Hepatotropic conjugate of adenine arabinoside monophosphate with lactosaminated poly-L-lysine. Synthesis of the carrier and pharmacological properties of the conjugate

Journal of Hepatology

Volumn 26, Issue 2, 1997, Pages 253-259

  Fiume, Luigi ^a   Stefano, Giuseppina Di ^a   Busi, Corrado ^a   Mattioli, Alessandro ^a   Gervasi, Gian Battista ^b   Bertini, Marco ^b   Bartoli, Carlo ^b   Catalani, Robeta ^b   Caccia, Giulio ^b   Farina, Claudio ^b   Fissi, Adriano ^c   Pieroni, Osvaldo ^c   Giuseppetti, Robert ^d   D'Ugo, Emilio ^d   Rapicetta, Maria ^d  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b Laboratori Baldacci   (Italy)

^c CNR Consiglio Nazionale delle Ricerche   (Italy)

^d ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

adenine arabinoside monophosphate; antiviral chemotherapy; asialoglycoprotein receptor; drug targeting; hepatitis B; lactosaminated poly L lysine

Indexed keywords

POLYLYSINE; VIDARABINE PHOSPHATE;

ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CHRONIC HEPATITIS; DRUG CONJUGATION; DRUG ELIMINATION; HEPATITIS B; HEPATITIS B VIRUS; INTRAMUSCULAR DRUG ADMINISTRATION; MOLECULAR WEIGHT; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; RAT; VIRUS HEPATITIS; VIRUS INFECTION;

EID: 0031058406     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(97)80038-4     Document Type: Article

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