Heterotrimeric G-proteins and development

Biochemical Pharmacology

Volumn 53, Issue 1, 1997, Pages 1-4

  Malbon, Craig C ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

development; G proteins; MAPK; tyrosine kinases

Indexed keywords

ADENYLATE CYCLASE; CYCLIC GMP PHOSPHODIESTERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; ION CHANNEL; MEMBRANE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C; PROTEIN SUBUNIT; PROTEIN TYROSINE KINASE;

CELL DIFFERENTIATION; CELL TYPE; DEVELOPMENT; HUMAN; MUTANT; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION;

EID: 0031060659     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00662-4     Document Type: Note

References (28)

1. Simon MI, Strathmann MP and Gautam N, Diversity of G proteins in signal transduction. Science 252: 802-808, 1991.
2. Clapham DE and Neer EJ, New roles for G protein beta/ gamma dimers in transmembrane signalling. Nature 365: 403-406, 1993.
3. Gilman AG, G Proteins: Transducers of receptor-generated signals. Annu Rev Biochem 56: 615-649, 1987.
4. oα is a major growth cone protein subject to regulation by GAP-43, Nature 344: 836-841, 1990.
5. Strittmater SM, Valenzuela D, Kennedy TE, Neer EJ and Fishman MC, Mediation by G-proteins of signals that cause collapse of growth cones. Science 259: 77-79, 1993.
6. Green H and Kehinde O, Sublines of mouse 3T3 cells that accumulate lipid. Cell 1: 113-116, 1974.
7. s protein α-subunit sequence accelerate differentiation of fibroblasts to adipocytes. Nature 358: 334-337, 1992.
8. iα2 axis controls adipogenesis independently of adenylylcyclase. Int J Obesity 20: 26-31, 1996.
9. Strickland S and Mahdavi V, The induction of differentiation in teratocarcinoma cells by retinoic acid. Cell 15: 393-403, 1978.
10. Galvin-Parton PA, Watkins DC and Malbon CC, Retinoic acid modulation of transmembrane signaling: Analysis in F9 teratocarcinoma cells. J Biol Chem 265: 17771-17774, 1990.
11. iα2 regulates differentiation of stem cells to primitive endoderm in F9 teratocarcinoma cells. Science 258: 1373-1375, 1992.
12. iα2 enhances phospholipase C signalling. Biochem J 299: 593-596, 1994.
13. iα2 triggers F9 teratocarcinoma stem cell progression via phospholipase C and mitogen-activated protein kinase. J Biol Chem 271: 9002-9008, 1996.
14. i2 induces neoplastic transformation of Rat-1 cells. Proc Natl Acad Sci USA 88: 7031-7035, 1991.
15. Gupta SK, Gallego C, Lowndes JM, Pleimann CM, Sable C, Eisfelder BJ and Johnson GL, Analysis of the fibroblast transformation potential of GTPase-deficient gip2 oncogenes. Mol Cell Biol 12: 190-197, 1992.
16. Lyons J, Landis CA, Harsh G, Vallar L, Grunewald K, Feichtinger H, Suh Q-Y, Clark OH, Kawasaki E, Bourne HR and McCormick F, Two G protein oncogenes in human endocrine tumors. Science 249: 655-659, 1990.
17. α12 gene product. Mol Cell Biol 13: 762-768, 1993.
18. iα to the nucleus. FASEB J 5: 200-206, 1991.
19. i2. J Cell Biol 121: 91-99, 1993.
20. iα2specific antisense RNA in vivo inhibits neonatal growth. Science 260: 991-995, 1993.
21. iα2. Nature 379: 840-844, 1996.
22. iα2deficient mice. Nature Genetics 10: 143-150, 1995.
23. Winitz S, Russell M, Qian N-X, Gardner A, Dwyer L and Johnson GL, Involvement of Ras and Raf in the G-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase. J Biol Chem 268: 19196-19199, 1993.
24. 2-adrenergic receptors expressed in fibroblasts. J Biol Chem 268: 22235-22238, 1993.
25. Wan Y, Kurosaki T and Hunag X-Y, Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors. Nature 380: 541-544, 1996.
26. Milligan G and Wakelam M, (Eds.), G-Proteins. Signal Transduction and Disease. Academic Press, San Diego 1992.
27. Lefkowitz RJ, Turned on to ill effects. Nature 365: 603-604, 1993.
28. Clapham DE, Mutations in G-protein-linked receptors: Novel insights on disease. Cell 75: 1237-1239, 1994.