Loss of heterozygosity and microsatellite instability in larynx cancer

International Journal of Oncology

Volumn 10, Issue 2, 1997, Pages 247-252

  Louhelainen, Jari ^a   Szyfter, Krzysztof ^b   Szyfter, Witold ^c   Hemminki, Kari ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b POLISH ACADEMY OF SCIENCES   (Poland)

^c POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

larynx cancer; loss of heterozygosity; microsatellite instability; p16; p53

Indexed keywords

MICROSATELLITE DNA;

ADULT; AGED; ARTICLE; CHROMOSOME 17P; CHROMOSOME 9P; CLINICAL ARTICLE; DNA SEQUENCE; FEMALE; HETEROZYGOSITY; HUMAN; LARYNX CANCER; MALE; MUTATION; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE;

EID: 0031058963     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.10.2.247     Document Type: Article

References (59)

1. Parkin DM, Laara E and Muir CS: Estimates of the worldwide frequency of 16 major cancers in 1980's. Int J Cancer 41: 184-197, 1988.
2. Tomatis L (ed): Cancer: Causes, Occurrence and Control. International Agency for Research on Cancer. Scientific Publication, Lyon, 1993.
3. Stell PM and McCormick M: Cancer of the head and neck: are we doing any better? Lancet ii: 1127, 1985.
4. Fraumeni JF: Respiratory carcinogenesis: an epidemiologic appraisal. J Natl Cancer Inst 55: 1039-1046, 1975.
5. Wynder EL, Covey LS, Mabuchi K and Mushinski M: Environmental factors in cancer of the larynx. Cancer 38: 1591-1601, 1976.
6. Baker SR: Malignant neoplasms of the oral cavity. In: Otolaryngology-Head Neck Surgery. Cummings CW, Fredrickson J, Harker LA, Krause CJ and Schuller DE (eds). Mosby-Ycar Book, St. Louis, MO, pp1281-1344, 1986.
7. Brennan JA, Boyle JO, Koch WM, Goodman SN, Hruban RH, Eby YJ, Couch MJ, Forastiere AA and Sidransky D: Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck. N Engl J Med 332: 712-717, 1995.
8. Gusterson BA, Anbazahagan R, Warren W, Midgeley C, Lane DP, O'Hare M, Stamps A, Carter R and Jayatilake H: Expression of p53 in premalignant and malignant squamous epithelium. Oncogene 6: 1785-1789, 1991.
9. Field JK, Spandidos DA, Malliri A, Gosney JR, Yiagnisis M and Stell PM: Elevated p53 expression correlates with a heavy history of smoking in squamous cell carcinomas in head and neck cancer. Br J Cancer 64: 573-577, 1992.
10. Somers KD, Merrick A, Lopex ME, Incognito LS, Schlechter GL and Casey G: Frequent p53 deletions in head and neck cancer. Cancer Res 52: 5997-6000, 1992.
11. Sakai E and Tscuchida N: Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumour suppressor genes. Oncogene 7: 927-933, 1992.
12. Boyle JO, Hakim J, Koch W, van der Riet P, Hruban RH, Roa RA, Correo R, Eby YJ, Ruppert JM and Sidransky D: The incidence of p53 mutations increases with progression of head and neck cancer. Cancer Res 53: 4477-4480, 1993.
13. Bennett WP: P53 alterations in progenitor lesions of the bronchus, esophagus, oral cavity, and colon. Cancer Detection Prev 19: 503-511, 1995.
14. Sarkar FH, Sakr WA, Li Y-W, Jacobs J and Grissman JD: Tumor suppressor p53 gene mutation in squamous cell carcinoma in larynx. Diagn Mol Pathol 5: 201-205, 1996.
15. Mori T, Miura K, Aoki T, Nishira T, Mori S and Nakamura Y: Frequent somatic mutations of the MTS1/CDKN41 (multiple tumor suppressor 1/cyclin-dependent kinase 4 inhibitor) gene in esophaceal squamous cell carcinoma. Cancer Res 54: 3396-3397, 1994.
16. Gonzales MV, Pello MF, Lopezlarrea C, Suarcz C, Medendez MJ and Goto E: Loss of hetcrozygosity and mutation analysis of the pi6 (9p21) and p53 (17p13) genes in squamous cell carcinoma of the head and neck. Clin Cancer Res 1: 1043-1049, 1995.
