Role of KATP channels in the cardioprotection provided by ischemic preconditioning in anesthetized rabbits

Acta Physiologica Sinica

Volumn 49, Issue 1, 1997, Pages 105-109

  Ding, Yan Feng ^a   He, Rui Rong ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

ATP sensitive potassium channel; Ischemia reperfusion; Ischemic preconditioning; Myocardial infarct size

Indexed keywords

ADENOSINE TRIPHOSPHATE; CROMAKALIM; POTASSIUM CHANNEL; VASODILATOR AGENT;

ACTIVE TRANSPORT; ANIMAL; ARTICLE; HEART INFARCTION; HEART INFARCTION PREVENTION; MALE; METABOLISM; PATHOLOGY; RABBIT;

ADENOSINE TRIPHOSPHATE; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CROMAKALIM; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MYOCARDIAL INFARCTION; POTASSIUM CHANNELS; RABBITS; VASODILATOR AGENTS;

EID: 0031061814     PISSN: 03710874     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Lawson CS, Downey JM. Preconditioning: state of the art myocardial protection. Cardiovasc Res, 1993, 27: 542-550
2. ATP channels in ischaemic preconditioniong. Cardiovasc Res, 1994, 28:783-787
3. Gross GJ, Auchampach JA. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs. Circ Res, 1992, 70:223-233
4. Auchampach JA, Grover GJ, Gross, GJ. Blockade of ischaemic preconditioning in dogs by the novel ATP dependent potassium channel antagonist sodium 5-hydroxydecanoate. Cardiovasc Res, 1992, 26:1054-1062
5. ATP) opener bimakalim mimics preconditioning protection in swine. (Abstract) Circulation, 1992, 86:I-555
6. Thornton JD, Thornton CS, Sterling DL, et al. Blockade of ATP-sensitive potassium channels increases infarct size but does not prevent preconditioning in rabbit hearts. Circ Res , 1993, 72:44-49
7. Toombs CF, Moore TL, Shebuski RJ. Limitation of infarct size in the rabbit by ischaemic preconditioning is reversible with glibenclamide. Cardiovasc Res, 1993, 27: 617-622
8. Toombs CF, Norman NR, Groppi VE, et al. Limitation of myocardial injury with the potassium channel opener cromaklim and the nonvasoactive analog U-89, 232: vascular vs. cardiac actions in vitro and in vivo. J Pharmacol Exp Ther, 1992, 263:1261-1268
9. ATP channel antagonist to attenuate preconditioning in rabbit myocardium. Cardiovasc Res, 1994, 28:1337-1341
10. Miura T, Goto M, Miki T, et al. Glibenclamide, a blocker of ATP-sensitive potassium channels, abolishes infarct size limitation by preconditioning in rabbits anesthetized with xylazine/pentobarbital but not with pentobarbital alone. J Cardiovasc Pharmacol, 1995, 25: 531-538
11. Grover GJ, Sleph PG, Dzwonczyk S. Pharmacologic profile of cromakalim in the treatment of myocardial ischemia in isolated rats hearts and anesthetized dogs. J Cardiovasc Pharmacol, 1990, 16: 853-864
12. + channels protect the myocardium against ischemia/ reperfusion damage. Circ Res, 1991, 69:571-581
13. Grover GJ. Protective effects of ATP sensitive potassium channel openers in models of myocardial ischemia. Cardiovasc Res, 1994, 28:778-782
14. Liu Y, Downey JM. Ischemic preconditioning protects against infarction in rat heart. Am J Physiol, 1992, 263:H1107-H1112