Protein engineering of the hmg-coa reductase of pseudomonas mevalonii. Construction of mutant enzymes whose activity is regulated by phosphorylation and dephosphorylation

Biochemistry

Volumn 36, Issue 8, 1997, Pages 2173-2177

  Friesen, Jon A ^a,b   Rodwell, Victor W ^a  

^a PURDUE UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE;

ARTICLE; DEPHOSPHORYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME RELEASE; GENETIC ENGINEERING; HYPERCHOLESTEROLEMIA; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PSEUDOMONAS; TARGET CELL;

ANIMALS; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; HYDROXYMETHYLGLUTARYL COA REDUCTASES; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN ENGINEERING; PSEUDOMONAS; SEQUENCE ANALYSIS;

EID: 0031059315     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962254w     Document Type: Article

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