17. Califano J, van der Riet P, Westra W, Nawroz H, dayman G, Piantadosi S, Corio R, Lee D, Greenberg B, Koch W and Sidransky D: Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res 56: 2488-2492, 1996.
18. Weber JL: Informativeness of human (dC-dA)n*(dG-dT)n polymorphisms. Genomics 7: 524-530, 1990.
19. Weissenbach J, Gyapay G, Dib C, Vignal A, Morisette J, Millasau P, Vaysseix G and Lathrop M: A second-generation linkage map of the human genome. Nature 359: 794-801, 1992.
20. Amos B, Schlötterer C and Tautz D: Social structure of pilot whales revealed by analytical DNA profiling. Science 260: 670-672, 1993.
21. Peinado MA, Malkhosyan S, Velazquez A and Perucho M: Isolation and characterisation of allelic losses and gain in colorectal tumors by arbitrarily primed polymerase chain reaction. Proc Natl Acad Sci USA 89: 10065-10069, 1992.
22. Peltomaki P, Lothe RA, Aaltonen LA, Pylkkanen L, NystromLahti M, Seruca R, David L, Holm R, Ryberg D, Haugen A, Brogger A, Borresen A-L and de la Chapelle A: Microsatellite instability is associated with tumors that characterise the hereditary non-polyposis colorectal carcinoma syndrome. Cancer Res 53: 5853-5855, 1993.
23. Aaltonen LA, Peltomäki P, Leach FS, Sistonen P, Pylkkänen L, Mecklin JP, Järvinen H, Powell SM, Jen J, Hamilton SR, Peterson GM, Kinzler KW, Vogelstein B and de la Chapelle A: Clues to the pathogenesis of familial colorectal cancer. Science 260: 812-816, 1993.
24. Ionov Y, Peinado MA, Malkhosyan S, Shibata D and Perucho M: Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonie carcinogenesis. Nature 363: 558-561, 1993.
25. Thibodeau SN, Bren G and Schaid D: Microsatellite instability in cancer of the proximal colon. Science 260: 816-819, 1993.
26. Lindblom A, Tannegard P, Werelius B and Nordenskjöld M: Genetic mapping of a second locus predisposing to hereditary nonpolyposis colon cancer. Nature Genet 5: 279-282, 1993.
27. Horii A, Han H-J, Shimada M, Yanagisawa A, Kato Y, Ohta H, Yasui W, Tahara E and Nakamura Y: Frequent replication errors at microsatellite loci in tumors of patients with multiple primary cancers. Cancer Res 54: 3373-3375, 1994.
28. Modrich P: DNA mismatch correction. Annu Rev Genet 25: 229-253, 1991.
29. Strand M, Prolla TA, Liskay RM and Petes TD: Destabilisation of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 365: 274-276, 1993.
30. Nawroz H, Koch W, Anker P, Stroun M and Sidransky D: Microsatellite alterations in serum DNA of head and neck cancer patients. Nature Med 2: 1035-1037, 1996.
31. Chen XQ, Stroun M, Magnenat J-L, Nicod LP, Kurt A-M, Lyautey J, Lederrey C and Anker P: Microsatellite alterations in plasma DNA of small cell lung cancer patients. Nature Med 2: 1033-1035, 1996.
32. Adamson R, Jones AS and Field JK: Loss of heterozygosity studies on chromosome 17 in head and neck cancer using microsatellite markers. Oncogene 9: 2077-2082, 1994.
33. Futreal PA, Barrett JC and Wiseman RW: An Alu polymorphism intragenic to the TP53 gene. Nucleic Acids Res 19: 6977, 1991.
34. Jones MH and Nakamura Y: Detection of loss of heterozygosity at the human TP53 locus using a dinucleotide repeat polymorphism. Genes Chromosom Cancer 5: 89-90, 1992.
35. Kwiatkowski DJ and Diaz MO: Dinucleotide repeat polymorphism at the IFNA locus (9p22). Hum Mol Genet 1: 658, 1992.
36. Cannon-Albright LA, Goldgar DE, Neuhausen S, Gruis NA, Anderson DE, Lewis CM, Jost M, Tran TD, Nyguen K, Kamb A, Weaver-Feldhaus J, Meyer LJ, Zone JJ and Skolnick MH: Localization of the 9p melanoma susceptibility locus (MLM) to a 2-cm region between D9S736 and D9S171. Genomics 23: 265-268, 1994.
37. Weber JL: GcneBank database, GDB-ID: G00-180-711, 1991.
