Serum fluoride and serum osteocalcin levels in response to a novel sustained-release monofluorophosphate preparation: Comparison with plain monofluorophosphate

Osteoporosis International

Volumn 7, Issue 1, 1997, Pages 48-51

  Battmann, A ^a   Resch, H ^b   Libanati, C R ^c   Ludy, D ^c   Fischer, M ^c   Farley, S ^c   Baylink, D J ^c  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b Medical Department   (Austria)

^c LOMA LINDA UNIVERSITY   (United States)

Author keywords

Bone formation; Monofluorophosphate; Osteocalcin; Osteoporosis

Indexed keywords

FLUORIDE; FLUORIDE SODIUM; FLUOROPHOSPHATE; OSTEOCALCIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; FEMALE; HUMAN; ORAL DRUG ADMINISTRATION; OSSIFICATION; OSTEOPOROSIS; POSTMENOPAUSE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; SUSTAINED RELEASE PREPARATION;

AGED; DELAYED-ACTION PREPARATIONS; DOUBLE-BLIND METHOD; FEMALE; FLUORIDES; HUMANS; MIDDLE AGED; OSTEOCALCIN; OSTEOPOROSIS, POSTMENOPAUSAL; PHOSPHATES;

EID: 0031058433     PISSN: 0937941X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01623460     Document Type: Article

References (16)

1. Farley JR, Wergedal JE, Baylink DJ. Fluoride directly stimulates proliferation and alkaline phosphatase activity of bone-forming cells. Science 1983;222:330-2.
2. Farley SM, Wergedal JE, Farley JR, et al. Spinal fractures during fluoride therapy for osteoporosis: relationship to spinal bone density. Osteoporosis Int 1992;2:213-8.
3. Riggs BL, Hodgson SF, O'Fallen WM, et al. Effect of fluoride treatment on the fracture rate in postmenopausal women with osteoporosis. N Engl J Med 1990;322:802-9.
4. Eriksen EF, Hodgson SF, Riggs BL. Treatment of osteoporosis with sodium fluoride. In: Riggs BL, Melton LJ, editors. Osteoporosis: etiolosy, diangosis and management. New York: Raven Press, 1988:415-32.
5. Malette LE. Letter to the editor. N Engl J Med 1990;323:416.
6. Dambacher MA, Ittner J, Ruegsegger P. Long-term fluoride therapy of postmenopausal osteoporosis. Bone 1986;7:199-205.
7. Delmas PD, Dupuis J, Duboef F, Chapuy MC, Meunier PJ. Treatment of vertebral osteoporosis with disodium monofluorophosphate: comparison with sodium fluoride. J Bone Miner Res 1990; 5(Suppl):143-7.
8. Spak CJ, Sjoestedt P, Eleborg L, Veress B, Perbeck L, Ekstrand J. Tissue response of gastric mucosa after ingestion of fluoride. BMJ 1989;298:1686-7.
9. Ericson Y. Monofluorophosphate physiology: general considerations. Caries Res 1983;17 (Suppl 1): 46-55.
10. Schnitzler CM, Solomon L. Histomorphometric analysis of a calcaneal stress fracture: a possible complication of fluoride therapy for osteoporosis. Bone 1986;7:193-8.
11. Budden FH, Bayley TA, Harrison JE, et al. The effect of fluoride on bone histology in postmenopausal osteoporosis depends on adequate fluoride absorption and retention. J Bone Miner Res 1988;3:127-32.
12. Resch H, Libanati C, Talbot J, et al. Pharmacokinetic profile of a new fluoride preparation: sustained release monofluorophosphate. Calcif Tissue Int 1994;54:7-11.
13. 3 containing tablets for the treatment of osteoporosis. Int J Clin Pharmacol Ther Toxicol 1989;27:242-9.
14. Sakhaee K, Pak CYC. Fluoride bioavailability from immediate-release sodium fluoride with calcium carbonate compared with slow-release sodium fluoride with calcium citrate. Bone Miner 1991;14:131-6.
15. Lian JB, Friedmann PA. The vitamin K dependent synthesis of gamma-carboxyglutamic acid by bone microsomes. J Biol Chem 1978;253:6623-6.
16. Charles B, Hasling C, Risteli L, Risteli J, Misekilde L, Eriksen EF. Assessment of bone formation by chemical markers in metabolic bone disease: separation between osteoblastic activity at the cell and tissue level. Calcif Tissue Int 1992;51:406-11.