber O., Hagen C.: Kinetics of human connecting peptide in normal and diabetic sucjects. J. Clin. Invest., 1978, 62, 97.
6. Polonsky K., Jaspan J.: The metabolism of C-peptide in the dog. In vivo demonstration of the absence oh hepatic extraction. J. Clin. Invest., 1983, 72, 1114.
7. Weir G., Leahy J.: Experimental reduction of ß-cell mass: implications for the pathogenesis of diabetes. Diabetes Metab. Rev., 1986, 2, 125.
8. Duckworth W., Kitachi A.: The effect of age on plasma proinsulin-like material after oral glucose. J. Lab. Clin. Med., 1976, 88, 3459.
9. Bolinder J., Östman J.. Influence of aging on insulin receptor binding and metabolic effects of on human adipose tissue. Diabetes, 1983, 32, 959.
10. Kono S., Kuzuva H.: Changes in insulin receptor kinase with aging in rat skeletal muscle and liver. Am. J. Physiol, 1990, 259, 27.
11. Fulop T., Nagy J.: Glucose intolerance and insulin resistance with aging studies on insulin receptors and post receptors events. Arch. Gerontol. Geriatr., 1987, 6, 107.
12. Robert J., Commins J.: Quantitative aspects of glucose production and metabolism in healthy of aging on hepatic and peripheral glucose metabolism in human. Diabetes, 1988, 37, 119.
13. Boden G., Chen X.: Effects of age and body fat on insulin resistance in healthy men. Diabetes Care, 1993, 15, 728.
14. Kahn S., Larson V.. Effect of exercise on insulin action, glucose tolerance and insulin secretion in aging. Am. J. Physiol. 1990, 258, 937.
15. Hollenbeck C., Haskeel W.: Effect of habitual physical activity on regulation of insulin-stimulated glucose disposal in older males. J. am. Geriatr. Soc., 1985, 33, 273.
16. Mitsukawa T., Taemura J.: Effects of aging on plasma islet amyloid polypeptide basal level and response to oral glucose load. Diabetes Res. Clin. Pract., 1992, 15, 131.
17. Bogards C., Lillioja S.: Relationship between insulin secretion, insulin action, fasting plasma glucose concentration in nondiabetic and noninsulin dependent diabetic subjects. J. Clin. Invest., 1984, 74, 1238.
18. Ferrae., Vichi S., Beck-Nielsen H. i wsp.: Insulin action and age. Diabetes, 1996, 45, 947.