38. Ransom DT, Leonard JH, Kearsley JH, Turbett GR, Heel K, Sosars V, Hayward NK and Bishop JF: Loss of heterozygosity studies in squamous cell carcinomas of the head and neck. Head Neck Surgi 8: 248-253, 1996.
39. Field JK, Kiaris H, Risk JM, Tsiriyotis C, Adamson R, Zoumpourlis V, Rowley H, Taylor K, Whittaker J, Howard P, Beirne JC, Gosney JR, Woolgar J, Vaughan ED, Spandidos DA and Jones AS: Allelotype of squamous cell carcinoma of the head and neck: fractional allele loss correlates with survival. Br J Cancer 72: 1188-1190, 1995.
40. Maestro R, Dolcetti R, Gasparotto D, Doglioni C, Pelucchi S, Barzan L, Grandi E and Boiocchi M: High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx. Oncogene 7: 1159-1166, 1992.
41. Scholnick SB, Sun PC, Shaw ME, Haughey BH and El-Mofty SK: Frequent loss of heterozygosity for Rb, TP53 and chromosome arm 3p, but not NME1 in squamous cell carcinomas of the supraglottic larynx. Cancer 73: 2472-2480, 1994.
42. Bockmuhl U, Petersen I and Dietel M: Allelverluste bei plattenepithelkarzinomen des larynx. Laryngo Rhino Otol 75: 48-52,1996.
43. Ahomadegbe JC, Barrois M, Fogel S, Le Bihan ML, Douc-Rasy S, Duvillard P, Armand JP and Riou G: High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumors and métastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal ephitelium and in early non-invasive lesions. Oncogene 10: 1217-1227,1995.
44. El-Naggar AK, Hurr K, Batsakis JG, Luna MA, Goepfert H and Huff V: Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck carcinoma. Cancer Res 55: 2656-2659, 1995.
45. Kiaris H, Spanakis N, Ergazaki M, Sourvinos G and Spandidos DA: Loss of heterozygosity at 9p and 17q in human laryngeal tumours. Cancer Lett 97: 129-134, 1995.
46. Kiaris H and Spandidos DA: Quantitation of the allelic imbalance provides evidence on tumour heterogeneity: a hypothesis. Mutat Res 354: 35-39, 1996.
47. Loeb LA: Microsatellite instability: marker of a mutator phenotype in cancer. Cancer Res 54: 5059-5063, 1994.
48. Strelsingcr G, Okada Y, Emrich J, Newton J, Tsugita A, Tcrzaghi E and Inouye M: Frameshift mutations and the genetic code. Cold Spring Harbor Symp Quant Biol 31: 77-84, 1966.
49. Schlötterer C and Tautz D: Slippage synthesis of microsatellites. Nucleic Acids Res 20: 211-215, 1992.
50. Kornberg A and Baker TA: DNA polymerase I of E. Coli. In: DNA Replication. Freeman WH and Co, NY, pp 147-148, 1992.
51. Tautz D and Schlötterer C: Simple sequences. Curr Opin Genet Dev 4: 832-837, 1994.
52. Dover GA: Evolution of genetic redundancy for advanced players. Curr Opin Genet Dev 3: 902-910, 1993.
53. Richards RI and Sutherland GR: Simple repeat DNA is not replicated simply. Nature Genet 6: 114-116, 1994.
54. Valdes AM, Slatkin M and Freimer NB: AHele frequencies at microsatellite loci: the stepwise mutation model revisited. Genetics 133: 737-749, 1993.
55. Goldstein DB, Linares AR, Cavallisforza LL and Feldman MW: An evaluation of genetic distances for use with microsatellite loci. Genetics 1: 463-471, 1995.
56. Slatkin M: A measure of population subdivision based on microsatellite allele frequencies. Genetics 1: 457-462, 1995.
57. Wooster R, Cleton-Jansen A-M, Collins N, Mangion J, Cornelis RS, Cooper CS, Gusterson BA, Ponder BAJ, von Deimling A, Wiestler OD, Cornelisse CJ, Devilee P and Stratton MR: Instability of short tandem repeats (microsatellites) in human cancers. Nature Genet 6: 152-156, 1994.
58. Field JK, Kiaris H, Howard P, Vaughan ED, Spandidos DA and Jones AS: Microsatellite instability in squamous cell carcinoma of the head and neck. Br J Cancer 71: 1065-1069, 1995.
59. Mao L, Lee DJ, Tockman MS, Erozan YS, Askin F and Sidransky D: Microsatelltte alterations as clonal markers for detection of human cancer. Proc Natl Acad Sci USA 91: 9871-9875, 1994.