N-(4-hydroxyphenyl)retinamide prevents development of T-lymphomas in AKR/J mice

Anticancer Research

Volumn 17, Issue 1 A, 1997, Pages 499-503

  Chan, Lee Nien Lillian ^a   Zhang, Shuliu ^a   Cloyd, Miles ^a   Chan, Teh Sheng ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

AKR J mice; Chemoprevention; Lymphoma; N (4 hydroxyphenyl)retinamide; Tumor development

Indexed keywords

FENRETINIDE; RETINOIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; APPETITE; ARTICLE; BODY WEIGHT; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; FEMALE; HEALTH; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; T CELL LYMPHOMA;

ANIMALS; ANTICARCINOGENIC AGENTS; BODY WEIGHT; FEMALE; FENRETINIDE; LYMPH NODES; LYMPHOMA, T-CELL; MICE; MICE, INBRED AKR; SPLEEN; THYMUS GLAND;

EID: 0031059195     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Holdener EE and Bollag W: Retinoids. Cur Opin Oncol 5: 1059-1066, 1993.
2. Costa A, De Palo G, Decensi A, Formelli F, Chiesa F, Nava M, Camerini T, Maruhini E and Veronesi U: Retinoids in cancer chemoprevention. Clinical trials with the synthetic analogue fenretinide. Annals NY Acad Sci 768: 148-162, 1995.
3. Lucia MS, Anzano MA, Costa A, Formelli F, Chicsa F, Decensi A, DePalo G and Veronesi U: Prospect of chemoprevention of human cancers with the synthetic retinoid fenretinidc. Cancer Res 54: 2032-2040, 1994.
4. Rotmensz N, DePalo G, Formelli F, Costa A, Maruhini E, Campa T. Crippa A, Danesini GM and Delle-Grottaglie MG: Long-term tolerahility of fenrctinide (4-HPR) in breast cancer patients. Eur J Cancer 27: 1127-1131, 1991.
5. Formelli F, Cleriei M, Campa T, Di Mauro MG, Magni A, Mascotti G, Moglia D, De Palomo G, Costa A and Veronesi U: Five-year administration of fenretinidc: pharmacokineties and effects on plasma retinol concentrations. J Clin Oncol 11: 2036-2046, 1993.
6. Moon RC, Thompson HC, Becci PJ, Gruhbs CJ, Gander RJ, Newton, DL, Smith, JM, Phillips SL, Hendcrson WR, Mullen LT, Brown CC and Sporn MB: N-(4-hydroxphyenyl)retinamide. a new retinoid for prevention of breast cancer in the rat. Cancer Res 39: 1339-1346. 1979.
7. Mariotti A, Marcora E, Bimone G, Costa A, Pierotti MA and Valle GD: N-(hydroxyphenyl)retinamide: a potent inducer of apoptosis in human ncuroblastoma cells. J Natl Cancer Inst 86: 1245-1257, 1994.
8. Delia D, Aiello A, Lombardi L, Pelicci PG, Grignani F Jr, Grignani F, Formelli F, Menard S, Costa A, Veronesi U and Pierotti MA: N-(4-hydroxyphcnyl)retinamidc induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid. CancerRcs 53: 6036-6041, 1993.
9. Oridate N, Lotan D, Xu XC, Hong WK and Lotan R: Differential induction of apoptosis by all-trans-retinoic acid and N-(4-hydroxyphenyl)retinamide in human head and neck squamous cell carcinoma cell lines. Clin Cancer Res 2: 855-858, 1995.
10. Chan L-NL, Zhang SL, Shao JY, Waikel R, Thompson EA and Chan T-s: N-(4-hydroxyphenyl)retinamide induces apoptosis in T lymphoma and T lymphoblastoid leukemia cells. Leukemia and Lymphoma (in press).
11. Hartley JW, Woltord NK, Old LJ and Rowe WP: A new class of murine leukemia virus associated with development of spontaneous lymphomas. Proc Natl Aca Sci (USA) 74: 789-792, 1977.
12. Cloyd MW, Hartley JW and Rowe WP: Lymphomagenicity of recombinant mink cell-focusinducing murine leukemia viruses, J Exp Med 151: 452-552, 1980.
13. Swanson BN, Newton DL, Roller PP and Sporn MB: Biotransformation and biological activity of N-(4-hydroxyphenyl) retinamide derivatives in rodents. J Pharmcol Exp Therapeutics 219: 632-639, 1981.
14. Formelli F, Carsana R, Costa A, Buranelli F, Campa T, Dossena G, Magni A and Pizzichctta M: Plasma retinol level reduction by the synthetic retinoid fenretinide: a one year follow-up study of breast cancer patients. Cancer Res 49: 6149-6152, 1989.
15. Delia D, Aiello A, Formelli F, Fontanclla E, Costa A., Miyashita T, Reed JC and Pierotti MA: Regulation of apoptosis induced by the retinoid N-(4-hydroxyphenyl) retinamide and effect of deregulation bcl-2. Blood 85: 359-367, 1995.
16. Ziv Y, Gupta MK, Milsom JW, Vladisavljevic A, Brand M and Fazio VW: The effect of tamoxiten and fenretininide on human colorectal cancer cell lines m vitro. Anticancer Res 14: 2005-2009, 1994.