Possible control of dopamine β-hydroxylase via a codominant mechanism associated with the polymorphic (GT)n repeat at its gene locus in healthy individuals

Human Genetics

Volumn 99, Issue 1, 1996, Pages 52-55

  Wei, Jun ^a   Ramchand, C N ^a   Hemmings, Gwynneth P ^a  

^a Schizophrenia Assoc of Gt Britain   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE BETA MONOOXYGENASE;

ADULT; ALLELE; ARTICLE; ENZYME REGULATION; FEMALE; GENE FREQUENCY; GENE LOCUS; GENOTYPE; HUMAN; MALE; NORMAL HUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ALLELES; BASE SEQUENCE; DINUCLEOTIDE REPEATS; DNA PRIMERS; DOPAMINE BETA-HYDROXYLASE; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; REFERENCE VALUES;

EID: 0031060684     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390050310     Document Type: Article

References (31)

1. Asamoah A, Wilson AF, Elston RC, Dalferes E Jr, Berenson GS (1987) Segregation and linkage analyses of dopamine-beta-hydroxylase activity in a six-generation pedigree. Am J Med Genet 27:613-621
2. Biaggioni I, Goldstein DS, Atkinson T, Robertson D (1990) Dopamine-beta-hydroxylase deficiency in humans. Neurology 40:370-373
3. Bouloux P, Perrett D, Besser GM (1985) Methodological considerations in the determination of plasma catecholamine by high-performance liquid chromatography with electrochemical detection. Ann Clin Biochem 22:194-203
4. Charlesworth B, Sniegowski P, Stephan W (1994) The evolutionary dynamics of repetitive DNA in eukaryotes. Nature 371:215-220
5. Craig SP, Buckle VJ, Lamouroux A, Mallet J, Craig IW (1988) Localization of the human dopamine-beta-hydroxylase (DBH) gene to chromosome 9q34. Cytogenet Cell Genet 48:48-50
6. Dunnette J, Weinshilboum R (1982) Family studies of plasma dopamine-β-hydroxylase thermal stability. Am J Hum Genet 34:84-99
7. Fujita K, Ito T, Maruta K, Teradaira R, Beppu H, Nakagami Y, Kato Y, Nagatsu T, Kato T (1978) Serum dopamine-β-hydroxylase in schizophrenic patients. J Neurochem 30:1569-1572
8. Gentric A, Fouilhoux A, Caroff M, Mottier D, Jouquan J (1993) Dopamine-β-hydroxylase deficiency responsible for severe dysautonomic orthostatic hypotension in an elderly patient. J Am Geriatr Soc 41:550-551
9. Goldin LR, Gershon ES, Lake CR, Murphy DL, McGinniss M, Sparkes RS (1982) Segregation and linkage studies in plasma dopamine-beta-hydroxylase (DBH), erythrocyte catechol-O-methyltransferase (COMT), and platelet monoamine oxidase (MAO): possible linkage between the ABO locus and a gene controlling DBH activity. Am J Hum Genet 34:250-262
10. Hartman BK (1973) Immunofluorescence of dopamine-β-hydroxylase: application of improved methodology to the localization of the peripheral and central noradrenergic nervous system. J Histochem Cytochem 21:312-332
11. Kammen DP van, Mann LS, Sternberg DE, Scheinin M, Ninan PT, Marder SR, Kammen WB van, Rieder RO, Linnoila M (1983) Dopamine-β-hydroxylase activity and homovanillic acid in spinal fluid of schizophrenics with brain atrophy. Science 220:974-976
12. Lake CR, Ziegler MG, Coleman M, Kopin IJ (1977) Lack of correlation of plasma norepinephrine and dopamine-β-hydroxylase in hypertensive and normotensive subjects. Circ Res 41:865-869
13. Lamprecht F, Andres R, Kopin IJ (1975) Serum dopamine-β-hydroxylase: constancy of levels in normotensive adults and decreases with development of blood pressure elevation. Life Sci 17:749-754
14. Markianos ES, Nyström I, Reichel H, Matussek N (1976) Serum dopamine-β-hydroxylase in psychiatric patients and normals. Effect of d-amphetamine and haloperidol. Psychopharmacology 50:259-267
15. Melter HY, Cho HW, Carroll BJ, Russo P (1976) Serum dopamine beta-hydroxylase activity in the affective psychoses and schizophrenia. Arch Gen Psychiatry 33:585-591
16. Nagatsu T, Udenfriend S (1972) Photometric assay of dopamine-β-hydroxylase activity in human blood. Clin Chem 18:980-983
17. n sequences upstream of the rat prolactin gene form Z-DNA and inhibit gene transcription. Nucleic Acids Res 18:1595-1601
18. Porter CJ, Nahmias J, Wolfe J, Craig IW (1992) Dinucleotide repeat polymorphism at the human dopamine β-hydroxylase (DBH) locus. Nucleic Acids Res 20:1429
19. Robertson D, Haile V, Perry SE, Robertson RM, Phillips JA, Biaggioni I (1991) Dopamine beta-hydroxylase deficiency - a genetic disorder of cardiovascular regulation. Hypertension 18:1-8
20. Robertson D, Mosquedagarcia R, Robertson RM, Biaggioni I (1992) Chronic hypotension - in the shadow of hypertension. Am J Hypertens 5 : S200-S205
21. Schanberg SM, Stone RA, Kirshner N, Gunnells JC, Robinson RR (1974) Plasma dopamine beta-hydroxylase: a possible aid in the study and evaluation of hypertension. Science 183:523-525
22. n sequences in human and rodent genomes. J Biomol Struct Dyn 9:387-397
23. Wei J, Ramchand CN, Hemmings GP (1992) Studies on concentrations of NA and HVA and activity of DBH in the serum from schizophrenic patients, first-degree relatives and normal subjects. Schizophr Res 8:103-110
24. Weinshilboum RM (1983) Biochemical genetics of catecholamines in humans. Mayo Clin Proc 58:319-330
25. Weinshilboum RM, Axelrod J (1971) Reduced plasma dopamine-β-hydroxylase activity in familial dysautonomia. N Engl J Med 285:938-942
26. Weinshilboum RM, Thoa NB, Johnson DG, Kopin IJ, Axelrod J (1971) Proportional release of norepinephrine and dopamine-β-hydroxylase from sympathetic nerves. Science 174:1349-1351
27. Weinshilboum RM, Raymond FA, Elveback LR, Weidman WH (1973) Serum dopamine-β-hydoxylase activity: sibling-sibling correlation. Science 181:943-945
28. Weinshilboum RM, Schrott HG, Raymond FA, Weidman WH, Elveback LR (1975) Inheritance of low serum dopamine-β-hydroxylase activity. Am J Hum Genet 27:573-585
29. Wise CD, Stein L (1973) Dopamine-β-hydroxylase deficits in the brains of schizophrenic patients. Science 181:344-347
30. 2 gene. Nucleic Acids Res 22:5093-5098
31. Wyatt RJ, Schwartz MA, Erdelyi E, Barchas JD (1975) Dopamine-β-hydroxylase activity in brains of chronic schizophrenic patients. Science 187:368-370